Biotivia - Transmax TR (Timed Release) Trans-Resveratrol 500 mg. - 60 Tablets
Transmax TR - The miracle molecule just keeps getting better and better. After 24 months of trials and research, Biotivia has developed a unique new form of their already best selling supplement, Transmax. This 500mg time release supplement is packed with bio enhanced Resveratrol. The sustained release version was created after receiving huge demand from physicians and health professionals who were looking for a time release form of Resveratrol as a dosage option to complement the original Transmax.
Biotivia - Transmax TR (Timed Release) Trans-Resveratrol:
- Laboratory Grade
- Weight Management!
This means that people suffering from a wide-range of illnesses, can receive the same high quality and potency of Resveratrol ... over a sustained 12 hour period. This provides the benefits of a constant supply of Resveratrol in one's blood stream. It also means that those users who depend upon Resveratrol's ability to enhance mental concentration and acuity and physical endurance, such as students, athletes, physicians and other high stress professions who are looking for a more sustained release of the active ingredient, now can extend the effects of Transmax to 12 full hours.
Why are Transmax Bio Enhanced capsules and Transmax Time Release supplements dramatically more effective and a far better value than standard resveratrol supplements.
Superior manufacturing methods and advanced formulation technology mean that Biotivia resveratrol supplements are far more effective and a much better value than resveratrol supplements produced by less experienced companies using standard processing technology and processes.
Resveratrol is absorbed and converted into its active metabolites in three ways, via the liver, the lining of the small intestine and by the bacteria in the intestines. The resveratrol in standard resveratrol produced by companies without the patented technology utilised by Biotivia is destroyed by stomach acids and enzymes before it can reach the small and large intestines. Biotivia supplements are protected from this destruction by advanced processing technology and its patented time release system. Transmax resveratrol supplements are designed to prevent exposure to the digestive chemicals in the stomach. Consequently a much larger amount, up to 3 times as much, of the resveratrol in Biotivia supplements, is absorbed and converted into the critical resveratrol metabolites.
This is why Biotivia resveratrol supplements are far more effective and a much better value than resveratrol supplements produced by less experienced companies using standard processing technology and processes.
About Transmax TR
Biotivia, the leading Resveratrol manufacturer in the US and Europe, has developed a new sustained time release Resveratrol supplement which provides a unique dosage option not available in any other high potency resveratrol product. By utilizing a patented sustain release technology Biotivia has extended the activity of Transmax in the blood stream evenly over a period of 12 hours versus a half life for competitors' Resveratrol of about 20 minutes.
Since the study done by Dr. David Sinclair at Harvard in which mice fed Resveratrol lived 31% longer then the control mice fed a diet without Resveratrol. This so called 'miracle molecule' has been the subject of huge interest and study by the medical and scientific communities.
Biotivia has supported many of these animal and human trials with its Transmax supplement. In fact, Transmax has become the preferred resveratrol supplement by scientists and researchers investigating the health effects of resveratrol.
One of the issues noted in some of these studies is the relatively short half-life of Resveratrol in human blood and tissue, leading some scientists to conjecture that Resveratrol's therapeutic effectiveness against certain disorders may be limited by this factor. Biotivia addressed this challenge two years ago by developing a proprietary Resveratrol supplement which had more than double the half-life and the bio-availability of this unique nutrient in Transmax. This is one reason why Transmax is considered to be the gold standard in high potency resveratrol supplements.
Now the scientists at Biotivia, working in collaboration with scientists at its Italian affiliate near Milan, have gone one step further. They have developed a patented time release version of the Trans-Resveratrol molecule which extends the effective concentration of the anti-oxidant and longevity supplement from around 90 minutes to about 12 hours.
This breakthrough means that those people who are being prescribed Resveratrol by their health care professionals as a treatment for serious medical conditions can now benefit from a continuous even concentration of the Trans-Resveratrol isomer. Healthy people who are taking Resveratrol for its beneficial effects in terms of general health, energy, fitness and longevity my choose to continue using the original bio-enhanced version of Transmax.
As an example of a potentially ideal application of the sustained release version, Biotivia recently announced an agreement with the University of Ferrara to do human trials of its Transmax formulation on 20 Thalassemia patients at a hospital in Italy. If these trials prove successful Biotivia intends to offer this new sustained release version of Transmax to Thalasemmia patients worldwide at a sharply discounted price. This could mean that hundreds of thousands of patients may soon be able to reduce or eliminate the need for monthly blood transfusions and their reliance upon expensive and highly toxic drug treatments.
