Biotivia Bio Shape Weight Loss - 60 Capsules
Biotivia Bio Shape inhibits Appetite and Boosts Metabolic Activity. Lose Body Fat, Boost Metabolic Activity, Increase Energy and Activate the SIRT Anti-Aging and Anti-Obesity Genes with Bio Shape. No other non-prescription or prescription weight control product is comparable in terms of potency, safety and efficacy.
Bio Shape combines the six most effective safe natural weight loss extracts into one product with a far higher potency and purity than any other supplement. Bio Shape represents a new and powerful multi-faceted approach to the complex and difficult challenge of weight loss.
There exists no other product which combines the appetite suppresants Organic Green Tea, Fucoxanthin and Garcinia Gambogis with Resveratrol, the SirT-1 anti-aging gene activator.
Why Choose New Bio Shape Resveratrol-Enhanced Weight Loss Supplement?
The Bio Shape Resveratrol weight loss supplement is truly unique. Their new weight loss supplement is the most advanced, most potent, and most effective combination of natural, safe weight loss ingredients ever offered in a single supplement. No other product at any price, with or without a prescription, offers the comprehensive array of anti-obesity agents found in Bio Shape.
If you are looking to lose more than ten or twenty pounds Bio Shape is your best option in a natural, safe, healthy, weight loss supplement.
Tackling the weight loss challenge requires a multi-pronged approach. No one ingredient is the answer. We have combined the most effective weight loss natural compounds into a formulation which brings together the following proven appetite suppresants, fat burners, metabolic boosters, and anti-obesity compounds:
- Resveratrol -- The red wine extract which has been hailed by scientists at Harvard and many other prestigious medical schools and universities as the most important anti-aging, anti-obesity, and pro-health compound in decades. Biotivia is the original manufacturer of the highest bio-available Resveratrol products and is the world's largest Resveratrol manufacturer, which was featured on 60 Minutes on January 25th. This compound is an appetite suppresant, a metabolic enhancer; and in studies at Harvard Medical School was shown to increase the life span of mammals by 31% as well as protect against the ill effects of obesity and aging. Resveratrol activated the Sirtuins which control aging as well as PGC-1 Alpha, a key regulator of energy metabolism. Once PGC-1 alpha is activated, it powerfully induces and coordinates gene expression that stimulates mitochondrial oxidative metabolism in brown fat, fiber-type switching in skeletal muscle, and multiple aspects of the fasted response in liver.
- Organic Green Tea -- Green tea is a rich source of polyphenol catechins. Epigallocatechin gallate (EGCG) is the most active form of the catechins responsible for green tea's antioxidant and metabolic effects. Green tea also contains caffeine, which appears to act synergistically with EGCG to assist metabolism.
- Garcinia cambogia -- Is a thermogenetic (fat buring metabolic effect) agent which has been shown in scientific studies to aid in the reduction and elimination of fat deposits within muscle tissue. This is the internal fat which accumulates in muscles and in and around internal organs that adversly affects health and longevity.
- Gymnema sylvestre 200mg * -- Gymnea sylvestre is has been shown in animal studies to be able to lower the sugar available in the stomach for absorption, raise the insulin levels and block the dietary fat absorption.
- Chromium 160ug* -- A trace mineral essential for the proper utilization of blood sugar. It helps lower triglyceride levels, and lowers body weight while increasing lean body mass.
Why is Bio Shape more effective than previous weight management products?
- Bio Shape reduces appetite and cravings. Controlling appetite is the most critical issue when it comes to weight loss.
- Bio Shape increases your natural fat burning processes by up regulating thermogenesis and fat cell autophagy, the natural destruction of fat cells.
- Bio Shape competes with glucose absorption by mating to receptors in the lining of the intestines thereby reducing absorption of sugars.
- Bio Shape increases energy levels to help with daily calorie consumption and resulting weight loss. Bio Shape supports balanced blood sugar levels.
- Bio Shape helps to reduce the conversion of carbohydrates into body fat.
