Biotics Research - Equi-Fem for Women - 126 Tablets
Biotics Research Equi-Fem is a comprehensive source of nutrients to support healthy female endocrine function. Includes vitamins, minerals, botanicals and organ/glandular specific support with known nutrient synergist. May be recommended for those having menopausal and peri-menopausal symptoms such as hot flashes, and for general female support.
Premenstrual Syndrome PMS consists of several different symptoms that occur 7 to 10 days before menstruation. The most common symptoms are irritability, bloating, aggressiveness, mastodynia and headaches. PMS is more prevalent among woman working outside the home, alcoholics and women with toxemic tendency. It is probably familial. The cause of PMS is as unclear to us now as it was to Dr. Frank, who first described it in 1931. Some of the possible etiologic factors include progesterone deficiency, prolactin excess, thyroid hypofunction, antidiuretic hormone excess, endorphin activity alterations, serotonin metabolism alterations, prostaglandin action and vitamin deficiency. During the middle age of a woman's life cycle, several health changes and problems may occur. Therefore, middle aged women must manage their health and maintain quality of life by coping with bodily changes. Physiologic changes, directly related to menopausal hormone changes, often impact sexual function, both directly and indirectly. The findings of one study support the relationship between a prior history of PMS and a more problematic menopause transition.
Vitamin B6 is required in the synthesis of neurotransmitters (serotonin from tryptophan and dopamine from tyrosine). It is also needed for the processing of essential fatty acids to prostaglandins.Vitamin B6 has been shown to significantly benefit premenstrual symptoms (feelings of depression, irritability, and tiredness), when given 50 to 100 mg daily. In one study, the nutritional state of 11 women with PMS was evaluated. There was laboratory evidence of significant deficiencies in vitamin B6 and magnesium which improved with vitamin/mineral supplementation.
Vitamin C is essential in the synthesis of the connective tissue proteins, collagen and elastin. In addition, it can regenerate vitamin E as well as quench free radicals.
Vitamin E is the premier lipid soluble anti-oxidant. Vitamin E may help with the normal functioning of the reproductive tract. In a double blind placebo controlled study a significant improvement in certain affective and physical symptoms was noted in subjects supplemented with vitamin E. In another study, 75 women presented with symptoms of PMS, which was scored by a written questionnaire, showed marked improvement after being supplemented with vitamin E for two months (based on the completion of a second questionnaire).
Coenzyme Q10 functions in the mitochondrial electron transport chain for ATP production and is able to regenerate alpha tocopherol from its radical. Folic Acid is a member of the B complex family necessary in the production of red blood cells. Study results indicate that marginal folate deficiency may alter DNA composition and that the suggested RDA may not be sufficient to maintain low homocysteine concentrations of some postmenopausal women.
Vitamin K helps stimulate osteocalcin, which is a bone protein, undergo carboxylation. This process results in carboxyl groups saturating osteocalcin, which can help strengthen bones. Researchers found that women who had daily intakes of at least 109 mcg of vitamin K were 30% less likely to suffer hip fractures than those who consumed less.
Calcium is needed for normal hormone production, neurotransmitter action and smooth muscle responsiveness. In one study healthy, premenopausal women were screened for moderate to severe cyclically recurring premenstrual symptoms. Participants were randomly assigned to receive 1,200 mg of elemental calcium per day or placebo for three menstrual cycles. All symptoms were significantly reduced by the third supplement cycle.
Magnesium is especially required as a catalyst for many intracellular enzymatic reactions, particularly carbohydrate metabolism. Low magnesium concentration is associated with increased irritability of the nervous system, peripheral vasodilation and cardiac arrhythmia. One study showed that within 2 to 4 months of supplementation with magnesium, there was significant improvement in premenstrual mood changes. Another study, in which plasma and erythrocyte magnesium was measured in 105 patients with PMS, showed the erythrocyte magnesium concentration for the patients with PMS was significantly lower than that of a normal population. However, the plasma magnesium did not show this difference indicating an apparent cellular deficiency of magnesium.
Manganese. Premenstrual symptoms (mood and pain) have been shown to respond to manganese supplementation.
FRAC is the trademark of Biotics Research Corporation. FRAC supplies a natural source of plant sterols and soluble ferulic acid. Ferulic acid is believed to be the most active component identified in Gamma Oryzanol. Clinical studies have shown marked improvement of menopausal symptoms when given Gamma Oryzanol.
