Promera Health - Con-Cret Creatine Micro-Dosing 750 mg. - 72 Capsules
CON-CRET is a pure, concentrated, creatine hydrochloride designed for serious athletes (both professional and amateur) and any fitness-oriented person who is looking to increase their conditioning level or gain a competitive advantage. CON-CRET is also ideal for anyone whose livelihood may benefit from an increase in the production of Adenosine Triphosphate (ATP), a major source of energy or fuel for cellular and muscular function, such as those on restrictive diets and who are not getting enough creatine in the foods they eat.
Unlike other creatines on the market, CON-CRET does not require a loading phase or the need to cycle-off. Due to its bioavailability and recommended creatine Micro-Dosing , only a ¼ tsp (or 1 capsule) is needed per 100 lbs of body weight. A true scientific breakthrough, CON-CRET is the only creatine on the market that you dose by body weight, with one serving being equivalent to 5-10 grams of creatine monohydrate. Unlike other creatines, CON-CRET does not cause any negative side effects, such as bloating, water retention and GI issues that most have experienced from taking other creatine blends. In a recent creatine uptake study conducted by two major Universities, CON-CRET proved to be extremely soluble creatine on the market—59x more soluble than creatine monohydrate.
The most readily absorbed creatine form available, CON-CRET offers steroid-like results in strength, endurance and muscle recovery in a legal and safe natural product. Athletes can take CON-CRET and get superior results in performance without any worries of failing any form of drug testing – you will never be tested positive for any illegal or banned substances when taking CON-CRET.
Frequently Asked Questions
What is CON-CRET?
CON-CRET is the world's first and only pure creatine hydrochloride that delivers safe and effective results with no negative side effects typical of other creatines (such as bloating, cramping, GI issues, water retention, etc). Due to its unique Micro-Dosing, it's the only creatine that is dosed per body weight — ¼ teaspoon per (1 scoop or 1 capsule) per 100 lbs of body weight.
CON-CRET is a concentrated creatine hydrochloride molecule that has been proven to be the most potent and soluble creatine on the market. Creatines vary in performance largely based on solubility. The reason solubility is crucial – if creatine isn't in a solution form, it will not be absorbed into the bloodstream. In a recent study conducted by researchers from two major Universities, results showed convincing evidence of a significant improvement in plasma uptake concentrations of this creatine hydrochloride, CON-CRET — up to 70% greater —as compared to creatine monohydrate (CM) and other creatine blends.
CON-CRET is the most readily absorbed creatine form available and therefore does not require loading of large amounts or cycling off. CON-CRET's Micro-Dosing provides dramatic performance improvements in strength, endurance and muscle recovery, and is safe to take every day. Available in powder and capsule forms, each serving of CON-CRET is equivalent to the potency of 5-10 grams of creatine monohydrate.
What is Creatine?
Creatine is nitrogenous organic acid which naturally occurs in vertebrates and helps to supply energy to muscle and nerve cells. Creatine was identified in 1832 when Michel Eugène Chevreul discovered it as a component of skeletal muscle which he later named creatine after the Greek word for flesh, Kreas. Creatine, by way of conversion to and from phosphocreatine, is present and functions in all vertebrates, as well as some invertebrates, in conjunction with the enzyme creatine kinase. A similar system based on arginine/phosphoarginine operates in many invertebrates via the action of Arginine Kinase. The presence of this energy buffer system keeps the ATP/ADP ratio high at subcellular places where ATP is needed, which ensures that the free energy of ATP remains high and minimizes the loss of adenosine nucleotides, which would cause cellular dysfunction.
In the human body, approximately half of the daily creatine is biosynthesized by the use of parts from three different amino acids - arginine, glycine, and methionine. The rest is taken in by alimentary sources mainly from fresh fish and meat. 95% of it is later stored in the skeletal muscles, with the rest in the brain, heart, testes, inner ear hair cells and other organs and cells.
When did creatine become a popularized form of supplementation?
Creatine supplements are amino aids used to increase high-intensity athletic performance. Though researchers have known of the use of creatine as an energy source by skeletal muscles since the beginning of the 20th century, they were popularized as a performance-enhancing supplement in 1992.
