Doctor's Best Best EstroG-100 514 mg. - 30 Vegetarian Capsules
Doctor's Best Best EstroG-100 514 mg. features a patented, clinically proven blend of three herbal extracts that together offer relief from the uncomfortable feelings associated with menopause. Research has shown this combination to promote healthy management of hot flashes, night sweats, nervous irritability, dizzy spells, vaginal dryness, numbness and tingling, occasional emotional discontent, and occasional fatigue and sleeplessness. Unlike some common menopause formulations with ingredients that bring safety concerns, EstroG-100 has a track record of safety, and the herbs in it have a long history of use in Asia.
- Relief from hot flashes
- Helps manage mood & energy swings
- Helps alleviate night sweats and promotes restful sleep
- Does not contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives
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Benefits of EstroG-100
About two-thirds of women develop uncomfortable feelings prior to, during, or after menopause. Sleep disruptions, nervous tension, sadness, occasional fatigue, and vasomotor discomforts (hot flashes/cold sweats) are all commonly reported by women. EstroG-100 may help cope with such menopause-related discomforts. EstroG-100 was tested on pre-, peri-, and post- menopausal American women in a randomized, double blind, placebo-controlled trial. The 64 participants took either 514 mg of EstroG-100 or a placebo tablet every day for 12 weeks. To be eligible for the study, women had to have moderate or severe menopausal discomforts as identified by the Kupperman menopausal index (KMI), a questionnaire that measures changes in uncomfortable feelings associated with menopause. Potential benefits were assessed by KMI questionnaires at 6 weeks and at 12 weeks. The KMI evaluates a number of menopausal parameters, including hot flashes/cold sweats, paresthesia (numbness and tingling), sleep interferences, nervousness, melancholia (sadness or gloom), vertigo (dizzy spells), occasional fatigue/weakness, palpitation (pounding of the heart), formication (sensation of crawling of the skin) and muscle or joint discomforts. A separate questionnaire assessed changes in vaginal dryness.
By the end of the study, the average KMI score was significantly lower (indicating improvement) in the EstroG-100 group, compared to the placebo group. Vaginal dryness was also significantly improved in the EstroG-100 group. The individual KMI scores that improved (compared to the control group) were hot flashes/cold sweats, paresthesia, sleep interferences, nervousness, melancholia, vertigo, occasional fatigue/weakness and muscle or joint discomfort. The EstroG-100 group had no major adverse effects. Importantly, this group showed no increase in estrogen or follicle stimulating hormone (FSH) levels. Researchers attributed these impressive benefits to the diverse bioactivity of the non-estrogenic compounds in the three plants that make up EstroG-100. Previous research on EstroG-100 was conducted in Korea, where for centuries these three plants have been traditionally used to promote health. In a randomized, double blind, placebo-controlled trial of 48 perimenopausal women, half were given capsules containing a combination of the herbs in EstroG-100 as the major ingredient (also in the capsules were amino acids, vitamins & minerals, and soy). After 3 months, there was significantly greater improvement in this group over the placebo group. These researchers subsequently reported that in vitro (in an experimental culture system) extracts of all three plants showed estrogen-regulating activity. Furthermore, the mixture of all three showed greater activity than individual extracts, which suggested potential synergistic activity of the three herbs of EstroG-100.
Doctor's Best Quality Promise
Doctor's Best Quality Standards
Doctor's Best produces products with the highest quality raw materials available on the market. How? They have direct control over and are an integral part of every aspect of product production, from formulation and raw material sourcing to finished product manufacturing. They directly purchase all active ingredients used in their products and use only the highest quality ingredients
Every product is thoroughly researched and backed by the latest scientific studies conducted in the field. Their formulations reflect the amounts of ingredients shown to be beneficial based on the results of scientific investigations. They use patented, trademarked ingredients backed by scientific studies and clinical research. They never use insignificant quantities to enhance the label.
Doctor's Best directly purchases only the highest grade raw materials from proven and reputable suppliers to be put into product formulations. All raw material suppliers go through their stringent vendor qualification process, which includes a multi-step investigation including all aspects of the production and handling procedures, to insure the highest level of quality is reached
Doctor's Best formulations are manufactured in HACCP, ISO-9001 and cGMP Certified state-of-the-art facilities to deliver unsurpassed purity and quality. Each Doctor's Best manufacturer goes through rigorous qualification measures to ensure the facility is not only cGMP Certified, but also lives up to the expectations they hold above and beyond FDA regulations for dietary supplements. Beyond ensuring their manufacturers facilities fully comply with GMP regulations, they also ensure each batch of their product is prepared according to GMP procedures. They demand their manufacturers provide documentation to prove compliance.
Whether producing a product with one raw material component or many, each finished product is held to the highest cGMP standards and produced under rigid quality control points to ensure product safety, potency, and uniformity. Their rigorous quality assurance and control processes ensure their customers receive only the highest quality nutritional products that exceed industry standards and provide exceptional nutrition benefits.
Doctor's Best Questions & Answers
What is modified cellulose and is it safe?
The cellulose is derived from alpha cellulose from softwood pulp. This softwood pulp may be derived from hemlock, spruce or other soft woods. It is made by cooking raw plant fiber in an aqueous solution to separate the cellulose, and then purified. It then goes through extra processing to further break down the fiber. The finished product contains no residual solvents. Excipients are needed to make the materials flow into the capsule and are extremely minute in amounts and are safe.
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or separately. What is the correct usage?
Unless otherwise specified on the label, the product may be taken together or separately.
Is there a limit to how many vitamins can be taken safely in one day?
While our bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician.
What are the other ingredients and why are they used?
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach.
What is cellulose and modified cellulose produced from?
Southern pine and spruce.
Since Doctor's Best does not manufacture its supplements, how are the purity and integrity of supplements verified? In addition, how are your prices lower than other brands? Does this mean that quality is being compromised?
Doctor's Best supplements are manufactured in the US at cGMP (current Good Manufacturing Practice) certified facilities. All of our manufacturers and suppliers go through our vendor qualification program, which includes inspections and testing, before we agree to work with them. Our finished products have also been tested at the raw material level, in process, and as a finished product to ensure safety and quality. We place the highest importance on safety and quality and do not compromise for the sake of a better price point. The price points are lower because of production size and the overall business structure. We also place great importance on making our supplements available and affordable to those who need them most.
What is HPLC?
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts.
About Doctor's Best
They firmly believe in the integration of science research and traditional wisdom as the way that nutritional and herbal supplements will reach their exciting potential. Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor's Best offers only the most important nutritional supplements. Careful research and precise formula development keeps them at the leading edge of quality, effectiveness, and innovation. Containing the finest quality raw materials from around the world, Doctor's Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to proliferation of questionable supplements in the marketplace.
Each of their products is accompanied by an annotated "Face Sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations. Traditional wisdom...up-to-date research...product quality you can trust...all the information you need to develop smart strategies for achieving optimal health and well-being. They think you'll agree that this combination of products and services is second to none.