Doctor's Best Best PQQ Featuring BioPQQ 20 mg. - 30 Vegetarian Capsules
Doctor's Best Best PQQ Featuring BioPQQ 20 mg. featuring PQQ supplies Pyrroloquinoline Quinone (PQQ), a polyphenol that is an exceptionally potent antioxidant and cell regulator. PQQ is found in common foods and human milk, and is a growth factor for the mitochondria that generate over 90 percent of our life energy. PQQ promotes mitochondrial survival, proliferation, and function. Doctor's Best is pleased to provide the most bioactive PQQ as full clinical potency.
- Science-based nutrition
- Dietary supplement
- Authentic, pure Pyrroloquinoline Quinone
- Ultra-potent antioxidant and other protectant actions
- Promotes mitochondrial survival and energy production
- Does Not Contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives
Benefits of PQQ
At the cell level, PQQ is a biochemical growth factor for mitochondria, the tiny dynamos within our cells that generate over 90 percent of our life energy. PQQ promotes mitochondrial survival, proliferation, and energy-generating performance. Beyond its mitochondrial effects, PQQ also can regulate cell development, cell signaling, even gene functions. In rats and mice, PQQ is known to be a vitamin-like “biofactor” necessary for healthy growth and fitness. For mice, having PQQ in the diet is necessary for healthy circulation, fertility, gastrointestinal function, and immunity. Mice made deficient in PQQ show reduction in both the numbers of mitochondria and the total volume of mitochondria per cell. These mitochondria also function at lower efficiency. PQQ is found in many common human foods, albeit in very small quantities, and is readily absorbed when taken by mouth. It is also present in human breast milk. PQQ has stimulated growth in cultured human cells, even when present at very low levels. In cultured human nerve cells, PQQ stimulated the production of nerve growth factor (NGF), an important growth factor for nerve cells located within and outside the brain.
Two competently performed clinical trials are currently available to document PQQ’s human benefits. The first was conducted in Japan, on office workers with stress-related complaints. (20 mg per day for 8 weeks) improved fatigue recovery, sleep quality, and other quality of life measures. Appetite, vigor, tension, mood, self-control, and confusion were significantly improved. PQQ also significantly improved sleepiness at awakening, sleep onset and maintenance, and sleep duration. An American clinical trial with PQQ was published in summary form, pending full publication. In this trial PQQ showed potent antioxidant and other tissue-supportive effects, and positively influenced mitochondrial function. The full potential of PQQ for human health remains to be elucidated, but it is highly probable that exciting new benefits will be discovered for this biochemically unique nutrient.
Doctor's Best Quality Promise
Doctor's Best Quality Standards
Doctor's Best produces products with the highest quality raw materials available on the market. How? They have direct control over and are an integral part of every aspect of product production, from formulation and raw material sourcing to finished product manufacturing. They directly purchase all active ingredients used in their products and use only the highest quality ingredients
Every product is thoroughly researched and backed by the latest scientific studies conducted in the field. Their formulations reflect the amounts of ingredients shown to be beneficial based on the results of scientific investigations. They use patented, trademarked ingredients backed by scientific studies and clinical research. They never use insignificant quantities to enhance the label.
Doctor's Best directly purchases only the highest grade raw materials from proven and reputable suppliers to be put into product formulations. All raw material suppliers go through their stringent vendor qualification process, which includes a multi-step investigation including all aspects of the production and handling procedures, to insure the highest level of quality is reached
Doctor's Best formulations are manufactured in HACCP, ISO-9001 and cGMP Certified state-of-the-art facilities to deliver unsurpassed purity and quality. Each Doctor's Best manufacturer goes through rigorous qualification measures to ensure the facility is not only cGMP Certified, but also lives up to the expectations they hold above and beyond FDA regulations for dietary supplements. Beyond ensuring their manufacturers facilities fully comply with GMP regulations, they also ensure each batch of their product is prepared according to GMP procedures. They demand their manufacturers provide documentation to prove compliance.
Whether producing a product with one raw material component or many, each finished product is held to the highest cGMP standards and produced under rigid quality control points to ensure product safety, potency, and uniformity. Their rigorous quality assurance and control processes ensure their customers receive only the highest quality nutritional products that exceed industry standards and provide exceptional nutrition benefits.
Doctor's Best Questions & Answers
What is modified cellulose?
The cellulose is derived from alpha cellulose from softwood pulp. This softwood pulp may be derived from hemlock, spruce or other soft woods. It is made by cooking raw plant fiber in an aqueous solution to separate the cellulose, and then purified. It then goes through extra processing to further break down the fiber. The finished product contains no residual solvents. Excipients are needed to make the materials flow into the capsule and are extremely minute in amounts and are safe.
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or seperately. What is the correct usage?
Unless otherwise specified on the label, the product should be taken together or seperately
Is there a limit to how many vitamins can be taken safely in one day?
While their bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician.
What are the other ingredients and why are they used?
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach.
What is cellulose and modified cellulose produced from?
Southern pine and spruce.
Since Doctor's Best does not manufacture its supplements, how are the purity and integrity of supplements verified? In addition, how are your prices lower than other brands? Does this mean that quality is being compromised?
Doctor's Best supplements are manufactured in the US at cGMP (current Good Manufacturing Practice) certified facilities. All of their manufacturers and suppliers go through their vendor qualification program, which includes inspections and testing, before they agree to work with them. Their finished products have also been tested at the raw material level, in process, and as a finished product to ensure safety and quality. They place the highest importance on safety and quality and do not compromise for the sake of a better price point. The price points are lower because of production size and the overall business structure. They also place great importance on making their supplements available and affordable to those who need them most.
What is HPLC?
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts.
About Doctor's Best
They firmly believe in the integration of science research and traditional wisdom as the way that nutritional and herbal supplements will reach their exciting potential. Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor's Best offers only the most important nutritional supplements. Careful research and precise formula development keeps them at the leading edge of quality, effectiveness, and innovation. Containing the finest quality raw materials from around the world, Doctor's Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to proliferation of questionable supplements in the marketplace.
Each of their products is accompanied by an annotated "Face Sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations. Traditional wisdom...up-to-date research...product quality you can trust...all the information you need to develop smart strategies for achieving optimal health and well-being. They think you'll agree that this combination of products and services is second to none.