Do creatine ester products have less potency than creatine monohydrates?
No. In fact, esters usually have more potency because they are more readily bio-available. Esterfication increases potency by about 10x when compared to creatine monohydrate. CON-CRET, however, is a molecular development beyond esters and is significantly more potent than creatine monohydrate.
What is the best manner to evaluate potency when comparing CON-CRET (Micro-Dosing) to all other forms of creatine (powder, pills, tablets and liquids)?
In order to evaluate potency, you need to consider solubility, because creatine needs to dissolve to get into your bloodstream and into your cells for maximum performance. ProMera health commissioned Vireo Systems (a nutriceutical manufacturer) to examine the solubility of CON-CRET compared to creatine monohydrate (the most common form of creatine). The study conducted between Vireo Systems and a major university showed results demonstrating CON-CRET's far superior solubility, bio - availability and potency. In this trial, a series of tests were run to compare the solubility of creatine monohydrate to CON-CRET in pure water. Before performing the procedure, it was insured that as many variables as possible were held at a fixed point during the experiment, including water temperature, volume, scale calibration, dissolving time and filter weight. To perform these tests, amounts of each compound were recorded and were given a set time to dissolve in water, and then were immediately filtered. Any precipitate left in the 100 ml of water was secured in the filter and dried. Once dry, the solid was weighed, and by assessing the difference of solid amounts, an estimate of solubility was calculated.
The results showed that the creatine monohydrate solution revealed 3.5 grams of the original 5.0 grams which was recovered un-dissolved, resulting in a solubility of 0.015 g/ml of creatine monohydrate, In comparison, 1.2 grams of CON-CRET was recovered out of a full 90.0 grams of the creatine, which resulted in a solubility of 0.888 g/ml of CON-CRET. This proves that CON-CRET is 59X more soluble than creatine monohydrate.
Since the human body is largely an aqueous based organism, these results predict a dramatic difference in the bio-availability between various conjugated dosage forms of oral creatine. Professionals in the health and medical community concur that solubility is one of the keys for mechanisms of actions to allow the uptake of molecules into the body. The following graph depicts the results of this study showing CON-CRET at nearly 59 times more potent than creatine monohydrate.
What amount of creatine is considered normal in a 200-pound person?
In light of the plethora of information put in the market by various vendors to support their products in terms of what should be "loaded" and then "maintained," from a creatine in-take perspective, what follows is a breakdown of what a typical 200 pound person should consider:
- This person has approximately 160 grams of "free" creatine in their body at any point in time, and is burning about 2.5 grams of free creatine per day.
- The body produces approximately 1 gram of creatine per day on its own.
- The body then needs the balance of 1.5 grams of creatine per day via diet or Supplementation.
- More activity/exercise can cause more creatine to be used and therefore needed.
Given the inefficiency, or put another way, the lack of potency associated with the various creatine products on the market today, it forces these vendors to hype heavy in-take during loading periods. In essence, it is their admission to their own products' lack of potency and a marketing ploy to increase usage/dosage, thereby increasing overall demand. CON-CRET does not require loading, nor does it need to be cycled-off, but instead with its unique Creatine Micro-Dosing (¼ tsp or 1 capsule per 100 lbs of body weight) there are no negative side effects typical of other creatine products that require massive in-take.
As a result of its overall potency and the efficiency of a unique creatine hydrochloride molecule, CON-CRET eliminates the need for ingesting massive quantities of powders and pills. One serving of CON-CRET is equivalent to the potency of 5-10 grams of creatine monohydrate, and once again there are no side effects (cramping, bloating, GI stress, and diarrhea).
How many grams of creatine are in a serving of CON-CRET (on an equivalent basis)?
CON-CRET is the only creatine on the market that is dosed based on body weight (Micro-Dosing). You receive superior results from smaller doses with no negative side effects. This Micro-Dosing approach calls for ¼ teaspoon (1 scoop or 1 capsule) of CON-CRET for every 100-pounds of body-weight.
As mentioned above, a single dose, or ¼ teaspoon of CON-CRET (0.8 grams per serving) is the equivalent in muscle cell potency to 5–10 grams of creatine monohydrate.
