Thorne Research Animal Health CurcuVET-EQ - 5.8 oz. (165 g)
Thorne Research Animal Health CurcuVET-EQ is a unique, patented curcumin product available exclusively from Thorne Vet. For centuries people throughout Asia have benefited from the healthful effects of curcumin. Curcumin is the orange pigment in turmeric (the primary ingredient in curry) and is a potent antioxidant that offers numerous health benefits including for joint health, hepatic support, gastrointestinal health, and cardiovascular function – by helping to maintain the animal's normal inflammatory response.
Thorne Research Animal Health CurcuVET-EQ
Curcumin complexed with phosphatidylcholine for superior bioavailability:
- for maintenance of the animal's normal inflammatory response
- provides potent antioxidant and hepatoprotective activity
- significantly increased bioavailability from the phytosome preparation
Thorne Research Animal Health CurcuVET-EQ is a unique curcumin extract that is significantly better absorbed than other curcumin extracts. Whether taken as a supplement or from food, curcumin is generally poorly absorbed into the bloodstream. Scientists at Indena S.p.A., the worldwide experts in botanical extract technology, have uncovered the key to curcumin absorption – phytosome technology. Phytosomes are plant extracts bound to a phospholipid, in this case phosphatidylcholine (PC), an essential component of cell membranes. When taken orally, PC is very well absorbed. By attaching a curcumin molecule to a PC molecule, the PC ushers the curcumin across the cell membrane for superior absorption.
Studies demonstrate Thorne Research Animal Health CurcuVET-EQ supports a healthy inflammatory response in small animals and horses. A recent European study analyzed the bioactivity of Thorne Research Animal Health CurcuVET-EQ compared to non-steroidal anti-inflammatory drugs and found their bioactivity was similar. The study's sponsors, who were studying canine arthritis, found CurcuVET was effective in down-regulating the pro-inflammatory substances, tumor necrosis factor-alpha (TNF-a) and nuclear factor-kappaB (NF-?B). A similar equine study on the effect of Thorne Research Animal Health CurcuVET-EQ on cytokine gene expression found significant down-regulation of interleukin (IL)-1ß and IL-1RN in mares and inhibition of cyclooxygenase-2, TNF-a, and IL-1RN and increase in IL-6 in foals. Similar results were achieved in an eight-month human trial of Meriva. Enhanced joint health was reflected in improvements in both clinical and biochemical end points.
A 2007 study published in the journal, Cancer Chemotherapy and Pharmacology, demonstrated the superior bioavailability of curcumin phytosome (as Meriva, the Thorne Research Animal Health CurcuVET-EQ equivalent for humans) compared to ordinary curcumin. Liver levels of curcumin were also higher with this supplementation. In a more recent, randomized, single-blind, crossover study in nine humans, total curcuminoid bioavailability as evaluated by the plasma area under the curve (AUC) was about 29-fold higher for Meriva than for the conventional turmeric extract.
Curcumin has demonstrated its potential to help maintain the animal's normal inflammatory response. In numerous animal studies, curcumin has shown the ability to help maintain healthy intestinal mucosa under various adverse conditions. Among the effects noted in the various trials have been decreased nuclear factor-kappaB, nitric oxide, and free radicals in the colonic mucosa. For example, a small human pilot study on patients who had poor gastrointestinal health demonstrated that the administration of curcumin improved overall well-being, maintained the levels of biomarkers generally associated with the body's normal inflammatory response, and served as a non-drug adjunct that did not disrupt the use of conventional medications.
Several studies have illustrated curcumin's hepatoprotective effects, leading researchers to suggest its use can protect the liver from exogenous insults from environmental toxins. Curcumin also has the capacity to increase both the flow and solubility of bile. Curcumin's hepatoprotective effects are due in part to direct free radical scavenging; but curcumin also enhances the animal's natural antioxidant system, which increases glutathione levels, thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.
A recent European canine study found Thorne Research Animal Health CurcuVET-EQ was effective in helping to maintain the balance of markers associated with a normal inflammatory response. In a similar equine study, the effect of Thorne Research Animal Health CurcuVET-EQ on mares and foals was found to have a positive impact on maintaining normal inflammatory responses. A recent human clinical study demonstrated that in more than 80 percent of patients with a long-term condition known to adversely affect ocular health, Meriva (the human equivalent of Thorne Research Animal Health CurcuVET-EQ) was well tolerated, reduced symptoms of eye discomfort, improved overall quality of life, and helped maintain the eye's normal inflammatory response.
Thorne Vet Honors the Human-Animal Bond
You only need to know one thing about the people who make up Thorne Vet: every one of them is passionately committed to healing animals.They deeply honor the bond between humans and animals. All of the people at Thorne Vet know and have experienced the emotional pain an owner feels when their animal is in a diseased state. They also understand the stress and obligation that you are under to help animals heal. Therefore, Thorne Vet's mission is to help the 50,000 veterinarians in private practice heal more animals, more effectively by providing you with the most potent, effective tools available.
How Thorne Vet Helps You Facilitate Animal Healing
Thorne knowa you are time challenged. Therefore, the fastest way they can help you get a quick understanding of the Purity-Healing Relationship is to simply look at a short list of what Thorne Vet considers to be ingredients that can negatively impact purity and thus the efficacy of a product.
Thorne Vet's foundation of healing is made up of 4 Essential Elements:
- Efficacy through Purity
- Healing through Science
- Transformation through Education
- Helping You Choose
Thorne's strict adherence to these four principles ensures that you and your clients will always receive the highest quality, most effective, bioavailable, and hypoallergenic animal health products in the world.
