Biotics Research EFA-Sirt Supreme - 180 Capsules
Biotics Research EFA-Sirt Supreme supplies a unique, highly concentrated essential fatty acid blend, providing a extremely effective relative combination of EPA, DHA and GLA, with all natural mixed tocopherols, specially formulated to be high in y(gamma)-Tocopherol.
Why do patients need EFA-Sirt Supreme?
The unique composition of EFA-Sirt Supreme provides a balance of key nutrients that current research has shown to support healthy cardiovascular function. A large amount of supportive scientific research shows that the consumption of Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) Omega-3 fatty acids may reduce the risk of coronary heart disease.
Omega-3 fatty acids (FA) have been shown to affect platelet aggregation, blood viscosity, plasma levels of fibrinogen, PF4 and
beta-thromboglobulin and capillary flow. These effects are believed to be functions of membrane fluidity. Omega-3 fatty acids support healthy blood lipid profiles, normal healthy blood pressure, stimulate Nitric Oxide (NO) and support healthy, normal blood sugar and insulin levels. Omega-3 fatty acids help to suppress ACE, TGA beta, SREBP and function as PPAR agonists. Additionally, Omega-3 fatty acid supplementation increases FA oxidation, which research suggests helps to decrease adipose tissue and serves to improve endothelial function.
EPA-derived eicosanoids reduce the production of proinflammatory eicosanoids such as LT-B4, PAF, and cytokines such a TNF-a and IL-1. Evidence suggests that EPA must be incorporated into cell membrane phospholipids for its beneficial affects on eicosanoid metabolism to be realized.
DHA is not only essential for neural function, it is also an important component of cell membranes and supports normal healthy blood pressure. DHA generally appears to improve cell membrane function via improved receptor function and signal transduction. DHA is converted by several mechanisms into docosatrienes and resolvins, which have anti-inflammatory properties. The activity may very well be due to the fatty acids effects modifying genetic expression, according to recent research.
Gamma linolenic acid (GLA), the good Omega-6 fatty acid, is elongated to DGLA, the biologically active form from which eicosanoids are derived. DGLA metabolites reduce the formation of the arachidonate-derived prostaglandins, leukotrienes, platelet-activating factors and supports normal healthy blood pressure. DGLA reduces aldosterone, sympathetic tone and RAAS activity. Low levels of DGLA are associated with increased cardiac risk.
Gamma Tocopherol (g-Tocopherol) Humans derive significant benefit from g-Tocopherol, a key component of the mixed tocopherols supplied by a healthy diet high in vegetable consumption. g-Tocopherol has natriuretic activity, supports normal healthy glucose and insulin levels, and improves antioxidant defenses, serving as a component in minimizing cellular damage resulting from the production of radical oxygen species. Unlike a-Tocopherol, g-Tocopherol and its primary metabolite g-CECH, have been shown to inhibit the synthesis of PGE2.
All Bitoics Research Items are Gluten Free!
Currently, it is believed that gluten sensitivity (gluten intolerance) effects almost 700 million people worldwide. Gluten intolerance covers a wide spectrum of conditions, including celiac disease and wheat allergy. Symptoms include bloating, abdominal discomfort, pain, diarrhea, headaches and migraines, lethargy, attention- deficit disorder, muscular disturbances, bone and joint pain, and even schizophrenia.
At Biotics Research, they provide superior nutritional supplements to benefit the patient health. ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE and they always have been! With Biotics Research, there's no need to search through a catalog for all of the ingredients, or review label after label. You can use any product from Biotics Research without concern because ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE !
Quality Control - What Sets Biotics Apart
The Biotics Research way!
At Biotics Research Corporation, we manufacture our own branded products on site, in our own state of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site laboratories, the highly skilled members of our Quality Control Unit, utilize modern, sophisticated technologies and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in- process testing, and test all finished products prior to their release for shipment. In fact, many aspects of our cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary supplements in order to ensure the safety and effectiveness of our products.
The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures associated with the production and release of all raw materials, packaging materials and finished products, including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal audits, and validates and audits all raw material and packaging suppliers and service vendors as well.
All incoming raw materials are subject to appropriate testing prior to their release for production. Tests conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold (including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of all raw materials and finished products for future testing requirements (raw material stability and finished product expiration date verification).
All bulk finished products (tablets & capsules) are inspected and subjected to metal detection prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior to packaging as well. Finally, microbiological testing is performed on all finished products and document reconciliation is completed prior to being released for shipment.
All testing is performed by our trained QC personnel using state of the art laboratory instrumentation including High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT -IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC- MS).
Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies that are being regulated into implementing quality programs, extensive Quality Control has always been part of the corporate fabric of Biotics Research Corporation.
From day one, the mantra of Biotics Research Corporation has been “Innovation and Quality.” Our goals remain unchanged – utilize innovative ideas and carefully researched concepts with advanced techniques to develop products of superior quality and effectiveness – bringing you “The Best of Science and Nature”.