Transmax has had its potency, safety and capsule claims an internationally recognized and respected independent testing lab validation. This is the only truly independent supplement verification of quality, quantity and integrity ... and Biotivia came out top in their tests when compared to other Resveratrol suppliers.
Another unique benefit to our resveratrol is that it contains far less Emodin than other Resveratrol brands. High Emodin levels found in many other brands can cause cramping and diarrhea but Biotivia Resveratrol has a safe 1% or less in it compared to over 5%, and up to 15% in competing products. This insures you will not experience gastric distress with Transmax or any other Biotivia product.
Transmax is currently being used by more medical schools and universities in human clinical trials than all other supplement brands together. Our quality, integrity, purity and manufacturing expertise meet the rigid standards of these institutions.
A premium product can only come from a premium supplier. Experience, resources, and strict quality control matter. Biotivia is the original resveratrol supplement manufacturer, not a company that was formed by marketers just to take advantage of the publicity resveratrol has received over the past year. Biotivia harvests its own raw materials from organic sources, processes its products in its own CGMP and SFDA certified facilities and rigidly tests every bottle to ensure potency. Biotivia is also the only manufacturer to use a patented Oxygen scavenging packaging system to protect our Resveratrol supplements from destructive oxidation each time the bottle is opened. This guarantees you the highest bio-availability. This is why every year for the past five years Bioforte and Transmax have been the world's most popular resveratrol supplements.
Transmax has many amazing heath benefits. These are to name but a few:
- Feel more energy, both mentally and phyiscally
- Increases stamina
- Increases mental ability
- Reduces appetite and cravings
- Helps to give a better sleep
- Lowers blood sugar
- Anti-aging qualities
- Cardio vascular protection
- Supports healthy arteries
- Incredible anti-oxidant properties
- Prevents oxidative damage from free-radicals
- Improves cell function
- Boosts immune system
- Increases metabolism
- Anti-inflamatory properties
- Faster and improved recovery time
- Eye protection
Why Choose Transmax Trans-Resveratrol Supplements
Transmax is the world's original and still best selling 500mg Resveratrol supplement, for good reasons.
Most other Resveratrol suppliers did not exist even two years ago. These new comers have sprung up to take advantage of the popularity of Resveratrol. Unlike Biotivia they have no experience processing critical botanicals such as resveratrol, no scientists, no in-house laboratory or quality control system and they simply buy raw material from the lowest price broker or middleman and fill generic capsules. One wonders what they are actually selling. Biotivia is a manufacturer of herbal products not simply a reseller. They have over 18 years as an international manufacturer and processor of quality rare botanical materials. They have the expertise, quality control systems, staff and experience to insure that their products meet rigid quality, quantity and potency standards. This is why they are the first choice of the medical and research communities when they require resveratrol for human studies and trials.
Sirt1-4 longevity genes activation is highly dose dependent. This is another example of their committment to product improvement through science. Bioforte is now being processed using a proprietary system which dramatically boosts Trans-Resveratrol Bio Availability. The result is a substantially more effective dietary supplement and a much better value.
Their products are the purest, highest-potency, best value and freshest quality-validated Resveratrol supplements available anywhere. It is that simple.
Real Effects You will Notice from the First Week
- Better Energy
- Reduced Appetite and Food Cravings
- Improved Mood
- Better Sleep
- Better Mental Concentration
A Company is Known by the Customers it Keeps.
Biotivia is not only the world's best selling Resveratrol product line, it is also the first and often only choice of major universities, research facilities and medical schools who buy their purified Resveratrol in the form of Transmax to conduct human studies and trials of Resveratrol's disease fighting and anti-aging properties. Their clients include such prestigious organizations as the Albert Einstein Medical School, Harvard University scientists and researchers, the US National Institutes of Health and the Health Ministries of Canada, the UK and many other countries. There are more human trials underway at major universities and medical schools using Transmax resveratrol than all other competitors' products together. Transmax is the only resveratrol supplement chosen by the US National Institutes of health and the Ministry of Health in Canada to certify as an investigational drug, IND. This is a tribute to the quality, integrity and potency of their Resveratrol health products.
The Transmax Trans-Resveratrol supplement provides the full daily dosage of the scientific trials in a single capsule.