All of their innovative formulas are based on the latest scientific research and have been reviewed and tested by the most knowledgeable and experienced minds in our industry. You can prescribe Thorne Vet products knowing you are prescribing the best. Thorne Vet is seriously committed to supporting your efforts to heal animals, any way they can, even if you don't use one of their formulas.
Thorne Vet is Here For You and Your Animals
Thorne Vet is a unique organization committed to helping veterinarians heal animals more effectively through the use of integrative medicine. And to them this means so much more than producing the most innovative products on the market. They see themselves as your partner in the healing process.
Transformation through Education
At Thorne Vet, they understand all too well the challenges of trying to stay current on the latest research and advances in integrative veterinary medicine, while at the same time dealing with the day to day stressors of running your practice.
Their commitment at Thorne Vet is to continually develop ways to assist you not only to stay up to date on the latest knowledge in integrative veterinary medicine, but also to make it easy for you to access, assimilate and utilize this vital knowledge.
Healing through Science
As practicing veterinarians, all have experienced the challenge of what was found to have worked in the lab does not always translate into healing in practice. This is why all of Thorne's pure, highly bioavailable formulas are based not only on the latest scientific and medical research but before Thorne Vet formulas go to market they are passed through the knowledge filter and experience base of the top thought leaders in our field. In addition, they make this research easily available to you.
Helping You Make the Right Choice
Thorne Vet knows that finding the most effective products on the market can be time-consuming and challenging. Therefore, you can contact them anytime, and they will help you find a product even if they don’t carry it. Why do they do this? Because helping you heal animals is their primary commitment.
The Purity Healing Relationship
At Thorne Vet we deeply value the importance of the Purity–Healing Relationship. They believe that once you comprehend this Purity-Healing link, you will significantly alter the criteria by which you choose products that support your ability to treat animals. Thorne Vet is committed to helping you learn more about how this vital Purity-Healing Relationship can help you heal more animals more successfully.
Thorne Research's Mission
At Thorne Research, their mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity - thereby creating the most respected and valued company in the dietary supplement industry.
The Thorne Difference.
For more than 25 years, Thorne has relentlessly pursued the highest possible quality and bioavailability in dietary supplements. At Thorne, they actually manufacture products that they sell - a key difference that allows Thorne to control every aspect of the manufacturing process and ensure that every Thorne product is in pure, completely hypoallergenic form, and without the common additives, flowing agents, and binders used throughout the industry.
A few other companies have tried to do what Thorne does, and many others claim to have the same philosophy and quality, but nobody has been able to duplicate what Thorne's clients call "Thorne Quality." Thorne has changed the industry in many ways over the past two decades, and they continue to raise the bar and set new standards in product formulation, raw material purity, manufacturing, and quality control.
Thorne's Commitment to Purity
Practitioners have become accustomed to seeing the vague "We use only the purest ingredients" in the promotional materials of almost every dietary supplement company. Perhaps these companies truly believe that. Perhaps they don't know any better. Nevertheless, Thorne Research, for more than 25 years, has been the standard by which companies in the industry are judged for product purity. Practitioners rely on Thorne as the companythey trust for their extremely allergic, chemically sensitive, and immune-compromised patients.
Purity Takes Extra Effort
For example, instead of purchasing prediluted vitamin D, as other companies do, Thorne performs its own dilution to avoid detrimental ingredients, such as the preservatives or lactose that are found in many commercially available dilutions.
Ingredients You Don't Want
Magnesium Stearate: Good for speed-hungry encapsulating machines. Not necessarily good for you. Manufacturing encapsulated dietary supplements isn't easy. Pure powdered ingredients are difficult to mix because they are eitherextremely dry, sticky with botanical oils, or attract unwanted moisture. So most manufacturers add magnesium stearate and other agents such as lactose and dextrose to make the powder flow quickly and easily through their high-volume machines. Problem is, these additives may compromise the bioavailability of the nutrients in the supplement, and might cause allergenic problems. At Thorne, they take a different approach.
Thorne will never utilize large fatty acid excipients in its manufacturing processes - ingredients such as magnesium stearate or stearic acid. These excipients are utilized as flowing agents to ensure that maximum productivity is obtained from capsuling and tableting machines. There are documented detrimental effects directly attributed to long chain fatty acids utilized as manufacturing flowing agents. Every qualified pharmaceutical compounder recognizes that large fatty acids, such as magnesium stearate, can interfere with product dissolution and influence absorption. Virtually all companies, because of the economic impact, ignore this data. As with most industries, the bottom line dictates the level of quality. The dietary supplement industry has one exception: Thorne Research, the company that does not compromise. Nevertheless, if a company cannot manufacture products without using detrimental excipients, they should not allude to being either "hypoallergenic" or "pure."
The Bottom Line?
Thorne is the only hypoallergenic dietary supplement manufacturer with the highest degree of purity that you - and your most severely allergic, chemically sensitive, and immune-compromised patients - can truly trust.
Quality Ingredients: A Higher Standard
At Thorne, theyare committed to setting a higher standard of quality when it comes to ingredients. To produce their truly hypoallergenic encapsulated supplements, Thorne uses only the purest and finest ingredients available.
Every manufacturer has two basic options when purchasing raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. This fundamental dilemma translates to these very typical questions: "Do I purchase pure vitamin C or vitamin C with additives?" "Do I purchase pure B vitamins or coated B vitamins for taste masking?" "Do I purchase pure enzymes such as pancreatin, pepsin, and bromelain or enzymes diluted with lactose?"
There are few commercial sources for vitamins B12, D, K, or biotin that are not diluted with substances such as lactose, cornstarch, and preservatives such as BHT. That's why Thorne developed methods that allow them to use pure, undiluted sources of these nutrients - and many others. It's just one more example that when it comes to quality, what everyone else accepts as an industry standard isn't good enough. While some companies say they are raising their standards....at Thorne they set them.