- Bio Shape provides the full range of health benefits and protection of the red wine molecule Resveratrol, as confirmed by hundreds of clinical and laboratory studies by institutions such as Harvard Medical School.
- Bio Shape Resveratrol not only facilitates weight loss but, more importantly, helps to protect against the serious and potentially debilitating health effects of obesity.
Questions and Answers: Bio Shape Weight Loss Supplement
How does Bio Shape work?
Bio Shape operates through five complimentary pathways:
- Appetite inhibition - This key aid to weight loss is achieved by combining high-potency Resveratrol with Organic Green Tea. Each of these advanced phytonutrients also contribute to the metabolic effect of Bio Shape as well as promote improved general health through their extraordinary antioxidant capacities. In the landmark Harvard study published in the journal Nature Dr. Sinclair discovered that Resveratrol fed to obese mice caused the mice to lose body fat, lowered blood lipids and protected the mice from the normal diseases of aging and obesity. Resveratrol is a sirtuin activator. This means that it switches on the longevity genes in humans.
- Thermogenesis - Increased fat and carbohydrate metabolism is supported by Fucoxanthin and Resveratrol. Fucoxanthin was shown in animal studies to stimulate production of UCP1, a protein that increases the burning of fat. This protein is found in the visceral fat that surrounds internal organs in the abdomen – the type of fat linked to heart disease and metabolic syndrome. Resveratrol increases the density and viability of mitochondria, the energy factories of our cells.
- Increased energy - Garcinia Cambogia fills the glycogen stores in the liver and other tissues, thereby reducing appetite while increasing energy levels. Garcinia Cambogia lowers the production of triglycerides and may also increase thermogenesis, the burning of calories. Resveratrol also increases energy. In a study done by Dr. Auwerx and published in the journal Cell it was shown that Resveratrol increased the physical endurance of mice by 100%. Normal mice can run for one kilometer on a treadmill. Resveratrol fed mice managed two kilometers on average.
- Limits absorption of fats and sugars - The unique shape of Gymnemic acid molecules are similar to that of glucose, allowing it to fill cell receptors in the lining of the intestines, thereby preventing uptake of sugar molecules. Gymnea sylvestre has also been shown in animal studies to be able to lower the sugar available in the stomach for absorption, raise the insulin levels and block the dietary fat absorption.
- Increase antioxidant status - The generation of energy in the body and other processes create free radicals. These super active chemicals destroy cells and have been implicated in a large number of serious diseases. The antioxidants in Bio Shape neutralize these free radicals and provide your body with needed antioxidants while protecting against the damage caused by oxidative stress.
How long will it take to see the effects?
In our trials subjects normally saw positive effects in terms of weight loss and inhibition of appetite as well as increased energy after about 12 days of supplementation with Bio Shape.
How should I take Bio Shape?
You should take one capsule upon waking with a glass of water or low sugar fruit juice. Then you should take one additional capsule approximately one hour prior to eating lunch and one capsule an hour before having dinner for a total of three capsules per day.
Should I take any of the other Biotivia supplements with Bio Shape?
For maximum effect we recommend that you combine your weight loss program with either Bioforte or Transmax, one capsule per day, and Bio Span+. The additional Resveratrol in Transmax or Bioforte amplifies the effects of Bio Shape while the curcumin and silymarin in Bio Span+ operate to protect the body against the inflammatory effects of excess body weight. Body builders who are seeking to reduce body fat while increasing strength and speed recovery from training sessions often find that adding Bio Forge to their regimen is very effective.
How can I maximize weight loss using Bio Shape?
The most effective weight loss program combines Bio Shape with regular exercise, adequate sound sleep, and plenty of water. The best way to control food consumption is to keep a diary in which you enter every food and beverage item consumed and calculate your weekly intake of calories. It is difficult to lose significant amounts of weight unless your daily consumption is less than 2,000 calories.
What is Thermogenesis?
The process by which the body consumes fats and carbohydrates to product heat. Increasing the rate of thermogenesis acts to deplete stores of body fat. Bio Shape supports cell metabolism without stimulating the central nervous system.
What is Fucoxanthin?
