Doctor's Best FibroBoost Featuring Seanol 400 mg. - 270 Veggie Caps
FibroBoost contains Seanol, a unique polyphenol complex from brown algae (Ecklonia cava). Seanol is produced using a patented extraction process that creates a complex of ten sea-based polyphenols. Widely studied for their health benefits, polyphenols are a diverse class of naturally occurring compounds found abundantly in the vegetable kingdom. Polyphenols from land growing plants are largely water soluble, breaking down rapidly in the body when consumed in food. In contrast, Seanol polyphenols are hydrophobic (repelled by water and therefore non-water-soluble); this allows them to remain in the body for up to twelve hours before being metabolized and excreted, greatly enhancing their beneficial health effects.
The polyphenols in Seanol are designated as “phlorotannins” based on their complex chemical structures. Polyphenols are built on a skeleton structure composed of two or more “phenolic rings.” The lauded antioxidant properties of polyphenols stem from the ability of these rings to absorb unpaired electrons from free radicals. Phlorotannins contain numerous phenolic rings, making them powerful free radical scavengers, as confirmed by ORAC analysis. (ORAC is a laboratory analytical technique that measures the in-vitro capacity of a substance to neutralize free radicals.) Patented methods are used to extract and purify polyphenol/ phlorotannins from Ecklonia cava.
- Supports Health and Well-being.
- Benefits Heart Health, Memory Function, Joint Health, Muscle Function, Immune Function, a Normal Inflammatory Response and Healthy Metabolism.
More than thirty million dollars has been invested in the research and development of Seanol. Safety and efficacy have been confirmed in an array of scientific tests that includes in-vitro and in-vivo studies, animal studies and human clinical trials.
Multiple tests and clinical trials reveal physiological effects of Seanol that optimize cardiovascular health. As an antioxidant, Seanol helps maintain healthy blood vessels by protecting the vascular epithelium from free radical attack. Phlorotannins have been shown to boost the antioxidant capacity of serum (serum reducing capacity), as measured by their ability to convert iron in the blood from the ferric form, which is a strong oxidant, to the more benign ferrous iron. Phlorotannins also benefit healthy blood vessels by retarding oxidation of LDL cholesterol and scavenging free radicals that occur in the body such as the DPPH radical and peroxynitrite.
An open-label human clinical trial showed that Seanol supports cardiovascular health by helping to maintain open circulation in arteries, as determined by a 43% increase in flow-mediated dilation (FMD), measured in the brachial artery. (FMD measures the dilation of a blood vessel in response to blood flow through the vessel, providing a gauge of its functional status.) Additionally, Seanol helps maintain healthy endothelial function by regulating the renin-angiotensin-aldosterone system.
Seanol has beneficial effects on mental energy and acuity, as demonstrated in randomized, placebo-controlled studies (unpublished). Results include improvements in cerebral circulation, optimized ratios of alpha to beta brain waves and increases in parasympathetic activity. In another set of studies, students and professional drivers taking Seanol experienced less drowsiness when studying and driving. Seanol raises levels of acetylcholine, one of the body’s major neurotransmitters that control memory and cognition.
Seanol has a favorable influence on the body’s physiological mechanisms that keep joints functioning in a normal state of ease and comfort. In vitro studies reveal down-regulation of prostaglandins involved in this physiology, along with inhibition of biochemical mediators of proteoglycan degradation. These findings point to a protective effect on the structural integrity of joint cartilage.
Seanol has a dampening effect on DGAT, an enzyme that plays a central role in the intestinal absorption of fats, body fat storage and triglyceride levels in the blood. Administered to mice, Seanol reduces deposition of fat in skeletal muscles. These results suggest Seanol may be a valuable addition to weight management programs.
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Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to the proliferation of questionable supplements in the marketplace.