Independent Verification of Biotivia's Quality sets apart from the pack
There is no substitute for truly independent validation of quality, purity, potency and safety. Bioforte is an internationally recognized and respected independent testing lab approved 250mg Trans-Resveratrol supplement and is the lowest cost per milligram supplement of all brands tested. An internationally recognized and respected independent testing lab results show that many brands of Resveratrol simply do not contain the amount of ingredients claimed on their label & ads and they make Bioforte's certificate of analysis available for you to view. Bioforte is 100% pure natural full-spectrum bio-enhanced Resveratrol. It contains no synthetic or genetically modified ingredients, no fillers and no Quercetin, Polysorbate, silica or other chemical
Frequently Asked Questions
How does Biotivia Achieve a Two Fold Increase in Bio-availability?
Biotivia scientists have extensively researched the pharmacokinetics of Resveratrol and have developed a first in class product. Other companies formulate Resveratrol with fillers and excipients or reduce particle size to support a claim of increased bio-availability. These suppliers have no scientific staff or laboratories and often base their formulations upon speculation by non scientists or data that are not relevant to Resveratrol. Biotivia tackles the root problem of the bio-availability of Resveratrol through research by their own scientists in their own research facilities and collaboration with respected university pharmacy schools.
How do they achieve enhanced bio-activity? Resveratrol goes through a step called phase I metabolism. Phase I metabolism takes place in your gut and actively attaches enzymes to Resveratrol to make it non-active. In the biotech industry companies combat this type of issue in two ways. The first is to use a pro-drug. A pro-drug, which can and often is a natural plant extract, is not active itself but gets degraded into the active drug, in their case Resveratrol. In essence this helps Resveratrol bypass phase I metabolism and increases the potency and efficacy of their products. Another common practice among biotech companies is to use a pharmacokinetic enhancer. A pharmacokinetic enhancer will allow more Resveratrol to enter your body and is an effective means of increasing Resveratrol's benefits.
The SirT1 activation properties of their resveratrol-based supplements are to a great extent a function of this enhancement process. The precise method and modifications to standard resveratrol used by Biotivia are trade secrets however in response to a challenge by one of their competitors, their claim of superior bio-avialability was upheld by the National Advertising Division of the National BBB after an extensive review of their evidence by their experts. Furthermore, an internationally recognized and respected independent testing lab found Transmax and Bioforte to be the two most potent supplements that passed their recent evaluation of Resveratrol brands. This is a test that most suppliers chose not to participate in. In their clinical research they have done a one to one human study of Transmax versus pure reference standard Resveratrol. They are confident that Biotivia offers truly unique and superior Resveratrol-based products in terms of effective potency and bio-availability.
What is the Difference Between Bioforte and Transmax?
Based on studies done to date virtually all of the benefits of Resveratrol derive from the Trans-Resveratrol isomer. Their Bioforte resveratrol supplement has 250mg of bio-enhanced "Trans-Resveratrol" per all vegetable Pfizer capsule. The remaining 250mg consists of the other forms of Resveratrol including glucosides of Resveratrol, polydatin, emodin and other beneficial compounds naturally found in the Polygonum Cuspidatum plant. That is why they call Bioforte their full spectrum Resveratrol product. Transmax resveratrol supplement contains 500mg of purified "Trans-Resveratrol" making it laboratory grade. None of their products contain fillers, inert ingredients, or extraneous chemicals which might interfere with the purity and effectiveness of their formulations. This is an important reason why Transmax and Bioforte are used by scientists, physicians and university researchers when trying to isolate and quantify the effects of Trans-Resveratrol in various trials and studies. Their buyers include the top research professionals from virtually all of the respected medical schools and research institutions in the US, including Harvard, MIT, Yale, Stanford, Georgetown, University of Pittsburg and many others in Europe and the Asia.
How Many Capsules Should I Take?
Dosage is a very individual choice and depends on your weight, metabolism, individual body chemistry and your primary reasons for taking the product. In general the amount you take should be in proportion to your weight. For example a 200 pound man should take roughly twice as much as a 100 pound woman, all other things being the same. If you are taking the product for a pre-existing condition then the dosage would be significantly higher than if you were taking Resveratrol as part of a preventative regimen. As part of a daily preventative regimen the average adult (i.e. 150 lbs.) should take 2 Bioforte or 1 Transmax dosage per day. This equates to about $1 per day for a Resveratrol supplement which has an extraordinarily wide range of benefits. If, however, you are treating a pre-existing condition many specialists would recommend a much higher dosage, say at least 4 times the preventative dose, or 4 Transmax a day.
When and How Should I Take the Product?
