Doctor's Best Green Tea Phytosome Featuring GreenSelect Phytosome - 60 Vegetarian Caplet(s)
Doctor's Best Green Tea Phytosome Featuring GreenSelect Phytosome doubles EGCG's bioavailability due to its molecular bonding with phosphatidylcholine (PC), a vital nutrient that is very well absorbed and co-transports ("chaperones") EGCG into the blood. EGCG (EpiGalloCatechin Gallate) and the other green tea catechin polyphenols have remarkable protective effects on DNA, antioxidant enzymes and other important biomolecules. Their versatile actions help maintain healthy function in the blood vessels, bone, brain, immune system, prostate, skin and other organs, however, oral absorption is limited.
Powerful Support for Circulatory Health
Superior EGCG Bioavailability
Versatile Whole-Body Protection
Benefits of Green Tea Phytosome
Versatile Antioxidant Activity
The four major green tea catechins (EGCG, EGC, ECG, and EC) have different chemical structures, and thus are able to scavenge a variety of free radicals. Some clinical trials suggest that EGCG may have synergistic effects with other catechins, and that metabolic derivatives of EGCG and perhaps the other catechins may have potent bioactivity. Human trials suggest the green tea polyphenols help protect DNA by providing an extra source of dietary antioxidants. Researchers have proposed that the green tea catechins and their metabolic derivatives have antioxidant actions that are both direct (via scavenging radicals) and indirect (by influencing gene activity and up-regulating antioxidant enzymes). Intense physical exercise generates reactive oxygen species (oxygen “free radicals”) that can challenge the body’s antioxidant defenses. In a recent randomized, double-blind, placebo-controlled trial of 35 healthy young men, 17 of them received green tea extract capsules containing 320 mg of polyphenols, while the remaining 18 received a placebo, both for 4 weeks. The men performed a short-term muscular endurance test twice—once before and once after the supplementation period. Supplementation with the extract resulted in a significant increase in total blood polyphenols both at rest and 5 minutes after the endurance test, compared to placebo. This polyphenol increase contributed to enhanced blood antioxidant status at rest, suggesting that the green tea catechins can help offset potential oxidative stress from intense exercise in untrained men. In another recent randomized, double blind, placebo controlled trial, 56 overweight participants received either green tea extract or a placebo with breakfast for 3 months.13 The extract was found to promote healthy metabolic function and a significant increase in total antioxidant status (signifying support against oxidative stress).
Powerful Support for Cardiovascular Health
Clinical research with green tea increasingly demonstrates its potential to enhance cardiovascular and metabolic health. Several epidemiologic studies, most of which examined populations where green tea is commonly consumed, such as in Japan, have reported positive links (“correlations”) between green tea consumption and longstanding cardiovascular health. Maintenance of a healthy vascular endothelium (the single cell layer that lines the blood vessel walls) is critical for the health of the circulatory system, and this is an active of research with green tea. In a few trials that investigated green tea or green tea extracts on vascular function in humans, specific benefits were reported. In one such study 14 healthy women received green tea extract for five weeks. The researchers found significant support for brachial artery function. Specifically, its healthy capacity to dilate in response to increased blood flow was significantly increased. Additionally, the green tea extract significantly improved antioxidant support for the blood.
Green Tea Likey Enhances Brain Function
Epidemiologic (population survey) studies suggest green tea consumption supports brain health. In a study that examined a cross-section of 1,003 elderly Japanese, higher green tea consumption was associated with superior cognitive health. Although clinical evidence is limited, in vitro and animal studies have suggested plausible mechanisms for how green tea catechins may support the aging brain. As examples, the green tea catechins are effective free radical scavengers and also chelate iron, besides having the capacity to positively influence genes that contribute to brain health.
Research is accelerating on the potential health benefits of EGCG for the human brain. In a randomized, double blind, placebo-controlled study, 31 young men and women were given a single dose of either a placebo capsule or capsule containing decaffeinated green tea extract (300 mg, high in EGCG. Compared to placebo, the extract elicited a significant overall increase in alpha, beta, and theta electrical brain wave activity. The researchers noted that it was remarkable to find increased activity across all 3 of these brain bandwidths. Alpha activity is associated with relaxation, beta activity with focused attention, and resting theta activity with quiet wakefulness. This may in part explain reports that drinking green tea can be relaxing while increasing alertness at the same time.
