Biotics Research Bio-Cyanidins - 60 Tablets
Biotics Research Bio-Cyanidins contains polyphenols from the highest quality pine bar extract (Pycnogenol) and grape seed extract (95% OPCs). Provides superior botanically based antioxidant support.
All higher plants contain an extensive array of polyphenols, flavonoids and complex aromatic compounds. The ability to synthesize these materials probably evolved in order to protect plant tissues from the potentially harmful effects of sunlight and oxygen. Oligomeric proanthocyanidins (abbreviated as OPCs) represent a major class of polyphenols, consisting of dimers, trimers, and tetramers of flavones. Individual members are designated as procyanidin B series or procyanidin C series.
Pycnogenol refers to water-soluble proanthocyanidins extracted from the bark of a European pine, Pinus maritime, by a process patented by Dr. Jacques Masquelier. The extraction process separates Pycnogenol from tannins and polymeric procyanidins. This standardized extract contains 85% proanthocyanidins, together with smaller amounts of ferulic acid, gallic acid and catechin, among others.
Grape Seed Extract (OPCs)
Grape seed OPCs refer to proanthocyanidins extracted from grape seeds (pips) using the same procedure developed for pine bark. Grape pip OPCs contain gallic esters of proanthocyanidins, especially procyanidin B2-3’-0-gallate, and related esters. Historically, isotopically labeled OPCs were isolated from grape vines grown with 14 – CO2 for bioavailability studies. Pycnogenol and grape seed OPCs are similar, though not identical, in composition.
Polyphenols and Antioxidants
Polyphenols, such as proanthocyanidins, are common in the diet and have broad physiologic effects. As an example, many polyphenols and flavonoids have been shown to trap free radicals and prevent oxidative damage in a number of model systems.
Pycnogenol and grape pip OPCs have been studied extensively in Europe and their antioxidant activity has been noted.
Reactive forms of oxygen, such as hydrogen peroxide and superoxide, occur frequently in the body. They are generated by mitochondria and cytochrome P450 detoxication systems; by pollutants such as cigarette smoke, ozone and nitrogen oxides; and by chronic inflammation. Nutrition plays an important role in antioxidant defenses. The body employs protective enzymes, antioxidant nutrients and non-nutrients from food, as well as metabolites, to counter the action of oxidants and free radicals. However, when these defenses are depleted, proteins, lipids in membranes and DNA can be damaged.
All Bitoics Research Items are Gluten Free!
Currently, it is believed that gluten sensitivity (gluten intolerance) effects almost 700 million people
worldwide. Gluten intolerance covers a wide spectrum of conditions, including celiac disease and wheat allergy.
Symptoms include bloating, abdominal discomfort, pain, diarrhea, headaches and migraines, lethargy, attention-
deficit disorder, muscular disturbances, bone and joint pain, and even schizophrenia.
At Biotics Research, they provide superior nutritional supplements to benefit the patient health. ALL
BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE and they always have been! With Biotics Research, there's no
need to search through a catalog for all of the ingredients, or review label after label. You can use any product
from Biotics Research without concern because ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE !
Quality Control - What Sets Biotics Apart
The Biotics Research way!
At Biotics Research Corporation, we manufacture our own branded products on site, in our own state
of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site
laboratories, the highly skilled members of our Quality Control Unit, utilize modern, sophisticated technologies
and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in-
process testing, and test all finished products prior to their release for shipment. In fact, many aspects of our
cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary
supplements in order to ensure the safety and effectiveness of our products.
The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures
associated with the production and release of all raw materials, packaging materials and finished products,
including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal
audits, and validates and audits all raw material and packaging suppliers and service vendors as well.
All incoming raw materials are subject to appropriate testing prior to their release for production. Tests
conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold
(including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of
all raw materials and finished products for future testing requirements (raw material stability and finished
product expiration date verification).
All bulk finished products (tablets & capsules) are inspected and subjected to metal detection
prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and
potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior
to packaging as well. Finally, microbiological testing is performed on all finished products and document
reconciliation is completed prior to being released for shipment.
All testing is performed by our trained QC personnel using state of the art laboratory instrumentation including
High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT
-IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC-
Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies
that are being regulated into implementing quality programs, extensive Quality Control has always been part of the
corporate fabric of Biotics Research Corporation.
From day one, the mantra of Biotics Research Corporation has been “Innovation and Quality.” Our goals remain
unchanged – utilize innovative ideas and carefully researched concepts with advanced techniques to develop products
of superior quality and effectiveness – bringing you “The Best of Science and Nature”.