Do you recommend stacking CON-CRET with other supplements?
Generally speaking, CON-CRET can be stacked with complementary supplements. For example, stacking with whey or protein-based supplements is fairly typical and allows the user to benefit from the unique qualities each of these supplements offers. They would, however, discourage anyone from stacking CON-CRET with another creatine-based product, or with a product that does not fully disclose their ingredients list.
In developing CON-CRET, was the goal to eliminate the typical negative side-effects associated with other creatines on the market?
No. It was not the initial goal. In fact, their development team was focused on increased absorption. In achieving this goal and in-turn developing the Micro-Dosing approach, their team soon discovered that the overall efficiency of their solution eliminated these negative side effects when taken as directed they do realize, however, that not everyone shares the same metabolic process. As such, it is important to
see how you respond to the recommended dosage. If, for some reason, you do begin to experience negative side-effects, that is simply your body telling you to pull back on the dosage.
What is the main reason why CON-CRET does not produce negative side-effects?
As described above, it is the combination of small dosage amounts coupled with the overall efficiency in the absorption of CON-CRET by the body. To put it simply, users do not typically see negative side-effects when taking CON-CRET because there isn't all the "waste" that remains from other creatines – waste that the body uncomfortably struggles to process (gas, bloating). As stated above, however, they recognize that not everyone is the same. If for some reason you begin to experience side-effects, it simply means you can further reduce the dosage amount.
Is creatinine the primary cause of side-effects?
No. The primary cause is related to the difficulty the body has with excreting large dosage forms of other creatine products and the edema (fluid redistribution) of creatine outside the muscle tissue.
Would you suggest that glucose / dextrose be combined with CON-CRET?
No, it is not necessary. Most individuals get plenty of sugar in their daily dietary intake. They only suggest taking CON-CRET with 4-6 ounces of grape or apple juice because, when mixed with these juices, it will create a pleasant tart taste.
Does taking CON-CRET with grape or apple juice create a glucose carrier to assist product delivery into the body's system as compared to simply taking it with water?
As a continuation of the question above, they suggest taking CON-CRET with grape or apple juice simply to help moderate the tartness of the product. They do not promote, nor do they make any claims regarding the concept of a glucose carrier approach. In fact, their test results show CON-CRET performing equally well regardless of the liquid in which it is dissolved.
What is the pH of CON-CRET? What is the pH of your stomach? What does pH have to do with bio-availability and absorption?
pH is a measure of the acidity or alkalinity of a solution. Aqueous solutions at 25°C with a pH less than seven are considered acidic, while those with a pH greater than seven are considered basic (alkaline). When a pH level is 7.0, it is defined as 'neutral' at 25°C because at this pH the concentration of H3O+ equals the concentration of OH- in pure water. pH is formally dependent upon the activity of hydronium ions (H3O+), but for very dilute solutions, the molarity of H3O+ may be used as a substitute with little loss of accuracy. (H+ is often used as a synonym for H3O+). Because pH is dependent on ionic activity, a property which cannot be measured easily or fully predicted theoretically, it is difficult to determine an accurate value for the pH of a solution. The pH reading of a solution is usually obtained by comparing unknown solutions to those of known pH.
With that said, a dose of CON-CRET in 4-6 ounces of a liquid (grape juice, apple juice or water) yields a pH of approximately 2.0, but it does vary with the volume of liquid in which it is dissolved. As shown in the graphic below, the stomach has a pH that can vary between 1.0 and 2.0. Bio-availability and absorption are effected by pH in that the gastro intestinal (GI) tract is accustomed to dealing with low pH materials and therefore requires no change or differentiated chemistry to process. Put another way, CON-CRET's low pH is symbiotic to the stomach and the cleaved molecules are a completely natural component of the GI tract. This alignment produces the exceptional bio-availability and absorption rates that have been proven by the superior results experienced by CON-CRET users.
How stable is CON-CRET in water / juice?
Results from tests sponsored by ProMera Health, LLC, the manufacturer and marketer of CON-CRET, have shown CON-CRET to be perfectly stable after 60-days in water. They are in the process of further testing these attributes and will update upon receipt of new data.
