TryptoPure L-Tryptophan by Life Extension
Life Extension TryptoPure L-Tryptophan 500 mg. Capsules
When tryptophan is ingested as a food or supplement, it is naturally degraded by specialized enzymes in the body. The problem is activity of one of these enzymes increases with age thereby denying the brain the tryptophan it needs to produce adequate serotonin. The result of the excess degradation of tryptophan can be seen in serotonin-associated troubles, such as:
There are three potential fates for L-tryptophan once ingested:
- Poor sleep quality
- Emotional mood and stress
- Weight gain and appetite
- Loss of feeling of well-being
- Incorporation into body tissue proteins.
- Conversion into serotonin (and melatonin).
- Conversion into indoleamines, carbon dioxide, water, adenosine triphosphate (ATP), and niacin
The degradation of tryptophan in the body can be inhibited with the intelligent use of other nutrients. For instance, the amino acid lysine competes with tryptophan in the same oxidative degradation pathway. This means that in the presence of sufficient lysine, less tryptophan is broken down through oxidation. Supplementation with nicotinamide has also been shown to spare plasma L-tryptophan from oxidation through the major pathway, permitting more plasma L-tryptophan to be available for conversion into serotonin.
The primary tryptophan-degrading enzyme is overactivated by inflammatory cytokines. The most comprehensive way to help prevent the enzymatic degradation of tryptophan thus is to suppress the inflammatory factors by taking the proper dose of extracts from ginger, hops, and rosemary.
A patent-pending formula called Optimized TryptoPure® Plus has been developed to protect tryptophan against excessive degradation in our aging bodies, thus sparing it for conversion into serotonin in the brain. Lysine, niacinamide, hops, ginger, and rosemary extracts have been shown to help the body utilize tryptophan more efficiently.
The Optimized TryptoPure Plus formula contains tryptophan that is certified pure enough to be used as an active ingredient in pharmaceutical products. This pharmaceutical-grade L-tryptophan costs more than other tryptophan raw material as it undergoes significantly more rigorous manufacturing processes to safeguard purity.
Life Extension is a global authority on nutrition, health and wellness as well as a provider of scientific information on anti-aging supplements and therapies. Life Extension supplies only the highest quality nutritional supplements, including minerals, vitamins, herbs and hormones.
Take one capsule one to three times daily, or as recommended by a healthcare practitioner.
For maximum absorption, take with six to eight ounces. of water or a small amount of carbohydrate such as diluted juice.
Take separately from food or supplements containing protein or amino acids.
Vitamin B6 is an essential cofactor in the conversion of L-tryptophan to serotonin in the body, while niacinamide plays an important role in enabling the body to properly utilize amino acids like tryptophan. Therefore, those taking L-tryptophan may find optimal results by consuming a B-complex supplement during the day that provides at least 50 mg of niacinamide and 50 mg of vitamin B6.
Serotonin syndrome is characterized by high levels of serotonin and symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not take L-tryptophan if you experience these symptoms. Do not take L-tryptophan in combination with other agents that increase serotonin levels in the central nervous system. Agents that increase serotonin levels can include psychiatric medications (e.g., antidepressants, lithium), migraine medications (e.g., sumatriptan), Parkinsons disease medications (e.g., carbidopa), and dextromethrphan, an over-the-counter cough suppressant. Do not use before driving or operating heavy machinery.
Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. If you have a bad reaction to the product, discontinue use immediately. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition, or if you are pregnant or lactating.
About Life Extension
Life Extension was officially incorporated in 1980, but the founders have been involved in anti-aging research since the 1960's. Their long-range goal is to extend the healthy human lifespan. Life Extension supply only the highest quality nutritional supplements, including minerals, vitamins, herbs and hormones.
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