Balanceuticals Cerebral-Cardiovascular Cleanser Fibrinolytic & Hemolytic, Healthy Blood Circulation to Brain 60 Vegetarian Capsules 500mg. 100% Natural
Made of extracts of astragalus root, Chinese angelica root, common peony root, lumbricus (earthworm), cnidium, safflower flower and peach seed.
Chinese medicine uses this time-honored formula to cleanse arteries and promote healthy blood circulation especially to the brain and heart, and maintain normal functions of the brain and the nervous system.
Modern research found three fibrinolytic and hemolytic enzymes in lumbricus that are important for healthy cerebral-cardiovascular blood flow.
Modern studies on pharmacodynamics reveal that this product yields actions of anti-thrombosis, thrombolysis, dilatation of brain vessels and increasing of its blood flow, improvement of hematology, prevention of acute brain injury, restoration of injured nerve, inhibition of platelet aggregation, cardio tonic, inhibition of plaque formation in atherosclerosis, lowering blood lipid, increasing the tolerance to anoxia and anti-fatigue.
Anti-thrombosis and thrombolysis: Buyang Huanwu decoction 2g/kg administration by stomach perfusion can markedly inhibit the thrombosis formation in rat. Infusion of the solution of Buyang Huanwu decoction into human umbilical vein revealed that the activities of thrombin and fibrinogen are inhibited. To rabbit, Buyang Huanwu decoction 2g/kg is perfused with a result that the thrombolytic action in experimental thrombus in small arteries of rabbit model is strengthened.
Dilatation of brain vessels and increasing of its blood flow: By using rheoencephalograph and resistance graph of the fore limbs of rabbit as index, noradrenalin is injected into rabbit vein in a dose of 0.25-05g/kg, when the graphic amplitude reaches its lowest point, Buyang Huanwu decoction 1.5ml/kg i.v. was given for 5-10 minutes, the amplitude is obviously increased, and the blood flow in the brain is also increased persistently for as long as over one hour. The resistance in brain vessel is decreased.
Improvement of hematology: Rabbit model of cerebral infarction is prepared by compound method. Buyang Huanwu decoction is perfused 7.5g/rabbit/day for 20 consecutive days, the high viscosity of the whole blood and plasma viscosity ratio decreased. The serum cholesterol content also decreased.
Prevention of acute brain injury: Both carotid arteries of rat are fastened to form an acute brain ischemic model. The content of water and Na+ in the brain are used as index. 5 minutes before the re-infusion acute brain ischemia, Buyang Huanwu decoction 14g/kg is injected intraperitoneally, the content of water and Na+ in the brain are greatly decreased, demonstrating that this product can prevent the brain injury caused by re-perfusion in brain ischemia.
Restoration of nerve injury: Guinea pig is injured in its spinal cord to cause hind limbs paralysis, the Buyang Huanwu decoction 4.5g/kg is perfused to the stomach 2 times daily for 7 consecutive days. The injured part received histopathologic exam. The injured neuron of control group is 44.1%, while that of experiment group is 26.4%, demonstrating remarkable restoring action. It is also good for recovery of peripheral nerve injury, with great recovery of nerve conduct speed.
Cardio tonic: Cat’s papillary muscle is used for in vitro experiment. The actual drug concentration is 0.3-0.5g/ml. After medication, the contraction amplitude is increased with a quantity-effect relation, demonstrating a positive action of muscle muscular strengthening. To anesthetized rabbit with open chest, i.v., of Buyang Huanwu decoction 0.5, 1.0, 2.0g/kg is given. It reveals marked and persistent action of increasing the contraction amplitude of myocardium.
Increasing nutrient blood flow in myocardium: Buyang Huanwu decoction is used for gastric perfusion in 4, 8, 16g/kg, the nutrient blood flow increases 1.8%, 132.7%, 192.7% respectively. The last two groups have remarkable increase.
Lowering blood lipid and preventing plaque formation in atherosclerosis: Hyperlipidemia and atherosclerotic models are prepared by feeding high fat diet to rabbit. Buyang Huanwu decoction is given for 30 days by gastric perfusion. The serum cholesterol is much lower than the control group with marked vanishing of plaque. The rapid heart beating during the making of the model is decreased. At the same time, increasing of body weight is also inhibited.
Increasing the tolerance to anoxia and anti-fatigue: Mice are perfused with Buyang Huanwu decoction 2g/kg once daily for 10 days, The time of tolerance to anoxia and swimming time are greatly prolonged.
Anti-inflammation and improvement of immunity: Buyang Huanwu decoction is perfused 10, 20g/kg daily for 10 days. It markedly inhibits the swelling of auricle and inhibits the increased permeability of capillaries induced by di-methyl benzene, increases the weight of immune organs thymus and spleen, increases the specific hemolysin antibody contents and increases phagocytosis of macrophage.