Douglas Laboratories Cardio-Stolix - 240 Vegetarian Capsules
Douglas Laboratories Cardio-Stolix is a novel blend of natural ingredients, including unique milk-derived tripeptides, grape seed extract, herbs, vitamins, minerals and amino acids designed to support the body’s natural blood pressure regulatory mechanism and maintain proper cardiovascular function. Cardio-Stolix may be a useful dietary supplement for individuals wishing to support cardiovascular function and support blood pressure already in the normal range.
The ingredients in Cardio-Stolix are designed to work synergistically to support already healthy blood pressure, vascular and circulatory function, and general cardiovascular health.AmealPeptide™ AmealPeptide is a combination of two bioactive tripeptides (Valyl-Prolyl-Proline and Isoleucyl-Prolyl-Proline) that support the body’s regulatory blood pressure mechanism. AmealPeptide is derived from a proprietary process involving the enzymatic hydrolysis of casein (milk protein). The hydrolyzed milk protein contains bioactive tri-peptides that are thought to play important roles by limiting the conversion of angiotensin I to angiotensin II caused by the body’s production of angiotensin converting enzyme (ACE), a key enzyme that regulates blood pressure. Angiotensin II is a vasopressor and can influence the kidney’s retention of water and salt. By maintaining a healthy conversion of angiotensin I to angiotensin II with use of AmealPeptide, healthy blood pressure can be regulated and maintained. Fourteen short term and long term human studies show that AmealPeptide can support this natural regulation of healthy blood pressure. MegaNatural BP Grape Seed Extract Grape seed extract is well regarded for the beneficial role it can play in cardiovascular and antioxidant health. MegaNatural BP Grape seed extract is different from other grape seed extracts and made by a novel, patented water extraction process that yields a high grade extract with a low molecular weight. Mega Natural BP extract contains over 90% proanthocyanidins. Proanthocyanidins are highly regarded for their strong antioxidant properties, and for their functions in supporting the body’s connective tissues and capillary blood vessel system. Mega Natural BP grape seed extract has shown in studies to be superior to other grape seed extracts in its ability to prevent LDL (low density lipid) cholesterol oxidation. Studies in humans also show it can support already healthy blood pressure levels, as well as maintaining normal arterial function and endothelium cell function. In one human study, patients with metabolic syndrome were given Mega Natural BP grape seed extract or placebo. This extract was found to support the patients’ blood pressure levels already within normal ranges, whereas the placebo showed no significant change.
The cardiotherapeutic properties of hawthorn are due to its high content of many biologically active flavonoid compounds, including anthocyanidins, proanthocyanidins, quercetin, vitexin, vitexin ramnoside, as well as catechin and epicatechin. Hawthorn extract has been shown in human as well as animal studies to improve circulation by dilating coronary blood vessels. Dilation of these blood vessels consequently increases blood, and thus oxygen supply to the heart. Components of hawthorn extract have also been demonstrated to regulate the effects of angiotensin-converting enzyme, thus supporting healthy blood vessel constriction. Arginine As a precursor of nitric oxide, L-arginine serves to help support the healthy function of blood vessels and vascular tissue. L-arginine is also required for the synthesis of creatine phosphate. Similar to adenosine triphosphate (ATP), creatine phosphate functions as a carrier of readily available energy for contractile work in muscles. Adequate reservoirs of creatine phosphate are necessary in muscle as an energy reserve for anaerobic activity.
Nattokinase is a serine endopeptidase consisting of 275 amino acids. Laboratory studies indicate that nattokinase possesses stronger fibrinolytic activity than other known enzymes. Fibrinolysis is a normal biological process and an important part of an organism’s ability to heal wounds and regulate blood clotting. Proper regulation of fibrinolysis can help maintain a healthy flow of blood through the vascular system and ensure that the body’s major organs are continually supplied by oxygen, nutrients and other necessary products for complete health. Coleus In its native India, coleus has been used in the ancient medical system of Ayurveda for centuries. Laboratory and clinical studies have documented several benefits of forskolin. Forskolin has cardiac inotropic properties in that it appears to help strengthen heart muscle contractability. Forskolin promotes vasodilation, thereby helping to support healthy peripheral vascular resistance. Compounds in coleus including, but not limited to, forskolin, provide further benefit to the cardiovascular system by supporting healthy platelet function. Forskolin has also been shown to promote bronchodilation, in part by helping to relax airway smooth muscles and by maintaining healthy histamine and leukotriene release. Vitamins, Minerals and Cardiovascular Function Homocysteinemia, or elevated plasma homocysteine, is quickly emerging as a major, independent risk factor of cardiovascular diseases. High plasma levels of homocysteine appear to injure the vasculature, impairing the functional abilities of endothelial and smooth muscle cells. Suboptimal intake of several B vitamins, renal failure, and genetic defects in homocysteine metabolism can all contribute to abnormal homocysteine levels. Production of cysteine from homocysteine requires two specific enzymes for which vitamin B6 is an essential coenzyme. Without adequate vitamin B6 available, homocysteine can not be metabolized into cysteine. The body can also rid itself of homocysteine by remethylating it to methionine. The primary route by which homocysteine is remethylated to methionine requires methyltetrahydrofolate as a methyl donor and vitamin B12 as a coenzyme. Methyltetrahy-drofolate is created in the body from dietary folic acid. Vitamin C (ascorbic acid) has numerous biological functions. Foremost, it is essential for the synthesis of collagen and lycosaminoglycans which are the building materials of all connective tissues, such as skin, blood vessels, tendons, joint cartilage and bone. Vitamin C is the required coenzyme for two groups of enzymes that catalyze the crosslinking of collagen fiberslysyl hydroxylases and prolyl hydroxylases. As such, vitamin C is essential for normal wound healing and capillary health. Vitamin C is among the most powerful antioxidants in humans and animals. It is a watersoluble, chain-breaking antioxidant that reacts directly with superoxide, hydroxyl radicals, and singlet oxygen. Laboratory studies show that vitamin C completely protects lipids in plasma and low-density lipoprotein (LDL) against atherogenic peroxidative damage. In addition, vitamin C interacts with glutathione and alpha-lipoic acid, and regenerates vitamin E. Magnesium plays an essential role in a wide range of fundamental cellular reactions. More than 300 enzymes require magnesium as a cofactor. Complexed with ATP, the main carrier of metabolic energy in the body, magnesium is essential for all biosynthetic processes, glycolysis, formation of c-AMP, energy-dependent membrane transport, trans-mission of genetic code for protein synthesis, and muscle function.