A carotenoid similar to those found in tomatoes, red vegetables, and various peppers, fucoxanthin is a powerful free radical scavenger that protects cells from oxidative stress damange. The color of Fucoxanthin comes from the carotenoids it contains. These compounds are powerful antioxidants which participate in the plant's energy production via photosynthesis. Marine plants are extremely healthy sources of vitamins, minerals, protein and other micro-nutrients. Consumption of ocean vegatables such as algae and seaweed has been strongly correlated with lower rates of many serious health conditions. Fucoxanthin is the first marine algae-derived ingredient with a clinically proven thermogenic effect. Bio Shape contains an all-natural food concentrate of fucoxanthin extracted from natural organic marine sources harvested in pristine waters off the coasts of both Europe and Japan.
Bio Shape Resveratrol Weight Loss Supplement Ingredients
Reduce appetite and cravings, Lose body fat, Increase energy, Improve healty and vitality
Trans-Resveratrol 50% 200mg* -- This ingredient alone would make an extraordinary supplement. Bio-enhanced natural Resveratrol modulates the benefits of the other appetite suppressants and metabolic agents contained in this complex and activates the SirT longevity genes. In animal studies Resveratrol prevented onsett of the normal deterioration of aging in obese subjects. The amount of Resveratrol contained in Bio Shape is that which Dr. Mehmet Oz and many other physicians and researchers recommend for optimal life extension. In multiple university studies Resveratrol has been shown to activate PGC-1 Alpha, a key regulator of energy metabolism. Once PGC-1 alpha is activated, it powerfully induces and coordinates gene expression that stimulates mitochondrial oxidative metabolism in brown fat, fiber-type switching in skeletal muscle, and multiple aspects of the fasted response in liver.
Resveratrol has been shown in numerous scientific studies to increase the number, density and efficiency of mitochondria, the fuel burning, energy producing factories in muscle cells. If one looks at a slide containing muscle cells from a person who uses Resveratrol on a regular basis the increased number and health of the mitochondria compared to someone who does not consume Resveratrol are obvious. The muscle of the Resveratrol user will be a deeper red in color and will contain many more mitochondria.
Fucoxanthin 150mg* -- In animal studies, fucoxanthin appeared to stimulate production of UCP1, a protein that increases the burning of fat. This protein is found in the visceral fat that surrounds internal organs in the abdomen – the type of fat linked to serious health conditions.
Organic Green Tea -- Green tea is a rich source of polyphenol catechins. Epigallocatechin gallate (EGCG) is the most active form of the catechins responsible for green tea's antioxidant and metabolic effects. Green tea also contains caffeine, which appears to act synergistically with EGCG to assist metabolism.
Garcinia cambogia 200mg* -- Garcinia Cambogia fills the glycogen stores in the liver and other tissues, thereby reducing appetite while increasing energy levels. Garcinia Cambogia lowers the production of triglycerides and may also increase thermogenesis, the burning of calories. Unlike chemical stimulants commonly used in weight loss products, Garcinia Cambogia does not act on the central nervous system. This means that Garcinia Cambogia will not cause insomnia, nervousness, changes in blood pressure or heart rate and its effectiveness will not diminish with time.
Gymnema sylvestre 200mg* -- Gymnea sylvestre is has been shown in animal studies to be able to lower the sugar available in the stomach for absorption, raise the insulin levels and block the dietary fat absorption.
Chromium 160ug* -- A trace mineral essential for the proper utilization of blood sugar. It helps lower triglyceride levels, and lowers body weight while increasing lean body mass
Why BioShape contains Fucoxanthin
Fucoxanthin is a major marine carotenoid found in edible seaweeds such as Undaria pinnatifida, commonly known as Wakame. Fucoxanthin also has anti-carcinogenec effects, apoptotic effects and free radical scavenging activity. In a study involving obese mice, fucoxanthin was shown to suppress weight gain of white adipose tissue. So strong was this result that the researcher concluded, Because most body fat is stored in white adipose tissue, decreasing white adipose tissue weight by fucoxanthin might be a very effective approach for preventing and/or alleviating obesity.? Maeda H, Hosokawa M, Sashima T, Takahashi N, Kawada T, and Miyashita K: Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. International Journal of Molecular Medicine 18: 147-152, 2006.