Black Cohosh (Cimicifuga racemosa) may be an alternative to estrogen replacement for those patients in whom estrogen replacement therapy is either refused or contraindicated. Black Cohosh was widely used by the American Indians and later by American colonists for the relief of menstrual cramps and menopause. It has been suggested that the use of black cohosh may be of benefit in dysmenorrhea and menopausal symptoms.
Dong Quai (Angelica sinensis) has been shown to tone the blood and regulate the menses. It is commonly used for blood deficiency associated with menstrual disorders such as irregular menstruation, amenorrhea, and dysmenorrhea.
As early as the 1920's the effect of Dong Quai on the uterus was a subject of research. In some studies, using direct measurement of the myometrium, administration of dong quai enabled the contractions of the uterus to become more regular. The herb does not appear to have any estrogenic effect.
Neonatal pituitary/hypothalamus. The hypo-thalamus is in charge of many functions, two of which are regulation of body water and regulation of uterine contractibility. Almost all secretion by the pituitary is controlled by either hormonal or nervous signals from the hypothalamus. The anterior pituitary secretes follicle-stimulating hormone(FSH), and luteinizing hormone (LH) that are known to be essential for full function of the ovaries. The ovaries produce two types of sex hormones which are estrogens and progestins. The most important estrogen is the hormone estradiol and the most important progestin is progesterone. The estrogens mainly promote proliferation and growth of specific cells in the body and are responsible for the development of most secondary sexual characteristics of the female. On the other hand, the progestins are concerned almost entirely with the final preparation of the uterus for pregnancy and the breast for lactation.
The adrenal glands are composed of two distinctive parts, the adrenal medulla and the adrenal cortex. The adrenal medulla is functionally related to the sympathetic nervous system; it secretes the hormones, epinephrine and norepinephrine in response to sympathetic stimulation. The adrenal cortex secretes two major types of adrenocortical hormones, the mineralocorticoids and the glucocorticoids. The mineralocorticoids have gained this name because they especially effect the electrolytes of the extra-cellular fluids - sodium and potassium. The glucocorticoids have gained their name because they exhibit an important effect in increasing blood glucose concentration.
All Bitoics Research Items are Gluten Free!
Currently, it is believed that gluten sensitivity (gluten intolerance) effects almost 700 million people worldwide. Gluten intolerance covers a wide spectrum of conditions, including celiac disease and wheat allergy. Symptoms include bloating, abdominal discomfort, pain, diarrhea, headaches and migraines, lethargy, attention- deficit disorder, muscular disturbances, bone and joint pain, and even schizophrenia.
At Biotics Research, they provide superior nutritional supplements to benefit the patient health. ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE and they always have been! With Biotics Research, there's no need to search through a catalog for all of the ingredients, or review label after label. You can use any product from Biotics Research without concern because ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE !
Quality Control - What Sets Biotics Apart
The Biotics Research way!
At Biotics Research Corporation, they manufacture their own branded products on site, in their own state of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site laboratories, the highly skilled members of their Quality Control Unit, utilize modern, sophisticated technologies and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in- process testing, and test all finished products prior to their release for shipment. In fact, many aspects of their cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary supplements in order to ensure the safety and effectiveness of their products.
The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures associated with the production and release of all raw materials, packaging materials and finished products, including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal audits, and validates and audits all raw material and packaging suppliers and service vendors as well.
All incoming raw materials are subject to appropriate testing prior to their release for production. Tests conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold (including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of all raw materials and finished products for future testing requirements (raw material stability and finished product expiration date verification).
All bulk finished products (tablets & capsules) are inspected and subjected to metal detection prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior to packaging as well. Finally, microbiological testing is performed on all finished products and document reconciliation is completed prior to being released for shipment.
All testing is performed by their trained QC personnel using state of the art laboratory instrumentation including High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT -IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC- MS).
Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies that are being regulated into implementing quality programs, extensive Quality Control has always been part of the corporate fabric of Biotics Research Corporation.
From day one, the mantra of Biotics Research Corporation has been "Innovation and Quality." Biotics Research's goals remain unchanged – utilize innovative ideas and carefully researched concepts with advanced techniques to develop products of superior quality and effectiveness – bringing you "The Best of Science and Nature".