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Advanced Peptides & Collagen Facial Moisturizer - 2 oz.DERMA-E

Item #: 62012
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DERMA-E - Advanced Peptides & Collagen Facial Moisturizer - 2 oz.
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2 oz.
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0.50 Lb(s)


    DERMA-E - Deep Wrinkle Facial Moisturizer with Peptides- 2 oz. (56 g)

    DERMA-E Deep Wrinkle Facial Moisturizer is a revolutionary double-action peptide cream to visibly soften and smooth the appearance of even the deepest wrinkles. Peptide Matrixyl synthe'6 tells the skin to synthesize new key components such as collagen and to restructure itself. Peptide Argireline helps relax facial muscles, smooth wrinkles, and discourage the formation of new lines. Enriched with anti-aging antioxidants Pycnogenol, Vitamin C and Green Tea, this rich moisturizing formula helps reduce the look of wrinkles, visibly improve skin's resilience, tone and texture, and prevent future damage. Ideal for those with normal to dry skin who are looking for an intense wrinkle-fighting formula that promotes a smoother, more youthful appearance.

    • Promotes a Smoother, More Youthful Appearance
    • Softens & Smoothes the Look of Wrinkles

    DERMA-E's Ingredients
    DERMA-E's passion is all about harnessing nature’s most effective ingredients. They combine potent natural antioxidants, vitamins and botanicals with their doctor formulated expertise to ensure their products deliver unmatched results and provide their consumers with the best skin care possible. Everything they do considers people, the planet and DERMA-E's purpose. That’s why all of their products are:

    • Cruelty Free
    • GMO Free
    • Gluten-Free
    • Soy Free
    • Recyclable

    Clean Formulas
    DERMA-E's 100% vegan, cruelty-free formulas also do not contain parabens, sodium lauryl sulfates, petrolatum, mineral oil or artificial colors.

    Quality Ingredients
    Part of DERMA-E's core ethos is being completely transparent about the ingredients they use. They are proud to state all of the ingredients included in their products on all of their packaging and individual product pages.


    There are so many facial skin care products. How do you choose the right ones for yourself?
    DERMA-E offers a broad range of products to address a wide variety of skin concerns and skin types. To choose the best facial skin care products suited for you, determine what your biggest skin concern is. DERMA-E's products are categorized according to primary skin concerns such as Age Spots, Dark Circles, Sagging Skin and Wrinkles. Additionally, you can select products based upon your skin type, such as Aging/Mature, Dry/Damaged, Combination, Oily/Blemish-Prone or Sensitive.

    Can you use DERMA-E products on an infant or child?
    While DERMA-E stands by the integrity and safety of all their products, they recommend you consult with your doctor or medical practitioner before you start any treatment on an infant or child. Before starting regular use, they recommend conducting a “patch test” for sensitivity on a small area under the ear below the jaw line.

    Do they test on animals or do their products contain animal-derived ingredients?
    No, DERMA-E does not test, and have never tested on animals and their skincare formulas do not contain animal by-products of any kind. As such, the entire DERMA E line of products is vegan and cruelty-free. You will find a cruelty-free symbol on all of their boxes and labels.

    Are there parabens in DERMA E products?
    No, they do not use parabens of any kind to preserve their products. Instead, they have chosen to use alternative preservative systems recognized by the natural health industry.

    Do their products contain fragrances?
    DERMA E offers a wide variety of products, some of which contain naturally-scented essential oils, some of which contain phthalate-free fragrance blends and some of which are completely fragrance-free and scent free.

    Are their products “alcohol-free”?
    Most are, however DERMA-E does utilize plant alcohols (otherwise known as fatty alcohols) in a few products as either an emulsifier (facilitates the mixing of ingredients within a formula) or an emollient (helps to soften and lubricate the skin).

    Are their products safe?
    Yes! DERMA-E formulates every product with ingredients that have been carefully researched and proven safe for topical, external use. Every batch of every product is tested to ensure it is free from microbial contamination. Formulas are also stability tested to ensure they have an effective shelf life.