The Japanese are well recognized to have the longest life expectancies in the world. Japanese women and men live longer and healthier than everyone else on Earth," says Naomi Moriyama, co-author of Japanese Women Don't Get Old or Fat: Secrets of My Mother's Tokyo Kitchen. One extensive international study, the United Nations World Population Prospects 2006 Revision, listed Japan as first among 194 countries in life expectancy. On the other hand, the United States, even with the best health care in the world, ranked only 34th. Not coincidentally, Japan also has the lowest obesity rate in the urbanized world. Not only can the Japanese expect to live longer but they also live healthier. A native of Japan can anticipate an average of 75 years of healthy living free of disabilities, reports WHO.
In Japan, breakfast is considered to be the most powerful meal of the day. A typical breakfast menu consists of rice, egg or fish, vegetables, fruit, green tea and miso soup. The salubrious effect of Miso soup has received increased attention in recent years. Traditionally added to Miso soup is the extraordinary seaweed known as Wakame.
Wakame Seeweed, the source of Fucoxantin in BioShape
Wakame seaweed (Undaria pinnatifida) is an edible sea vegetable, thought to be one of the first types of marine vegetation appearing on the planet over one billion years ago. It is full of naturally occurring benefits such as Vitamin C, Fiber, Beta-Carotene, pantothenic acid and riboflavin two B Vitamins required for your body to produce energy. It also contains the broadest range of minerals of any food the same minerals found in the ocean and in human blood such as potassium, calcium, magnesium, iron, and iodine. Significantly, Wakame seaweed also has the highest concentrations of naturally occurring Fucoxanthin.
Fucoxanthin is an Important Caratenoid
Commercially, Wakame seaweed is becoming known for its Fucoxanthin, a pigment in the chloroplasts of the brown seaweed responsible for its distinctive color. Fucoxanthin is thought to be a non-stimulant thermogenic, which means it has no effect on the sympathetic nervous system and can be taken without concerns of cardiovascular exhaustion or blood pressure deregulation.
It is also said to initiate the breakdown of fats accumulated by the body’s storing of unburned protein. Fucoxanthin extract has been reported to break apart the stored coupled proteins within the fat cell and effectively turn the stored fat back into protein to be used as energy. Fucoxanthin has been shown to increase the expression of UCP1 in white adipose tissue (WAT). WAT is typically stored by adult humans in the abdomen and is the type of fat responsible for excessive weight gain and obesity. Brown Adipose Tissue (BAT), the good fat?, is important for both basal and inducible energy expenditure in the form of thermogenesis mediated by the expression of the tissue-specific mitochondrial uncoupling protein 1 (UCP1). In humans, UCP1 is usually expressed only in BAT and is a key component for metabolic thermogenesis, a process that prevents an excess of fat accumulation. BAT is considered to affect the whole-body metabolism and may modify sensitivity to insulin and induce the body to resist weight gain. However, adult humans have very little BAT and most fat is stored in WAT. Regulation of UCP1 expression in tissues other than BAT is expected to reduce abdominal fat and certainly is of great interest in the weight control industry. Fucoxanthin has been shown to upregulate the expression of UCP1 in WAT, which may contribute to reducing fatty WAT stores and assist in the battle against obesity.
Studies conducted on Fucoxanthin-fed mice at Hokkaido University indicate that Fucoxanthin has the ability to oxidize fat and release energy by adaptive thermogenesis within WAT fat cells. Research showed a reduction of abdominal WAT weights in laboratory animals by feeding Wakame lipids. This research supports the finding that through the introduction of Fucoxanthin, UCP1 protein can be un-coupled and released from WAT. In the Fucoxanthin-fed animals, WAT weight significantly decreased and UCP1 was expressed in the WAT, while there was no difference in WAT and little expression of UCP1 in the glycolipds-fed mice. The result indicates that Fucoxanthin up regulates the expression of UCP1 in WAT, which may contribute to reducing WAT weight and abdominal fats. So promising was this result that the researchers succinctly concluded that diets containing fucoxanthin might prevent obesity. Accordingly, interest in fucoxanthin has increased, since its activity depends on the protein and gene expresssion. expressions of UCP1 in WAT. Maeda H., Hosokawa M., Shashima T., Takahashi N., Kawada T., Miyashita K. Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells. Intl J Mol Med 18: 147-152, 2006.
