Doctor's Best - Best Red Yeast Rice with CoQ10 1200 mg - 180 Tablets
Doctors Best Best Red Yeast Rice with CoQ10 contains rice that has been naturally fermented with red yeast (Monascus purpureus) according to traditional methods. Produced domestically, Doctors Best Red Yeast Rice with CoQ10 is similar to red yeast rice that has been used in culinary applications in Asia since at least 800 A.D. Doctors Best Red Yeast Rice with CoQ10 is considered beneficial for adult men and women when taken as part of a lifestyle program that includes regular exercise and a healthy diet.
- Science-based nutrition
- Dietary supplement
- Benefits adult men & women as part of a healthy lifestyle plan
Can I eat grapefruit or drink grapefruit juice while taking Red Yeast Rice?
Grapefruit and grapefruit juice can enhance the effects of Red Yeast Rice and significantly increase blood levels, increasing the risk of side effects and liver damage. Because red yeast rice may act similarly in the body to statins, you should avoid drinking grapefruit juice or eating grapefruit or marmalade while taking red yeast rice.
Can Best Red Yeast Rice be taken before having surgery?
Since the active ingredients in Red Yeast Rice may interact with certain medications, it is best to avoid taking this product for at least a few days before having surgery.
Is there any interaction between Red Yeast Rice & Coumadin?
There is no known interaction between red yeast rice and coumadin, or any other blood thinner.
I read an article that stated that most of today’s Red Yeast Rice supplements contain the mycotoxin citrinin in them as a byproduct of the fermentation process. What assurances are there that citrinin is not in the product that I have purchased?
Doctor's Best tests for citrinin. They test in the parts per billion (ppb's) and it comes up non detectable. This is because they utilize a strain that produces extremely low levels of citrinin.
If I’m sensitive to Black Pepper, can I take BioPerine?
In very rare instances, only someone will be found to be sensitive to BioPerine.
BioPerine is a high purity compound extracted from black pepper and practically devoid other compounds of black pepper, which like safarole, are contributing to the controversy of black pepper being carcinogenic. Piperine is not a carcinogen, and at purity level of minimum 98% (BioPerine) it should not pose any concerns related to black pepper or black pepper extract (see toxicology section in our book on BioPerine).
Those people who are allergic to spices, like peppers, ginger, turmeric, should use piperine containing products with caution. The same is true with any allergen, e.g. milk products should be avoided by those allergic to milk.
The advice of nutritionists to avoid consumption of black pepper in large quantities does not prevent from obtaining benefits from 5 mg of piperine corresponding to 50 mg of black pepper (9%-10% content in raw black pepper). Especially, that our society is on average consuming daily black pepper related products in an average dose of 15-30 mg (calculated from raw black pepper in various foods) of piperine per day!!! The key for patented mechanism of piperine is to be "at the right time at the right place". In other words, to do the job of "nutritionist on call" and disappear.
I have heard that black pepper causes Prostate problems, will BioPerine do the same?
BioPerine is an extract of black pepper. Used in supplements, the quantity ingested is very small. We usually use 1.5 to 5.0 mg per capsule or tablet. Limited studies indicate that Bioperine taken in very large amounts – in the order of magnitude of grams per day (there are 1000 mg in one gram), could lead to intestinal irritation in people sensitive to black pepper. I do not know of any studies suggesting that Bioperine taken in tiny amounts are detrimental to men suffering from prostate conditions.
How long would it take for a TABLET to dissolve?
FDA Rules & Regulations require tablets to dissolve in 45 minutes or less. However, Doctor’s Best has made the requirement to be that tablets must dissolve in 30 minutes or less. Every lot of every tableted product is tested to verify that it dissolves in under 30 minutes.
I am somewhat confused on how to take the DRB products. On many of the labels the Suggested Adult Use will list something along the lines of: Take 2 capsules daily, but it does not state whether they should be taken together or separately. What is the correct usage?
Unless otherwise specified on the label, the product may be taken together or separately.
Is there a limit to how many vitamins can be taken safely in one day?
While our bodies need vitamins and minerals, like other things, if taken in large amounts they may adversely affect health. Large amounts of anything can be toxic. It is important to follow all label directions and discuss any concerns with your physician.
What are the other ingredients and why are they used?
These are used as flow agents and aid in the production to keep the machinery running smoothly and the capsules filling correctly. Similarly for the croscarmellose sodium, which is cellulose (sourced from the cell walls of green plants), and is used to help disintegrate the tablet in the stomach.
What is the croscarmellose sodium excipient that is found in several of the Doctor’s Best products?