    Can you use your products if I’m pregnant or nursing?
    While DERMA-E stands by the integrity and safety of all of their products, they recommend you consult with your doctor or medical practitioner before starting any new routine while you are pregnant or nursing.

    Are DERMA-E products “all-natural” and organic?
    DERMA E products are designed to be completely effective, completely vegan and completely delightful. Their formulas are made with a high percentage of natural ingredients carefully selected and sourced from quality, conscientious origins. They will elect to formulate with a synthetic ingredient if the natural alternative proves either to be unstable or animal-derived. Additionally, to maintain product integrity, they formulate with mild stabilizing systems that may be synthetic in nature. DERMA E does use certified organic ingredients when possible.

    What preservatives does DERMA-E use?
    DERMA-E's #1 priority is the safety and efficacy of their products. They use phenoxyethanol and ethylhexylglycerin because they have passed challenge tests where other preservatives have failed. Additionally, they are acceptable according to The European Commission (EU), which has stringent requirements regarding the safety and toxicity of ingredients, and Whole Foods Market, as outlined in their Quality Standards for their Premium Body Care products.

    Additionally, at DERMA-E they are constantly striving to provide the best quality products that deliver results. They are continually researching new ingredients and stabilizing systems to provide you with formulas that are gentle, safe and effective. In order to do this, a preservative system of some form is essential. They use a very small fraction of 1%, in their formulations. Studies have shown that at a 2.2% concentration, these ingredients were nonirritating and nontoxic.

    Do their products expire?
    DERMA-E products do not expire, however they do have a ‘Best If Used By’ date that is three years from the date the product was made. After a product has been opened, the shelf life is 12 months. The number printed on the bottom of each product is the batch code – the date that the product was made. The first two numbers represent the year, the second 2 numbers represent the month, and the final number represents a batch. For example, batch code ‘121031’ indicates the product was the 31st batch made on October, 2012. They have also started putting on a ‘Best if Used By’ date on all of their products. This is written in Month/Year form, i.e., 05/15 represents May 2015.

    Are there ingredients that are not included on the packaging?
    DERMA-E is proud to have full-disclosure labeling, so that all ingredients are listed. For over 30 years, they have taken great pride in the quality of their natural ingredients, and in formulating products that are safe for consumers to use. What you read on the label is actually in the product, and just as importantly, what is in the product is always on the label.

    About DERMA-E

    DERMA E didn’t start out in the beauty aisle or the boardroom. Instead, DERMA-E began in a small health food store in Southern California. Their first product was a jar of Vitamin E 12,000 I.U. Moisturizing Cream. People were amazed at the results it had on their skin and word caught on.

    Over the years DERMA-E introduced many extraordinary products, each one rooted in their belief that skin health can be visibly improved through the right combination of potent vitamins, wholesome nutrients and exceptional ingredients.

    Today DERMA-E has grown to become one of the largest natural facial care brands in the U.S. They attribute their success to honoring their customers with products that promote healthier-looking skin and business ethics that promote a healthier world.

    Nature's Solution's to Healthy Skin
    Since 1984, DERMA-E's passion for health, wellness and environmental sustainability has grown strong. They have high ethical standards and never compromise on skin health and safety. Their 100% vegan, cruelty-free formulas do not contain parabens, sodium lauryl sulfates, petrolatum, mineral oil, artificial colors, gluten, soy or GMOs.

    At DERMA E, they harness nature’s most effective ingredients. Their products are formulated with the most potent natural antioxidants and targeted vitamin solutions to ensure they deliver unmatched results without the use of harmful chemicals.

    Enviromental Commitment
    DERMA E is constantly striving to lessen their impact on the environment and improve their conservation efforts within their organization and they believe they should all do their part to make a positive difference in the sustainability of our world.

