Life Extension LactoSolv Long-Lasting Lactase - 30 Capsules
Many adults have minimal quantities of lactase in their small intestine, and are unable to digest all but a small amount of lactose. Life Extension LACTOSOLV™ Long-Lasting Lactase contains a novel, food-based “pH neutral lactase” enzyme derived from the yeast Kluyveromyces Lactis, which helps to promote healthy enzymatic activity in the gastrointestinal tract.
Lactase is an enzyme produced on the brush border membrane of the differentiated enterocytes lining the microvilli of the small intestine. Lactase breaks down lactose (a complex sugar that occurs naturally in dairy products) into its two component sugars, galactose and glucose, which are then transported across the lining of the small intestine.
Unlike lactase derived from mold which is only stable in the stomach, the yeast-derived lactase in Life Extension LACTOSOLV™ Long-Lasting Lactase is active in the neutral pH of the small intestine, which is the enzyme's normal site of action. The pH neutral lactase enzyme in Life Extension LACTOSOLV™ Long-Lasting Lactase is enteric-coated and encapsulated in tiny acid-resistant pellets to protect it from the highly acidic, protein-digesting environment of the stomach. The pellets are packaged in small, easy to swallow capsules that dissolve in the stomach within minutes of swallowing. Once released in the stomach, the pellets are transferred within about 15-30 minutes (without digestion) into the small intestine. There, the acid-resistant covering of the pellet is dissolved, releasing the pH neutral enzyme for breakdown of lactose in the small intestine, where lactase is naturally produced by the body.
Each capsule is able to degrade approximately 6.5 grams lactose. (There are approximately 12 grams of lactose in a glass of cow’s milk.) All of the ingredients (active and inactive) are non-GMO.
Frequently Asked Questions
What does Life Extension do to ensure the quality of its products?
They focus on three specific areas.
- Raw Materials: Unlike other supplement companies, the ingredients that go into their supplements are not chosen based on cost. Instead they are chosen based on purity (to ensure contaminants such as microbes and heavy metals comply with regulatory and GMPs requirements), potency, and usage in successful scientific research.
- Validation of the Efficacy of Ingredients by Scientific Research: They use ingredients and dosages that accurately replicate the most successful results obtained in scientific studies for maximum efficacy.
- Manufacturing: Naturally, they are in strict compliance with current Good Manufacturing Practice (GMP) for manufacturing, packaging, and storage.
Are Life Extension products “pharmaceutical grade”?
Life Extension was the first to embrace the concept of pharmaceutical quality materials & manufacturing standards by insisting that the raw materials utilized in their nutritional supplements were of the highest purity available and were consistently tested for any contaminants. However, since the Dietary Supplement Health and Education Act of 1994, regulators defined dietary supplements in a different way than pharmaceutical drugs, making the characterization of a “pharmaceutical grade” dietary supplement problematic. Thus, from a regulatory perspective the term “pharmaceutical” applies to drugs, which dietary supplements are not based on the definitions contained in the 1994 statute. Regrettably, some supplement companies continue to use “pharmaceutical grade” in advertising materials and on product labels in an effort to convey the idea of purity and quality. However, it is not a term regulatory agencies recognize to describe a dietary supplement product, it is misleading and should be avoided.
The Dietary Supplement Health and Education Act of 1994 requires dietary supplements to comply with cGMP which Life Extension rigorously adheres to. Life Extension is GMP registered with NSF International. This registration is based on rigorous bi-annual audits of their distribution operations and quality systems and indicates full compliance with applicable areas of 21 CFR Part 111, Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements. Life Extension is a leader in quality and purity testing and adherence to GMP regulations. They do not use meaningless or inappropriate marketing terms to describe their products.
Does the label accurately list exactly what’s in the bottle?
Yes. All active ingredients from patented, scientifically validated raw materials as well as final, finished products are verified using advanced analytical methods such as HPLC (high performance liquid chromatography), MS (mass spectrometry), etc., to ensure each and every product accurately meets label claims in strict compliance with their demanding product specifications.
What are the “Other Ingredients” on the label, and why are they important?
They are inactive ingredients (excipients) that play a number of critical, essential roles in the manufacturing process including:
- Achieving uniform density for accurate dosing
- Dispersing the active ingredients evenly throughout a solid tablet, capsule, and softgel
- Protecting active ingredients from rapid inactivation due to heat and moisture
- Promoting tablet disintegration, as well as capsule and softgel dissolution
- Sustaining the release of active ingredients into the body over time
Why do some companies refer to these excipients as a threat to your health?
Claiming any product is “pure and free of excipients” can be deceptive advertising, too frequently used to draw attention away from inferior active ingredients! The right inactive ingredients used in the right way do important things … like ensuring that a tablet disintegrates in your GI tract rather than just passing through your system without benefit, or keeping a product from breaking down and being susceptible to microbes. Take Life Extension blueberry extract, for example. It contains AuroraBlue™ wild-harvested, Alaskan blueberries. To retain their nutritional complexity, these berries are freeze-dried and carefully milled for capsule formulation. But being a whole fruit raw material, it tends to want to reconstitute itself with moisture, which would make it a breeding ground for bacteria. So Life Extension uses a drying excipient to keep the milled blueberry material dry, so it can safely deliver its superior nutritional value compared with other, less costly blueberry extracts in most commercial formulations.
All of the excipients Life Extension uses have earned GRAS (“Generally Regarded As Safe”) status … and are used sparingly. In many cases not using them compromises final product quality! Excipients are used in nutritional supplements to ensure uniform density of complex active materials, to achieve even dispersion of active ingredients, and to promote appropriate disintegration and/or dissolution of active ingredients inside your body … to name but a few of the critical roles played by excipients.
Why aren’t Life Extension products organic?
The word “organic” conveys the perception of quality to consumers. But it actually relates to foods that are grown rather than products that are formulated. Many of their scientifically validated raw materials are not produced organically. Rather, their mandate includes rigorous testing and scrupulous processing. The objective is purity … both in terms of their raw materials and their finished products.
About Life Extension
Life Extension was officially incorporated in 1980, but the founders have been involved in anti-aging research since the 1960's. Their long-range goal is to extend the healthy human lifespan. Life Extension supply only the highest quality nutritional supplements, including minerals, vitamins, herbs and hormones.