Croscarmellose sodium is a commonly used excipient in tablets. It is widely used in the pharmaceutical industry as a "disintegrant," which means it helps tablets break apart in the stomach. In simple terms, croscarmellose sodium is made of cellulose gum with a very small amount of sodium. The sodium content is less than a half a percent (less than 0.5%). (Technically speaking, croscarmellose sodium is defined as "a cross-linked polymer of carboxymethylcellulose sodium.") Croscarmellose sodium is recognized as being essentially non-toxic and non-irritating.
Cellulose is a non-digestible fiber, which means the tiny amount in tablets passes through the gut without being broken down or absorbed. As far as adding to anyone's dietary sodium intake, the amount is too small to be of any consequence (Handbook of Pharmaceutical Excipients, 2nd Ed. American Pharmaceutical Assoc).
What is Silicon Dioxide and how is it produced?
Silicon dioxide is the most abundant mineral in the Earth’s crust, and it is found across the world in various forms. Silicon dioxide (SiO2) in its pure form is colorless to white. Precipitated synthetic amorphous silicas are obtained from a process essentially using sand.
Precipitated silica is a safe (non-crystalline) mineral. According to the relevant United States and European Union standards, precipitated silica is non-hazardous with regard to manufacture, transportation and handling. Precipitated silica is an inert powder and a certified food and feed additive.
Should I be concerned when I see that Silicon Dioxide has been used as an excipient in DRB products?
According to numerous studies reviewed to date on this long-term Generally Recognized As Safe (GRAS) listed food additive, the following was found:
The oral toxicity in mice is greater than (>) 5 grams/kilogram of body weight (Kimmerle 1968), or greater than 350 grams in one dose in humans based on allometric comparisons between mice and humans.
A single dose of 2.5 grams of amorphous polymeric silicon dioxide to human volunteers did not significantly raise the SiO2 excretion in the urine thus suggesting poor absorption of the compound (silicon dioxide)--(Langendorf 1966). Less than one one-hundredth (1000th) of the dose was found in urine, suggesting extremely poor absorption--(Langendorf 1966).
This would suggest that there is no scientific reason to eliminate silicon dioxide as an excipient at the very low levels found in dietary supplements.
Why is silicon dioxide used as an excipient in DRB products?
Silicon Dioxide is commonly used as a flow agent in supplements. It also works as an anti-caking agent, and is added as an ingredient in foods, many multivitamins and mineral supplements because silicon is necessary for good health and is a necessary nutrient for the health of skin, hair, nails and bones.
It seems that information is now out claiming that magnesium stearate is a form of, or implicated in, trans fat, which everyone now regards as being bad. Why does Doctor’s Best use magnesium stearate in its products?
Magnesium Stearate is used to work as a lubricant in the formula. Magnesium Stearate is a salt of stearic acid. Stearic acid is a saturated fatty acid. A trans fatty acid (commonly shortened to trans fat) is an unsaturated fatty acid molecule. Stearic acid, being a saturated fatty acid, is not a trans fat. The magnesium stearate used in Doctor’s Best products is vegetable sourced from palm oil.
What is the source of the cellulose found in the some of the Doctor’s Best products?
The cellulose is made from alpha cellulose from softwood pulp. This softwood pulp may be derived from hemlock, Spruce or other soft woods.
What is the source of the croscarmellose sodium found in the some of the Doctor’s Best products?
It comes from pulp (cotton). It is non-GMO (genetically modified organism).
What is HPLC?
HPLC stands for "High Performance Liquid Chromatography." This is an analytical lab testing method that is used to quantify the active ingredients. It is considered to be a very sensitive and accurate test. HPLC testing is a tool recognized as a quality benchmark for herbal extracts.
Does cellulose interfere with the absorption of supplements?
Dietary fiber in general is known to change intestinal viscosity, nutrient absorption, transit time, and gut hormones. Although there is some evidence from animal studies that large amounts of cellulose in the diet (6-12% of diet) can interfere with nutrient absorption (particularly minerals), there is no evidence that the small amount in capsules interfere with nutrient absorption, as there are many pharmacokinetic studies that have been conducted with nutrients in cellulose capsules, demonstrating the ability of the nutrients to be effectively absorbed.
What is the maximum dosage for BioPerine?
Black pepper has been consumed safely for thousands of years and has been deemed GRAS (generally recognized as safe) by the FDA for the intended use as a spice. However, there are limited toxicology studies on black pepper and/or black pepper extract and limited human clinical studies as well. Therefore, it is difficult to determine an "upper limit" and none has been suggested.
Why is there a soy warning on Best Red Yeast Rice?
Soy flour is used in manufacturing to process the material.