In a follow-up study, these same researchers determined that [T]he induction of UCP1 in WAT by food constituent would be important and could become an ideal therapy of obesity.” Maeda H., Tsukui T., Sashima T., Hosokawa M., Miyashita K. Seaweed carotenoid, fucoxanthin, as a multi-functional nutrient. Asia Pac J Clin Nutr 2008; 17 (SI): 196-199. The daily intake of fucoxanthin led to a significant reduction of total body weight. Body weights of laboratory animals fed Wakame lipid was significantly lower than that of controls, even though there were no significant differences in the mean daily dietary intake between the two groups. Essentially, the animals consumed the same amount of calories but those fed fucoxanthin did not accumulate excessive WAT. Further, Fucoxanthin intake also correlated significantly with reduced blood glucose and plasma insulin. Feeding fucoxanthin also significantly increased the level of hepatic docosahexaenoic acid (DHA), a most important n-3 functional polyunsaturated fatty acid in biological systems. The authors concluded, These multi-functionalities of fucoxanthin indicate that it is an important bioactive carotenoid that should be beneficial for the prevention of the metabolic syndrome.? Most pertinently the research confirmed that fucoxanthin is the active component in Wakame lipids that result in the anti-obesity effect. The implication for the weight control industry is clear.
The Fucoxanthin contained in Bio Shape is far more concentrated than that contained in what are called “pure” Fucoxanthin supplements. Wakame itself contains only 0.01% fucoxanthin. The concentrate they use in Bio Shape is 2000 times the of that in Wakame seeweed
Why choose Biotivia?
- With over 20 years of experience processing critical botanicals for the medical and functional food industries, Biotivia designs, formulates and manufactures unique natural herbal supplements which are backed by science and are the most efficacious available in their categories.
- They have a staff of scientists, pharmacists, and physicians at the core of their company.
- They offer high potency, HPLC tested, standardized extracts whose actions and modalities are based on peer-reviewed studies and the knowledge they have gained via collaborations with many of the world’s top universities and medical schools.
- Purity is an obsession with Biotivia and higher purity equals higher potency and fewer side effects. They use the highest quality bio-active extracts and as a result their products are typically higher strength than ordinary supplements and therefore produce effects that you can actually feel.
- They select ingredients for their formulations which have been shown to complement each other's properties.
Each individual product is designed to address specific biological processes and to modulate cellular and genetic pathways known to improve health and wellness.
- Biotivia Resveratrol Product are the overwhelming first choice of the scientific and medical communities doing human clinical trials in the US, Europe, Asia and Australia.
More reasons to choose Biotivia
- They created the world’s original high-potency Resveratrol supplements. They are the Resveratrol specialists and use Trans-Resveratrol (the active form of Resveratrol) in most of their formulations because of its unique and astonishing range of benefits.
- They are the only company to have two Trans-Resveratrol products approved by an internationally recognized and respected independent testing lab. Transmax was the most potent product tested and Bioforte was rated the best value. There is no substitute for truly independent product evaluation.
- Their products are all natural, most are vegan and contain no animal products, preservatives, GMO's or fillers of any kind. No Sirt deactivators such as quercetin are used in any Biotivia supplements. Their capsules are all vegetable Pfizer Vcaps.
- Transmax, their 500mg pure Trans-Resveratrol product, is being used by prestigious universities and hospitals such as Albert Einstein Medical College, UC Davis and Ottawa Hospital for human clinical trials. Their Resveratrol is being used in more human trials than all other brands combined.
