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Melatonin 10 mg. - 120 CapsulesPhysioLogics

Item #: 146097
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DROPPED: PhysioLogics - Melatonin 10 mg. - 120 Capsules
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artificial-colors-free IconArtificial Colors Free
yeast-free IconYeast-Free
dairy-free IconDairy-Free
eco-friendly IconEco Friendly
gluten-free IconGluten-Free
lactose-free IconLactose-Free
soy-free IconSoy-Free
sugar-free IconSugar-Free
wheat-free IconWheat-Free
fish-shellfish-free IconFish/Shellfish Free
no-artificial-sweeteners IconNo Artificial Sweeteners
preservatives-free IconPreservatives Free
artificial-flavors-free IconArtificial Flavors Free
starch-free IconStarch Free


120 Capsule
Item #
Ship Weight
0.40 Lb(s)
1 Capsule(s)


    PhysioLogics - Melatonin 10 mg. - 120 Capsules

    PhysioLogics Melatonin 10 mg. is gluten, dairy and wheat free and nutritionally supports relaxation and sound sleep. Melatonin is a natural lipophilic hormone secreted by the pineal gland in the brain, and is classified as an indoleamine. Closely involved in the natural sleep cycle, Melatonin can help support restful sleep patterns. Melatonin may be appropriate for people experiencing occasional sleeplessness, those with jet lag or those wanting to promote sound, quality sleep. These positive findings are most likely mediated through Melatonin’s involvement with membrane-bound receptors located in the suprachismatic nucleus, the pars tuberalis, and other brain regions.

    Melatonin 10 mg. Benefits:

    • Supports relaxation and sound sleep 
    • Those who travel often and experience jet lag can benefit from the convenience of taking only one melatonin tablet to promote tranquil sleep 
    • Participates in free-radical scavenging to support antioxidant action in the brain and across various cellular regions due to its high lipophilicity 
    • Suitable for a wide-range of clients due to its free of status for yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, soy, sodium (less than 5 mg per serving), and artificial color and flavor as certified through analysis of raw material specification sheets.
    • Finished product is suitable for vegetarians 

    Occasional sleeplessness can affect anyone, young or old. The National Institutes of Health recommends to keep a regular schedule of going to bed and waking up at the same time every day, even on weekends, to help your body maintain a normal circadian rhythm. However, due to life's demands this is not realistic for many people. Endogenous melatonin is an important component of your body's circadian rhythm. Supplemental melatonin can provide circadian rhythm support for calm, restful sleep, especially when experiencing occasional sleeplessness or jet lag.

    Structure and Function

    The pineal gland is the organ where information about light and dark is processed and then relayed to cells throughout the body. The eyes deliver information to the pineal gland through different routes that include the retinohypothalamic tract and the suprachiasmatic nuclei. Norepinephrine released from postganglionic nerve endings to the pineal gland helps control melatonin release. This release of norepinephrine to the pinealocytes occurs at night, which is when melatonin secretion and levels throughout the body begin to rise.

    Melatonin, due to its considerable lipophilicity, is able to cross any cell membrane and enter any tissue or cellular compartment. Therefore it is likely that some of melatonin's biochemical effects are elicited through intracellular binding sites in addition to its interactions with membrane-bound receptors (Hardeland, 95). Melatonin's high lipophilicity is what allows it to transmit the signal of darkness to every cell in the body, in turn acting as the eyes for each cell, organ and tissue. This is why melatonin levels throughout the body are so important for promoting calm, restful sleep and a relaxed mood in the evening by supporting natural circadian rhythms.

    In addition to its effects on sleep, Melatonin is believed to play a major role in the biological termination of free-radical induced redox reactions. Melatonin is reported to have a large capacity to trap hydroxyl radicals, the free radical species with the highest relative reactivity. Melatonin also efficiently traps peroxyl radicals and superoxide anions. Melatonin participates in a two-step process in which it first interacts with a hydroxyl or peroxyl radial to give a melatonyl cation radical, which then combines with a superoxide anion to neutralize the electrical charges and pairing electrons.

    High Quality Products

    At PhysioLogics, they monitor and control the purity and quality of every product throughout each stage of the manufacturing process. This dedication to quality is evidenced by their comprehensive in-process quality assurance program — which includes laboratory tests of both raw materials and finished products. They use only the purest ingredients in PhysioLogics vitamins and supplements. In fact, they’re so proud of their ingredients that you’ll find a full label disclosure on every product.

    Product Development and Research Expertise

    Nutritionists, biochemists, food scientists and dieticians staff their top-notch research and development team. They collaborate with experts around the world to bring PhysioLogics customers the latest advancements in nutritional science and technology. From their extensive in-house library, the research team examines the efficacy of nutrients and suggested formulas and thoroughly investigates their safety before suggesting any product for manufacturer. Suggested formulas are sent to their quality control department for prototype development.