Trust Douglas Laboratories, The Choice Of Thousands Of Healthcare Practitioners For Over 50 Years.
Trust Douglas Laboratories for a partnership founded on a heritage of excellence. For more than 50 years, they have been at the forefront of the nutritional health industry, proudly researching, developing and manufacturing superior-quality, science-based dietary supplements to help people improve their health. Proudly earning the trust of thousands of healthcare professionals.
Trust Douglas Laboratories for best-in-class, science-based dietary supplements manufactured exclusively for healthcare professionals. They are proud to offer one of the largest and most innovative selections of over 600 premium-quality products and a comprehensive range of galenic forms (dosage and delivery), manufactured at GMP-compliant, state-of-the-art facilities.
Trust Douglas Laboratories for personalized, one-to-one consultation on the latest, most reliable science, for strategies on using nutritional health to complement your practice and for coaching to better advise your patients on the right supplements for them.
About Douglas Laboratories
Back in 1955, Sam Lioon, founded Douglas Laboratories on a simple promise: provide the highest quality nutritional supplements available with the highest level of personal service—anywhere. And with that promise began a legacy of leadership—and a never-ending quest to exceed their customers’ expectations to Raise the Standard for Nutrition and Wellness.
Today that legacy lives on as Douglas Laboratories proudly joins the Atrium Innovations group of companies. Atrium Innovations is an international company and global leader in the development, manufacturing, and marketing of dietary supplements, specialty fine chemicals, and active cosmetic ingredients.
Douglas Laboratories is supported by more than 300 Douglas Laboratories employees all dedicated to keeping the promise Sam made 50 years ago. Raising the Standard is more than a slogan—it’s a promise. As they enter their second half-century, Douglas Laboratories will continue to keep their promise to Raise the Standard with a custom approach to ytheir patients’ nutrition and wellness. With custom formulations ytheir patients can’t find anywhere else. Custom labels. Custom daily packs. And the industry’s largest and most innovative product line. And they’ll back up their promise with the kind of stringent criteria many other companies overlook, such as:
(cGMPs) current good manufacturing practices.
ISO 9001 Certification and ISO 17025 Accreditation of their laboratories.
The industry’s first fully electronic, bar code driven, paperless manufacturing system to pass the FDA’s rigorous audit. Their exclusive Veri-Match labeling system, ensures verification prior to production and release of ytheir products.
(SOPs) standard operating procedures.
VCP (Vendor Certification Program) ensures raw material safety and quality.
Experienced, on-staff Ph.D’s, utilizing three full-service laboratories, outfitted with the latest analytical equipment.
State-of-the-art manufacturing, including ultra high-speed encapsulating machines, capable of producing over 35 million capsules and tablets daily!
Full compliance with the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, assuring safety and uninterrupted flow of all raw materials.
Douglas Laboratories continues to lead the way with clinical trials designed to validate the efficacy of their products. Their world-renowned Ultra-Preventive X (Ten) was rated the #1 multivitamin in the professional healthcare market, and their Vita-Big-Kids was rated the #1 children’s multivitamin overall by the independent Comparative Guide to Nutritional Supplements. Their commitment to help support patient outcomes is ongoing; look for their new in-office patient education posters, easy online ordering from their website and more innovative ideas designed to help ytheir practice grow in the days ahead.
But most of all, they’re proud of the many long-standing relationships they’ve enjoyed with so many customers over the years, and the many great friendships they’ve made along the way. It’s not an exaggeration to say that they truly enjoy what they do, enjoy coming to work each and every day.
**California Prop 65 WARNING: This product contains lead, a chemical known to the State of California to cause birth defects or other reproductive harm.**