- Their products are highly bio-available and effective, as their scientific team understands that real benefits are only achieved when cellular concentrations are reached and maintained. The superior bio-availability of Biotivia Resveratrol has been validated by experts at the National Advertising Division of the US national BBB.
- They manufacturers their own products which are made in accordance with FDA GMP and USP standards in their own facility. They do not buy raw materials from brokers or re-sellers and simply fill capsules.
- Their product is being considered as an IND by the National Institute of Health. No other supplement has met the rigid quality control and purity criteria necessary for this certification.
- They pack their product in nitrogen to maintain its potency and insure at least a 24 month shelf life. They are also the only manufacturer or supplier to utilize a patented active packaging system and oxygen absorbing sachet in the bottle to absorb the free oxygen every time the bottle is opened. This prevents Resveratrol oxidation and preserves potency and bio-activity.
- Many of their customers are Doctors and Healthcare Professionals.
- The bottom line is "Their products work and you will feel the difference in your daily quality of life." Expect more energy, better overall health, clearer mental focus and concentration, better sleep and slower aging.
Biotivia is now part of the AVA family of fine certified products
Biotivia is pleased to announce that the American Vegetarian Association (AVA) has certified Transmax, Bioforte, BioQuench, BioShape, BioSpan, Acai + and Immune Edge+ as Vegan approved supplements.
This is a great achievement as the AVA have tough guidelines and procedures to follow and this is testament that Biotivia go 'above and beyond' to cater for all our customers.
To be awarded this prestigious stamp of approval can give all our vegetarian and Hindu customers extra reassurance that Biotivia is the Number one Vegan supplement company.
About Biotivia Longevity Bioceuticals
Biotivia is fueled by its relentless devotion to vitality, health and wellbeing. Our guiding principle is to develop botanical products that are safe, free of adverse side effects, and uniquely potent and efficacious, that contribute to a significant improvement in a person's quality of life.
In order for Biotivia to make a product there must exist a preponderance of definitive scientific evidence which demonstrates that a natural compound or combination of compounds has important and even necessary health benefits. Our formulas will always be based upon intensive research and collaboration with the scientific and academic communities.
Biotivia Longevity Bioceuticals, LLC is a leading formulator and manufacturer of high potency bioceutical supplements and DNA cosmetic rejuvenation products for the medical, consumer and functional food markets. The company offers products designed to address specific biological processes and to modulate cellular and genetic pathways known to improve health and foster vitality from both the inside out.
James Betz, PhD, Cell Biologist is the Managing Director, and along with his premier team of international longevity research and development scientists have focused on a polyphenolic compound called Resveratrol, demonstrating astonishing DNA repair and anti-aging properties. Biotivia created the first high-potency Resveratrol supplement.
High potency, HPLC tested, standardized extracts are developed into sophisticated supplement formulations with actions and modalities based on peer-reviewed studies. Biotivia products are manufactured in their own facility in accordance with FDA, GMP and USP standards. A patented active packaging system is used for supplement products in order to maintain, bio-activity, potency and insure extended shelf life. Advanced, all-vegetable Pfizer V Licaps are used for encapsulated products in order to prevent oxidation and contamination.
Founded in 1992, Biotivia was originally established in Vienna Austria as a supplier of natural raw materials and botanicals to the supplement and functional food industries and to researchers and scientific institutions worldwide. Biotivia maintains US headquarters in New York and offices in Kansas City, Kansas, Verona, Italy, London and Singapore.
The company has their own in-house scientists, pharmacist, and researchers dedicated to the foremost anti-aging discoveries. Additionally, they collaborate with scientists and universities worldwide on human clinical trials to prove the efficacy of their products. In-house scientists include:
James Betz, Ph.D Cell Biology
Saurabh Shah, Ph.D Biology and Medical Research
Payal Shah, Ph.D Pharmacist
Philip Akers, Chemical Engineering and MBA
Serge Boileau, Ph.Ds Chemistry and Biology and Professor of Biochemistry for 35 years
Abbas Green, MD and PhD, specializing in Endocrinology
Gloria Sabater, Ph.D Pharmacist
Wolf-Dieter Rhewoods Ph. D Professor in Biochemistry