    Exceptional Raw Materials

    The superiority of PhysioLogics products begins with the purity and quality of raw materials. All PhysioLogics raw materials are subject to stringent quality control protocols enforced by in-house quality control personnel with the authority to reject, at any time, any material not meeting strict specifications. PhysioLogics routinely tests raw materials for:

    • Authenticity Thin Layer Chromatography
    • Chemical Solvent Residue
    • Dioxins & Dioxin Like Compounds and PCBs (fish oils only)
    • Heavy Metal Screening
    • Herbicide & Pesticide Residue
    • Microbiology Contamination Bacteria Yeast & Mold
    • Peroxides & Anisidines Markers of Rancidity
    • Potency Assay by HPLC, GC, or appropriate test method

    A complete Certificate of Analysis (C of A) accompanies every raw material received into PhysioLogics' warehouse. The Certificate provides vital product information, including the concentration or potency of active constituents. All received raw materials are quarantined and tested before they are allowed to enter the manufacturing core.

    Extensive Laboratory Testing

    Laboratory tests are conducted during each critical stage of manufacture and packaging of PhysioLogics products. Testing these representative samples of both raw materials and finished products throughout the manufacturing process ensures the authenticity, consistency and quality of ingredients. Additional tests used to validate the purity of PhysioLogics products include:

    High Performance Liquid Chromatogrpahy (HPLC)
    This test can analyze the individual ingredients in a mixture. A dissolved, liquid sample is placed in the unit, and the mixture separates into its different components. The amount of each component in the mixture can be measured down to parts per million. Analyzing the HPLC plots can verify the ingredient ratios in a mixture, or identify the purity and potency of a raw material. For example, liquid chromatography can measure the proanthocyanidin content in grape seed or the percentage of ginkgo flavonglycosides in ginkgo biloba.

    Infrared Spectroscopy (FTIR)
    This test validates the authenticity and purity of a sample. A beam of infrared light is passed through a sample. The sample absorbs energy from the beam at certain frequencies. The frequencies are charted, revealing an absorption spectrum. No two herbs or compounds have the exact same absorption spectrum, so by comparing these charts to existing charts, they can positively identify the herb. This test also can tell them exactly the potency of a particular sample of ginkgo compared to another batch that, while looking the same may not be as potent.

    Ultraviolet/Visible Spectrophotometer
    A sample is dissolved in water or alcohol, and a beam of ultraviolet or visible light is passed through the sample solution. The sample absorbs energy from the beam at characteristic frequencies, and the response is recorded, much like the FTIR instrument. While not as specific as FTIR, this technique can identify many herbs which have unique absorbency characteristics.

    Inductively Coupled Plasma Spectrometry (ICP)
    A sample of raw material or finished product is dissolved in acid and sprayed into the middle of a flame burning at an extremely high temperature. Inside the flame, the different elements glow with their own unique colors. A highly sensitive meter graphs the brightness and color of each constituent in the flame and measures, to parts per million, the amount of each constituent present in the sample.

    State of The Art Facility

    Adhering to the highest standards of cleanliness, the manufacturing core is designed to keep outside contaminants from entering the production area. The air within the manufacturing core is pressurized, purified and cleaned by a state-of-the-art climate control system. The manufacturing equipment is disassembled and sanitized routinely between product runs.

    Quality Finished Products

    PhysioLogics, unlike most of their competitors, is committed to full disclosure labels, a hallmark of their dedication to quality and honesty. Healthcare practitioners and patients never will be surprised by unlisted active ingredients in PhysioLogics products.

    PhysioLogics is in full compliance with FDA mandates that nutritional supplement manufacturers meet 100% of label claim (that the amount of an ingredient listed on the label is actually contained in the finished capsule or tablet). All PhysioLogics labels contain lot numbers and expiration dates. Additionally, all labels are tracked and reconciled to ensure that finished products are labeled correctly. All PhysioLogics products must meet finished product assay criteria before they are released into the marketplace.


    For adults, take one (1) capsule at bedtime as Melatonin may produce drowsiness. As a reminder, discuss the supplements and medications you take with your health care providers. Store at room temperature and avoid excessive heat.


    PhysioLogics - Melatonin 10 mg. - 120 Capsules
    Supplement Facts
    Serving Size: 1 Capsule
    Servings Per Container: 120
    Amount Per Serving % Daily Value
    Melatonin 10 mg *
    * Daily Value not established.
    Other Ingredients: Cellulose (Plant Origin), Gelatin, Silica, Vegetable Magnesium Stearate.


    Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Do not drive, operate machinery or consume alcohol when taking this product. Limit use to two months with a break of one week. Not intended for use by persons under the age of 18. Do not use if seal under cap is broken or missing. Keep out of reach of children.



    Making good health accessible is PhysioLogics' top priority. They know that achieving wellness is often difficult, due to conflicting information and rising healthcare costs. As a leading manufacturer of nutritional supplements, PhysioLogics provides healthcare practitioners with high quality nutritional solutions for managing the well being of their patients.

    This dedication to excellence and fair value has engendered the trust of thousands of practitioners and their patients nationwide. For seventeen years, healthcare professionals devoted to delivering accessible health solutions have chosen PhysioLogics.

    Reviews (1)

    5 out of 5 stars
    1 Reviews
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    100% 1 of 1 reviewers would recommend this product to a friend.

    By (Madison, NC)

    This product helps me to fall asleep and stay asleep without having to take strong prescription drugs or the "P.M." products.

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    The products and the claims made about specific products on or through this site have not been evaluated by or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.
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