NOW Foods SAMe 2X 400/200 mg Vegetarian Enteric Coated - 30 Tablets
Now Foods SAMe 2X (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation. Now Foods SAMe 2X can help to temporarily alleviate minor joint discomfort resulting from overexertion or stress. Because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support.
What is SAMe?
- Nervous System Support
- With B-vitamin Cofactors
- Supports Emotional Well-Being
- Supports Joint Health
- Enteric Coated
- Vegetarian Formula
SAMe (S-adenosylmethionine or S-Adenosyl-L-Methionine) is a naturally occurring compound found in all human tissue and organs. It is a building block necessary for the production of many compounds produced by your body, and is used in over 35 different biochemical reactions. SAMe actually donates a part of itself to form these new compounds through a process called methylation, or transmethylation. SAMe is one of the few dietary supplements on the market today that combines the benefits of several nutrients into one, because the body uses the substances produced from SAMe for numerous body processes, including detoxification.Are there any side effects associated with SAMe supplementation?
SAMe is a very safe dietary supplement. Minor side effects include nausea and gastrointestinal irritation, probably due to its sulfur content. But these were only noted at very high doses (1200-1600mg), and the symptoms diminished with continued use. Persons suffering from manic depression (bipolar disorder) should not take SAMe without prior consultation with their physician. If you experience any of these symptoms, it may not be the right supplement for you. The mineral Sulfur is not related to sulfa drugs or allergies related to sulfa drugs.Why is the dosage information with SAMe supplements so confusing?
SAMe in its pure form as found in human cells has a very short life span and is rapidly metabolized into other necessary compounds as needed, which is good! However, this natural form does not allow for the production of a stable, effective dietary supplement. It took scientists years to come up with a way to stabilize SAMe so it could be manufactured as a dietary supplement. It was finally discovered that SAMe (S-Adenosyl-L-Methionine) must be manufactured in a stable salt form (for example, as S-Adenosyl-L-Methionine Disulfate Tosylate) to prevent rapid degradation. In this form, you will actually get 200mg of SAMe compounded in a stable form. However, only half of this 200mg is pure SAMe (S-Adenosyl-L-Methionine). Please note that this salt is not a significant source of sodium.Are there size or color variations with your SAMe products, and should SAMe be refrigerated?
Because of the nature of SAMe, NOW takes special precautions when packaging this product. Extensive stability testing was performed in order to create this uniquely stabilized product. NOW bottles SAMe in amber glass bottles to keep light exposure to a minimum, and keep SAMe products refrigerated in our plant until shipping. It is not necessary to keep SAMe refrigerated after purchase, but it will extend the shelf life of the product. The bottle should be kept closed between uses, away from excessive heat and moisture. Because SAMe is a natural product, there can be variations in color, usually ranging from white to pale yellow or tan. This is normal and does not affe:" ":NOW's Mission
The NOW mission is - To provide value in products and services that empower people to lead healthier lives. NOW Foods is an award-winning and highly respected manufacturer of vitamins, minerals, dietary supplements and natural foods.
In 1948, with the natural food and supplement industry in its infancy, entrepreneur Paul Richard paid $900 for the purchase of Fearn Soya Foods—a Chicago based manufacturer of grain and legume-based products. This began a six-decade legacy of providing health-seeking consumers with high-quality, affordable nutrition products. History of NOW
In 1968, NOW Foods was founded under the belief that good health was not a luxury available only to the wealthy. For the past forty years, NOW has made it their life's work to offer health food and nutritional supplements of the highest quality, at prices that are fair and affordable to all those who seek them. Today, NOW Foods is one of the top-selling brands in health foods stores, an award-winning manufacturer, a respected advocate of the natural product industry, and a leader in the fields of nutritional science and methods development. And while NOW has grown considerably over the past four decades, one thing has never changed – NOW's commitment to providing products and services that empower people to lead healthier lives.NOW Commitments
- Customer Focused and Information Driven - NOW believes that their products, services, and the decisions they make should be primarily influenced by the desires and needs of NOW customers. The decisions that NOW makes should be based on accurate information and therefore NOW places a high value on knowledge and learning within their organization.
- Quality and Value Oriented - Acting in the best interest of NOW customers, NOW endeavors to produce the highest quality products at competitive prices. NOW's first priority is to maintain quality where it counts the most – in the products. NOW's exceptional cost-conscious team of employees then focuses their energies on driving costs down. Nurturing this competency of value drives NOW's ability to provide high quality products at the very best prices.
- Natural is Better - NOW is convinced that natural products are better than their synthetic counterparts and produce better results in human health. Therefore, wherever possible, NOW strives to provide products that contain natural ingredients because they are better for their customers.
NOW's experienced professional and technical staff formulates their products to be of the highest quality. NOW has a group of biochemists, chemists, nutritionists, and food technologists who review current science and nutritional parameters, and formulate our products to be effective for the intended use. NOW's structure/function claims are based on science for active ingredients, and on nutritional science for nutritional content. Serving sizes are based on doses from clinical studies and other published data. NOW's contemporary formulas are designed to meet the health and wellness needs of today’s consumers. NOW uses ingredients that have been tested for effectiveness in clinical trials and laboratory studies. The heart of NOW science is third party independent research. NOW investigates and review clinical studies and other lab studies conducted on their ingredients and their formulas. Best science is used to support best formulations which lead to best quality. NOW products are constantly being tested in clinical trials conducted at top universities and research centers around the country and in various parts of the world. NOW products are being tested to determine:" ": mean health and wellness benefits, which mean quality.GMP Quality Assured
NOW’s GMP certification covers standard operating procedures, employee training, product specifications, expiration dating, vendor certifications and much more. Standard operating procedures include sampling and testing incoming materials according to NOW Foods specifications, inspecting manufacturing processes, and testing finished products to specifications. Tests include organoleptic evaluation (human senses such as sight, taste, smell), physical testing of tablets and capsules, chemical identity of ingredients, potency and contamination testing by the company’s in-house state-of-the-art analytical testing lab, as well as microbiological testing by NOW Foods’ in-house rapid analysis microbiological lab.