    Everything DERMA-E does considers people, the planet and their purpose. Not only do they care about what they put on and in their bodies, but also about what eventually ends up in our waters and ecosystems. That’s why DERMA-E's packaging components are recyclable and they offset 100% of conventional electricity use with wind energy certificates. DERMA-E formulates their Natural Mineral Sunscreens with ingredients identified as safe for coral reef ecosystems. They use nano-particle-free, chemical-free broad spectrum Zinc Oxide, tested and proven to be reef safe.

    Giving Back
    As a company, DERMA-E believes in their collective power to make positive changes in their world, and they are guided by their will to make a meaningful difference. Each and every DERMA E purchase helps to support global communities and the environment. With that said, they proudly support the Paraguay Project, Vitamin Angels, World Wildlife Fund, Heal the Bay and Special Olympics: Ventura County.


    Apply a rich layer onto clean face and neck. Use in the morning and evening. Works well under makeup.


    Purified Water, Glycerin (Vegetable Derived), Caprylic/Capric Triglyceride (Vegetable Derived), Macadamia Ternifolia (Macadamia) Seed Oil, Stearic Acid (Vegetable Derived), Cetyl Alcohol (Plant Derived), Glyceryl Stearate (Vegetable Derived), Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38 (Matrixyl synthe’6), Acetyl Hexapeptide-8 (ArgirelineNP), Panthenol (Provitamin B5), Pinus Pinaster (Pycnogenol) Bark Extract, Tocopheryl Acetate (Vitamin E), Retinyl Palmitate (Vitamin A), Hamamelis Virginiana (Witch Hazel) Extract, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Organic Camellia Sinensis (Green Tea) Leaf Extract*, Organic Chamomilla Recutita (Matricaria) Flower Extract*, Organic Simmondsia Chinensis (Jojoba) Seed Oil*, Allantoin, Dimethicone, Xanthan Gum, Zinc Oxide, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin.


    Avoid contact with eyes. Keep out of reach of children.



    Effective Skin Care: DERMA-E harnesses nature’s most potent vitamins, antioxidants, wholesome nutrients and exceptional ingredients and combines them with doctor-formulated expertise to offer consumers the best eco-ethical skin care possible.

    Healthy Skin, Healthy World: DERMA-E delivers products that are free of GMO’s, gluten and soy, utilize wind energy and are 100% vegan, cruelty-free and recyclable.

    Heritage: California born and raised, DERMA-E is made in the USA and growing strong for over 30 years.

    Reviews (19)

    4.5 out of 5 stars
    19 Reviews
    5 Stars
    4 Stars
    3 Stars
    2 Stars
    1 Stars

    89% 17 of 19 reviewers would recommend this product to a friend.

    By (Wilmington, DE)

    I love this product. A friend said to me a few days ago that I don't have any wrinkles. I do but the are hardly noticeable since I am using Deep Wrinkle Reverse Serum. I will be 70 yrs olds in January.

    Was this review helpful?

    • YES: 5
    • NO: 0
    By (Soledad, CA)

    This is my third purchase of this cream. I am 60, but still have breakouts on my chin. I use this cream every night on my neck, cheeks, forehead, and around my eyes. I use the Skin Biotics from this line on my chin, and it keeps the breakouts at bay. I love the entire line.

    Was this review helpful?

    • YES: 3
    • NO: 2

    Overall, this is a very good moisturizer and it makes my skin look a lot fresher and younger. It has not completely gotten rid of my crows feet and laugh lines though but I can see my neck is firming up with every use. A bit on the pricey side, but I think it is worth it!

    Was this review helpful?

    • YES: 2
    • NO: 0
    By (Port St Lucie, FL)

    I absolutely love this stuff. My skin is firm and I have no wrinkles. I'm 48 and I've had several people say they thought I was 35, loving this!!! This is my new go to cream. I will definitely buy this again.

    Was this review helpful?

    • YES: 2
    • NO: 0
    By (Shokan, NY)

    Wonderful product. At 73 people ask what is my "routine" for such a great complexion. Use derma-e, I tell them.

    Was this review helpful?

    • YES: 2
    • NO: 0

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    The products and the claims made about specific products on or through this site have not been evaluated by or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.
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