Resveratrol is not very water soluble therefore your body needs to produce enzymes such as bile from the liver and gall bladder to assimilate it. Therefore they recommend that you take our supplements along with or shortly after taking small amounts of an oily food. This stimulates the production of the necessary enzymes and facilitates absorption. Since their products are natural they can be taken on an empty stomach and will be absorbed more easily if taken at least one hour before or after consuming a substantial meal. Their supplements may be taken at any time however early morning is when your body best absorbs most nutrients. To prevent intracellular oxidation of the Resveratrol, and this applies to many other polyphenols as well, one should take an antioxidant with one's daily resveratrol dose. Although something as simple as one gram of Vitamin C will help prevent oxidation they naturally recommend that you consider Biotivia's Bio Quench super fruit extract formulation, as your choice of antioxidant. Bio Quench tested at an ORAC rating per gram of over 13,500. This is the highest rating for any dry compound ever tested by Brunswick Laboratories, the inventor of the ORAC test.
How Does Biotivia Protect against Oxidation and How Should I Store the Products?
Their products are very stable at room temperature but it will not hurt to refrigerate them. Either way they will last for at least 2 years on the shelf after opening. Only Biotivia utilizes a patented Active Packaging technology which captures the free oxygen which enters a bottle when a capsule is retrieved. This system prevent oxidation of the sensitive resveratrol isomer and insures that your product will be just as bio active two years from the purchase date as it is the day you buy it.
Biotivia Bioceuticals LLC Company Information
After 18 years of manufacturing raw materials and botanical extracts for the food, medical and supplement industries Biotivia entered the finished products arena for one reason. To design products that fit the space between generic vitamins and nutrients which are safe but only marginally effective, and prescription pharmaceuticals which are often effective but come with frequently serious adverse effects and high cost.
Unlike most supplement companies Biotivia was founded by and is staffed with scientists, pharmacists and specialists in nutraceuticals and botanical extract manufacturing. Their obsession is with quality, safety and effectiveness, not on compromising quality for the sake of a lower cost or on clever marketing gimmicks.
Their products are based upon intensive research and collaboration with the scientific and academic communities. They are safe, free of adverse side effects but uniquely potent and efficacious.
When they decide to create a new product they are guided by two overriding principals. First, there must exist a preponderance of definitive scientific evidence which demonstrates that a natural compound or combination of compounds has important health effects or efficacy against a medical condition, or can contribute to a significant improvement in a person's quality of life. Secondly, once their scientists have made this conclusion they identify the best product currently serving this application, if one exists, and they formulate their product to be at least one order of magnitude better.
The fact that they utilize only very high quality natural extracts, and they manufacture their products in sterile, regulated pharmaceutical facilities, and they take great care to preserve the integrity of the finished product means that their supplements will not always be the least expensive of their category. However they assure you that they will be ethical, efficacious, safe and based upon sound and rational design and formulation principals. We believe that good value is more than simply low price. Good value to us means a high quality, safe, effective product which is priced as low as they are able based upon their costs plus a profit sufficient to insure Biotivia remains economically viable.
Biotivia was established in 1992 in Vienna Austria as a supplier of natural raw materials and botanicals to the supplement and functional food industries and to researchers and scientific institutions worldwide. The company presently has US offices in New York, Los Angeles, Kansas City and international offices in the UK, Spain, Austria, Denmark, Italy, the Netherlands, Germany, Singapore, Xi'an China and Mumbai India.
Biotivia pioneered the science of supplement design and development based upon evidence of efficacy and safety drawn from the company's own studies and trials and in collaboration with world renowned research organizations. The company presently supplies researchers, physicians and scientists employed at Harvard, Stanford, Yale, Georgetown, The Albert Einstein Medical Center, University of Texas, the University of California, and many others with research-grade bioceuticals. Transmax and Bioforte are being studied by several major universities as a possible treatment for a variety of conditions that seriously impair the health and well being of millions of people around the world.
Biotivia is the first supplement manufacturer in the world to apply advanced "Active Packaging" technologies to its products to insure the highest level of freshness and potency even after the container is opened. It is also the first company to dramatically improve the bio availability of its products, especially its Resveratrol and polyphenol-based products. Low bioavailability of many antioxidants is a common problem which the company's scientists have succeeded in overcoming without resorting to synthetic additives or lowering the product dosage.
Biotivia's products are unique in their use of synergistic ingredient formulations which deliver outstanding potency and therefore greater efficacy and a better value to their customers. Bio Quench is an example of how evidence-based design works to increase product strength. The combination of trans-resveratrol and super fruit extracts in Bio Quench has resulted in achieving an ORAC value of over 13,500 units per gram, a new benchmark for super antioxidants.