Biotics Research Corporation has been a leading manufacturer of specially designed nutritional products for over thirty years. Our mission remains constant: to be the benchmark of excellence in nutritional science, technology and service, providing the clinician with reliable, innovative products of superior quality as well as the highest level of customer service.
Biotics Research Carbamide Plus provides special dietary support for healthy renal function. By providing nutrients that enhance the osmotic transfer of tissue fluids, Carbamide Plus supports the physiological elimination of water soluble waste products and promotes a healthy fluid balance in the body.
Carbamide Plus supplies USP grade carbamide, fortified with celery seed extract, Uva ursi, marshmallow and vitamin B6 (as pyridoxal-5-phosphate), in a base of Argizyme. Carbamide (urea), a water soluble, non-toxic substance, is produced in the liver, and is utilized by the body in a number of processes, primarily nitrogen excretion. It is synthesized by the body as part of the urea cycle. Besides its role of transporting nitrogen waste, carbamide plays a critical role in the re-absorption of water and key minerals from excreted urine. This mechanism is important for hydration and the maintenance of healthy blood pressure.
In addition to polyacetylenes and coumarins, celery seed extract supplies phthalide, a compound which relaxes smooth muscle in vessel walls, which in turn can have a positive impact on healthy blood pressure. Phthalide can also block the enzyme tyrosine hydroxylase, which is required for the production of stress hormones known to restrict blood vessels, and therefore blood flow. According to Dr. William J Elliot, Clinical Pharmacologist at U. of Chicago, celery is also a natural diuretic and decreases uric acid. Uva ursi, (Bearberry) functions as a natural diuretic.
Uva ursi supplies arbutin, a natural glycoside and the main active constituent. It is converted to hydroquinone, which is responsible for Uva ursi’s antiseptic properties. Marshmallow is included for its soothing properties and its ability to support healthy mucous membranes, due to its high mucilage content.
Vitamin B6 (as P-5-P) is a coenzyme for over 100 enzymes and is involved in a wide range of biochemical reactions. Among others, these include the synthesis of neurotransmitters, nucleic acids and hemoglobin, and the metabolism of amino acids. Vitamin B6 plays an active role in the immune system, and even a marginal deficiency may negatively impact both humoral and cell-mediated immune responses.
Why you may need Carbamide Plus: Despite their small size; only 4.5” long and weighing in at 4-6 ounces each, the kidneys are a remarkably important organ. In fact, they receive greater blood flow than the brain, the liver, or even the heart. All in all, they are responsible for redistributing and reabsorbing over 99% of the blood volume in the body. Over 26 million Americans over the age of 20 have chronic kidney disease, with diabetes being the leading cause, uncontrolled or poorly controlled blood pressure being the second leading cause. Healthy kidneys not only filter blood and regulate waste and toxins, but they maintain a healthy balance of the body’s fluid levels and regulate important hormones, including those that promote bone health, produce red blood cells, and those that regulate normal blood pressure. Therefore, maintaining optimal kidney health should be an important priority for overall health concerns.
Why your healthcare practitioner recommends Carbamide Plus: Carbamide Plus supplies USP grade carbamide, fortified with celery seed extract, Uva ursi, marshmallow, and vitamin B6, in a base of Argizyme. Carbamide (urea) is a water soluble, non-toxic substance that is naturally produced in the liver and is utilized in the body for a number of processes, most notably – nitrogen excretion. In addition to its role of transporting nitrogen waste, it plays a critical role in the re-absorption of water and key minerals from excreted urine. This mechanism is important for maintaining hydration and healthy blood pressure. Celery seed extract supplies polycetylenes, coumarins, and phtalide – a compound which not only relaxes smooth muscle in vessel walls (positively impacting blood pressure), but blocks the enzyme tyrosine hydroxylase, which is required for the production of stress hormones that are known to restrict blood vessels and blood flow. Uva ursi is a natural diuretic and antiseptic herb. Marshmallow is included for its soothing properties and its ability to support healthy mucous membranes. Vitamin B6 (as P-5-P) is a coenzyme for over 100 enzymes and is required for a wide range of biochemical reactions. These herbal extracts and nutrients are all supplied in a base of Argizyme, an enzymatically processed organic beet and Tillandsia (Silver Moss) formula that is rich in vitamins, minerals, amino acids, trace elements, and antioxidants.
All Bitoics Research Items are Gluten Free!
Currently, it is believed that gluten sensitivity (gluten intolerance) effects almost 700 million people
worldwide. Gluten intolerance covers a wide spectrum of conditions, including celiac disease and wheat allergy.
Symptoms include bloating, abdominal discomfort, pain, diarrhea, headaches and migraines, lethargy, attention-
deficit disorder, muscular disturbances, bone and joint pain, and even schizophrenia.
At Biotics Research, they provide superior nutritional supplements to benefit the patient health. ALL
BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE and they always have been! With Biotics Research, there's no
need to search through a catalog for all of the ingredients, or review label after label. You can use any product
from Biotics Research without concern because ALL BIOTICS RESEARCH PRODUCTS ARE GLUTEN FREE !
Quality Control - What Sets Biotics Apart
The Biotics Research way!
At Biotics Research Corporation, we manufacture our own branded products on site, in our own state
of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site
laboratories, the highly skilled members of our Quality Control Unit, utilize modern, sophisticated technologies
and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in-
process testing, and test all finished products prior to their release for shipment. In fact, many aspects of our
cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary
supplements in order to ensure the safety and effectiveness of our products.
The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures
associated with the production and release of all raw materials, packaging materials and finished products,
including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal
audits, and validates and audits all raw material and packaging suppliers and service vendors as well.
All incoming raw materials are subject to appropriate testing prior to their release for production. Tests
conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold
(including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of
all raw materials and finished products for future testing requirements (raw material stability and finished
product expiration date verification).
All bulk finished products (tablets & capsules) are inspected and subjected to metal detection
prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and
potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior
to packaging as well. Finally, microbiological testing is performed on all finished products and document
reconciliation is completed prior to being released for shipment.
All testing is performed by our trained QC personnel using state of the art laboratory instrumentation including
High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT
-IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC-
MS).
Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies
that are being regulated into implementing quality programs, extensive Quality Control has always been part of the
corporate fabric of Biotics Research Corporation.
From day one, the mantra of Biotics Research Corporation has been “Innovation and Quality.” Our goals remain
unchanged – utilize innovative ideas and carefully researched concepts with advanced techniques to develop products
of superior quality and effectiveness – bringing you “The Best of Science and Nature”.
Suggested Use
Three (3) capsules each day as a dietary supplement or as otherwise directed by a healthcare professional.
Warnings
Keep out of reach of children. Store in a cool, dry area. Sealed with an imprinted safety seal for your protection.
*Daily Value Not Established. †Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
Other Ingredients: Capsule shell (gelatin and water), cellulose, and magnesium stearate (vegetable source).
About Biotics Research
Biotics Research Corporation has been a leading manufacturer of specially designed nutritional products for over thirty years. Our mission remains constant: to be the benchmark of excellence in nutritional science, technology and service, providing the clinician with reliable, innovative products of superior quality as well as the highest level of customer service.
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