How important is it that CON-CRET dissolves completely in water?
While there are significant studies that examine the percentage of water in the human body, it is widely agreed that the typical male has approximately 69% of their body mass comprised of water. For females, this number is approximately 55% (due to the higher proportion of body fat). Obviously, water is a critical component of life, and instrumental in maintaining health and wellness. This data points directly to the significance of CON-CRET being soluble and stable in water. In a recent double-blind experiment, their independent researchers completely dissolved 90 grams of CON-CRET in 100mL of water (3.4 fluid ounces). The nearest competitor could only achieve 25 grams being dissolved, and even then there was slight sediment visual. From there, most other creatines on the market could only dissolve 1 gram of product – clearly indicative of their lack of effectiveness and thus the need for
Do you load or cycle with CON-CRET?
No. There is no need to load CON-CRET as it is highly soluble and highly potent. As such, it delivers creatine directly to the muscles in a manner that does not require the inefficient process known as loading. There is no need to cycle as CON-CRET safely delivers creatine on a consistent and efficient manner, which eliminates the need for cycling.
When can you expect to see results from CON-CRET?
Users often report an immediate impact on endurance and recovery. From a strength building and muscle size perspective, their user assessments (volunteers who dosed from 4 to 104 weeks) reflected that 95% of users saw results in the first four weeks of usage with the balance noting results by week five. It is important to note that continued use of CON-CRET is safe and will continue to positively impact endurance, recovery, strength and mass when taken as directed. Remember, by facilitating strengthand recovery, CON-CRET allows you to work-out longer and more effectively so that you can build more muscle. It also can help increase muscle volume by pulling water into the cells for protein synthesis, which, in turn, causes the muscles to be bigger.
Finally, there have been several companies that tout that their creatine products are "micronized" – what are they referring to?
Unfortunately, this term tends to be marketing hype. In most cases, the term micronized refers to the difference between using 80 mesh creatine monohydrate and 200 mesh creatine monohydrate. Or, put another way, it is simply ground-down and screened to a finer powder consistency which usually brings along a higher price tag with no significant increase in performance.
The Con-Cret powder's pleasant, tart taste is a direct result of its molecular structure being aligned with the pH of the body's digestive track and natural chemistry. This allows Con-Cret to be absorbed by the body more efficiently than other creatine molecules. The Con-Cret powder is readily dissolved in any liquid. Promera suggests, however, that you mix Con-Cret with 4-6 ounces of water or juice.
Con-Cret can be taken on an empty stomach or with food or mixed with protein. For best results, be sure to take Con-Cret one-hour before your work-out or competition. You will notice, however, that they only recommend a ¼ teaspoon (or 1 capsule) of Con-Cret per 100 lbs of body weight. This Creatine Micro-Dosing approach eliminates the need for loading huge quantities of powders. It also yields one of the best costs per daily-dose on the market today.
About ProMera Health
ProMera Health's position is to guarantee to you that all their products are safe, compliant and do not contain a banned or illegal ingredient. Their sports supplement CON-CRET creatine has been IOC profiled by Aegis Sciences, one of the top forensic drug doping labs in the country to ascertain product purity.
StayActiv, a natural pain and anti- inflammatory remedy is the result of over six years of clinical studies and research at two major Division 1 University Medical Centers as an alternative to NSAIDs (non-steroidal anti-inflammatory drugs).
Many companies in the supplements industry today are quick to market and do not take the time that is needed for quality control and testing of their products. Because of this haste it is the customers (athletes) who suffer and find their health and possibly their career/eligibility in jeopardy. In contrast to these practices, ProMera goes above and beyond the industry requirements to ensure that they are only delivering safe and effective products, their commitment to you, their customer.
ProMera Health's goal has one purpose, develop and deliver the finest products available in the sports nutrition and wellness markets - it is their mission and it is their passion. To stay true to their principles and their beliefs, ProMera chooses to only align themselves with companies and partners who share similar philosophies and practices in safety and compliancy. This is very important to them, as to ensure that they continue to offer only high-quality products that meet strict guidelines of safety, compliancy and efficacy.