Other Possible Benefits of Green Tea Extract
The green tea catechins continue to be intensively resaerched for a range of other potential health benefits, including metabolic enhancement to facilitate healthy weight management. Responsible research trial design will clarify this potential in the future.
Doctor's Best Questions & Answers
What is modified cellulose and is it safe?
The cellulose is derived from alpha cellulose from softwood pulp. This softwood pulp may be derived from hemlock, spruce or other soft woods. It is made by cooking raw plant fiber in an aqueous solution to separate the cellulose, and then purified. It then goes through extra processing to further break down the fiber. The finished product contains no residual solvents. Excipients are needed to make the materials flow into the capsule and are extremely minute in amounts and are safe.
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or separately. What is the correct usage?
Unless otherwise specified on the label, the product may be taken together or seperately
Is there a limit to how many vitamins can be taken safely in one day?
While our bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician.
What are the other ingredients adn why are they used?
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach.
What is cellulose and modified cellulose produced from?
Souther pine and spruce.
Since Doctor's Best does not manufacture its supplements, how are the purity and integrity of supplements verified? In addition, how are your prices lower than other brands? Does this mean that quality is being compromised?
Doctor's Best supplements are manufactured in the US at cGMP (current Good Manufacturing Practice) certified facilities. All of their manufacturers and suppliers go through their vendor qualification program, which includes inspections and testing, before they agree to work with them. Their finished products have also been tested at the raw material level, in process, and as a finished product to ensure safety and quality. They place the highest importance on safety and quality and do not compromise for the sake of a better price point. The price points are lower because of production size and the overall business structure. They also place great importance on making their supplements available and affordable to those who need them most.
What is HPLC?
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts.
About Doctor's Best
Doctor's Best Quality Standards
Doctor's Best produces products with the highest quality raw materials available on the market. How? They have direct control over and are an integral part of every aspect of product production, from formulation and raw material sourcing to finished product manufacturing. They directly purchase all active ingredients used in their products and use only the highest quality ingredients.
Every product is thoroughly researched and backed by the latest scientific studies conducted in the field. Their formulations reflect the amounts of ingredients shown to be beneficial based on the results of scientific investigations. They use patented, trademarked ingredients backed by scientific studies and clinical research. They never use insignificant quantities to enhance the label.
Doctor's Best directly purchases only the highest grade raw materials from proven and reputable suppliers to be put into product formulations. All raw material suppliers go through their stringent vendor qualification process, which includes a multi-step investigation including all aspects of the production and handling procedures, to insure the highest level of quality is reached.
Doctor's Best formulations are manufactured in HACCP, ISO-9001 and cGMP Certified state-of-the-art facilities to deliver unsurpassed purity and quality. Each Doctor's Best manufacturer goes through rigorous qualification measures to ensure the facility is not only cGMP Certified, but also lives up to the expectations they hold above and beyond FDA regulations for dietary supplements. Beyond ensuring their manufacturers facilities fully comply with GMP regulations, they also ensure each batch of their product is prepared according to GMP procedures. They demand their manufacturers provide documentation to prove compliance.
Whether producing a product with one raw material component or many, each finished product is held to the highest cGMP standards and produced under rigid quality control points to ensure product safety, potency, and uniformity. Their rigorous quality assurance and control processes ensure their customers receive only the highest quality nutritional products that exceed industry standards and provide exceptional nutrition benefits.
Doctor's Best never compromises on ingredients, quality, or science. As a privately owned, independent entity, they answer only to their customers and the retailers who carry their products. They all depend on the integrity of the people and products with whom they deal. Since the day they went into business more than 20 years ago, Doctor's Best has pledged itself to that policy. The bottom line is, if Doctor's Best offers it, it's a proven nutritional concept with genuine health benefits.