Doctor's Best - Best Bergamonte Polyphenols 250 mg - 60 Vegetarian Capsules
Doctor's Best Bergamonte Polyphenols is a nutrient complex extracted from the exotic bergamot citrus using advanced solvent-free technology. Neoeriocitrin, naringin, and neohesperidin, together with the melitidine and brutelidine unique to this fruit, help account for the exceptional potency and fast-acting effects of this product. In a double-blind clinical trial Doctor's Best Bergamonte Polyphenols provided remarkable support for several key measures of circulatory wellness.
- Promotes healthy blood vessel tone
- Supports healthy cholesterol and triglyceride levels already within the normal range
- Supports healthy blood glucose levels already within the normal range
Building upon remarkable results from animal studies, a groundbreaking bergamot study in humans was published in 2011. In this randomized, double-blind, placebo-controlled trial, 237 participants were given either placebo or bergamot polyphenol fraction (BPF) for 30 days. The study focused on several different cardiovascular parameters, including blood lipids and a subgroup of participants with Metabolic Syndrome (this syndrome is not a disease, but rather a cluster of health factors to keep an eye on). The BPF used in the study was concentrated bergamot juice in powder form, at a dose of either 500 mg or 1000 mg daily, taken before meals. The BPF contained the same five standardized major flavonoids that are in Doctor's Best Bergamonte Polyphenols: neoeriocitrin, naringin neohesperidin, melitidine and brutelidine. The results of this intricate trial were impressive. In just one month, 500 or 1000 mg of bergamot polyphenol was shown to support favorable triglyceride and HDL levels in the majority of participants. Furthermore, BPF was shown to be helpful for the subgroup with Metabolic Syndrome, and measurements of flow-mediated vasodilation suggested support for maintaining healthy vascular tone. The researchers conclude that the results of this study suggest BPF produces complex effects on metabolic regulation, offering a wide range of benefits.
Scientists are still working out which biochemical pathways in the body would explain the beneficial effects of these polyphenols. Since the polyphenols seem to promote several advantageous actions, several theories have been considered. One is that the polyphenols interact with the NF-kB pathway, calming down the transmission of oxidative signals (relieving oxidative stress). Similar to the known activity of flavonoids in other citrus fruits, the positive impact of this is often seen at the level of endothelial cells (those cells lining the blood vessel walls). Another explanation for some ofbergamot’s benefits is that flavonoids such as the melitidine and brutieridine in bergamot juice have structural similarities to an enzyme that influences healthy blood lipid metabolism in the body. Further research in human populations is warranted to confirm the fantastic results that have been reported thus far.
Bergamot is the common name of the fruit Citrus bergamia Risso, a citrus that grows almost exclusively in the southern Calabrian region of Italy, much of it along the coast that lines the Ionian Sea. Customarily valued for its uses in cosmetics and perfumes (through the extraction of its essential oils from the peel), beneficial properties of bergamot towards maintaining cardiovascular wellness—already known in traditional health practices of the region1—are becoming increasingly realized outside of Calabria. The healthful properties of the fruit itself are attributed in large part to its flavonoid content; not only does it contain a tremendous variety of different flavonoids, but a high amount of them. Beyond the more widely studied flavonoids such as the naringin, rutin, neohesperidin, and neoeriocitrin are its lesser-known compounds such as rhoifolin, neodiosmin, melitidin, brutieridin and poncirin. The quantity and quality of these compounds in bergamot make it stand out amongst superfruits.
Doctor's Best Quality Standards
Doctor's Best produces products with the highest quality raw materials available on the market. How? They have direct control over and are an integral part of every aspect of product production, from formulation and raw material sourcing to finished product manufacturing. They directly purchase all active ingredients used in our products and use only the highest quality ingredients.
Science Based Formulations
Every product is thoroughly researched and backed by the latest scientific studies conducted in the field. Their formulations reflect the amounts of ingredients shown to be beneficial based on the results of scientific investigations. They use patented, trademarked ingredients backed by scientific studies and clinical research. We never use insignificant quantities to enhance the label.
Doctor's Best directly purchases only the highest grade raw materials from proven and reputable suppliers to be put into product formulations. All raw material suppliers go through our stringent vendor qualification process, which includes a multi-step investigation including all aspects of the production and handling procedures, to insure the highest level of quality is reached.
Whether producing a product with one raw material component or many, each finished product is held to the highest cGMP standards and produced under rigid quality control points to ensure product safety, potency, and uniformity. Their rigorous quality assurance and control processes ensure our customers receive only the highest quality nutritional products that exceed industry standards and provide exceptional nutrition benefits.
Doctor's Best never compromises on ingredients, quality, or science. As a privately owned, independent entity, their answer only to our customers and the retailers who carry our products. They all depend on the integrity of the people and products with whom they deal. Since the day they went into business more than 17 years ago, Doctor's Best has pledged itself to that policy. The bottom line is, if Doctor's Best offers it, it's a proven nutritional concept with genuine health benefits.
About Doctors Best
Doctor's Best firmly believes in the integration of science research and traditional wisdom as the way that nutritional and herbal supplements will reach their exciting potential.
Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Careful research and precise formula development keeps us at the leading edge of quality, effectiveness, and innovation.
Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to the proliferation of questionable supplements in the marketplace.
Each of their products is accompanied by an annotated "Fact Sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.
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