Biotics Research Bio-D-Mulsion - 1 oz.
Biotics Research Bio-D-Mulsion supplies vitamin D3 (400 IU per drop) in an emulsified form to aid in uptake and assimilation, especially important for those with malabsorption issues. Note: Inadequate levels of vitamin D are common. While the importance of vitamin D for musculoskeletal health is well documented, its importance in numerous other aspects of health are now recognized. They include (but are not limited to) cardiovascular health and immune function.
Bio-D-Mulsion & Bio-D-Mulsion Forte from Biotics Research Corporation both supply vitamin D3 as a micro-emulsion for enhanced absorption and utilization, which is particularly important for those with malabsorption conditions. Clinical use of Biotics’ micro-emulsified vitamin D provides significant improvements in serum levels of 25-OH-vitamin D following supplementation.
Bio-D-Mulsion supplies 400 IU of vitamin D3 per drop, while Bio-D-Mulsion Forte supplies 2,000 IU of vitamin D3 per drop.
While we are all familiar with the importance of vitamin D in calcium absorption and bone metabolism, many may not be aware of the recent research on vitamin D and the widening range of applications available for cholecalciferol, which can be classified as both a vitamin and a pro-hormone.1 Additionally, while it has commonly been assumed the upper limit of safe intake is approximately 1,000 IU per day, we now know that the physiologic requirement of vitamin D may be as high as 4,000 IU per day, which is less than half of the 10,000 IU that can be produced endogenously with just a few minutes of sun exposure.
Vitamin D Deficiency and Musculoskeletal Health
Vitamin D deficiency is associated with dull, achy musculoskeletal pain that is incompletely responsive to both pharmacologic and manual therapies. The pain may be widespread or confined to a particular area, most commonly the lower back and lumbar spine. The process by which this occurs has been clearly defined: 1) vitamin D deficiency causes a reduction in calcium absorption, 2) production of parathyroid (PTH) hormone is increased to maintain blood calcium levels, 3) PTH results in increased urinary excretion of phosphorus, which leads to hypophosphatemia,) insufficient calcium phosphate results in deposition of unmineralized collagen matrix on the endosteal (inside) and periosteal (outside) surface of bones,) when the collagen matrix hydrates and swells, it causes pressure on the sensory-innervated periosteum resulting in pain. Indeed, several clinical investigations have recently shown vitamin D deficiency is particularly common among people with musculoskeletal pain.
Non-Musculoskeletal Manifestations of Hypovitaminosis D
Both the peripheral and central nervous systems have multiple sites of action for vitamin D, and it appears likely that vitamin D modulates serotonin and melatonin synthesis and metabolism. Alterations in vitamin D levels appear to explain, at least in part, the adverse psychological effects of sunlight deprivation that often occur due to geographic location and climate. Preliminary evidence suggests vitamin D deficiency may also be particularly common among patients with inflammatory and autoimmune disorders, and that vitamin D may modulate inflammatory responses.
Bio-D-Mulsion and the Importance of Micro-Emulsification
Biotics Research Corporation’s vitamin D is micro-emulsified to enhance absorption and utilization, which are particularly important for those with malabsorption conditions. Independent clinical experience suggests the micro-emulsion form of vitamin D provides significant improvements in serum levels of 25-OH-vitamin D following supplementation.10 Each drop of Bio-D-Mulsion supplies 400 IU of vitamin D3, while each drop of Bio-D-Mulsion Forte supplies 2,000 IU of vitamin D3. With an increased knowledge of the importance of maintaining adequate vitamin D levels, many clinicians recommend supplementation and annual screening for 25-OH-vitamin D levels, especially for patients at risk for deficiency as well as those who may benefit from supplementation.
All Bitoics Research Items are Gluten Free!
Currently, it is believed that gluten sensitivity (gluten intolerance) effects almost 700 million people
worldwide. Gluten intolerance covers a wide spectrum of conditions, including celiac disease and wheat allergy.
Symptoms include bloating, abdominal discomfort, pain, diarrhea, headaches and migraines, lethargy, attention-
deficit disorder, muscular disturbances, bone and joint pain, and even schizophrenia.
At Biotics Research, they provide superior nutritional supplements to benefit the patient health. ALL
BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE and they always have been! With Biotics Research, there's no
need to search through a catalog for all of the ingredients, or review label after label. You can use any product
from Biotics Research without concern because ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE !
Quality Control - What Sets Biotics Apart
The Biotics Research way!
At Biotics Research Corporation, we manufacture our own branded products on site, in our own state
of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site
laboratories, the highly skilled members of our Quality Control Unit, utilize modern, sophisticated technologies
and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in-
process testing, and test all finished products prior to their release for shipment. In fact, many aspects of our
cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary
supplements in order to ensure the safety and effectiveness of our products.
The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures
associated with the production and release of all raw materials, packaging materials and finished products,
including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal
audits, and validates and audits all raw material and packaging suppliers and service vendors as well.
All incoming raw materials are subject to appropriate testing prior to their release for production. Tests
conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold
(including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of
all raw materials and finished products for future testing requirements (raw material stability and finished
product expiration date verification).
All bulk finished products (tablets & capsules) are inspected and subjected to metal detection
prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and
potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior
to packaging as well. Finally, microbiological testing is performed on all finished products and document
reconciliation is completed prior to being released for shipment.
All testing is performed by our trained QC personnel using state of the art laboratory instrumentation including
High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT
-IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC-
Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies
that are being regulated into implementing quality programs, extensive Quality Control has always been part of the
corporate fabric of Biotics Research Corporation.
From day one, the mantra of Biotics Research Corporation has been “Innovation and Quality.” Our goals remain
unchanged – utilize innovative ideas and carefully researched concepts with advanced techniques to develop products
of superior quality and effectiveness – bringing you “The Best of Science and Nature”.