Life Extension - Advanced Anti-Adipocyte Formula - 60 Vegetarian Capsules
Life Extension Advanced Anti-Adipocyte Formula with AdipoStat and Integra-Lean African Mango Irvingia. If you’re struggling to maintain healthy body weight, you’re not alone. Up to 65% of Americans face the same challenge.1 Even a modest increase in fat pounds can have an impact on overall health, especially when it’s stubborn belly or visceral fat. The problem is that conventional methods to combat age-related changes that predispose to weight gain have proven ineffective. Adjustments in diet and lifestyle alone are often not enough.
Life Extension Advanced Anti-Adipocyte Formula Contains:
- No Milk
- No Egg
- No Fish
- No Peanuts
- No Crustacean
- No Shellfish
- No Soybeans
- No Tree Nuts
- No Wheat
- No Yeast
- No Gluten
- No Corn
- No Rice
- No Sugar
- No Artificial Sweeteners
- No Flavors
- No Colors
- No Preservatives
To help maturing individuals deal effectively with this serious health issue, Life Extension introduces a new, clinically validated solution: Advanced Anti-Adipocyte Formula with AdipoStat and Integra-Lean African Mango Irvingia. After careful scientific analysis of over 1,000 plant extracts, researchers identified the two species included in AdipoStat that target adipocytes: Sphaeranthus indicus flower and the mangosteen fruit (Garcinia mangostana). Optimal results were shown in studies when these two plant extracts were combined.
Through multiple pathways, AdipoStat targets the mechanisms by which fat-storing cells or adipocytes become bloated and metabolically dysfunctional. This widely overlooked cellular condition leads to excess fat accumulations in the belly and throughout the body.
AdipoStat functions via the following mechanisms to support healthy body weight:
- AdipoStat targets adipocyte (fat cell) creation.
- AdipoStat impedes adipocyte growth (adipogenesis).
- AdipoStat induces fat in adipocytes to break down (lipolysis).
AdipoStat’s performance in clinical studies indicates it can safely deliver impressive results. In a key study, 30 adults with difficulty maintaining healthy body weight ingested 800 milligrams per day of AdipoStat while following a 2,000 calorie per day diet and were asked to walk just 30 minutes five days a week. A group of equal size was given placebo. After just eight weeks, the AdipoStat group:
- Lost 4.05 inches of harmful belly fat—2.0 times the amount lost by the placebo group.
- Experienced a 2.05 drop in body mass index (BMI)—3.9 times over placebo.
- Shed 11.4 pounds of total body weight—3.7 times over placebo.
These improvements began to emerge after just 14 days. After eight weeks, the AdipoStat group saw a noticeable drop in waist-to-hip ratio, indicating they experienced fat loss in the abdominal area, where excess fat mass is associated with serious health issues. They also exhibited favorably elevated levels of a hormone called adiponectin.2 Adiponectin sends command signals that determine how big your fat cells get, how much they break down (lipolysis), and how often they are produced (adipogenesis).
A second human clinical trial yielded similar results, confirming AdipoStat’s beneficial effects.
There are two ways you can easily incorporate AdipoStat into your daily supplement program. The first option is to take Adipostat by itself. The second option enables consumers to obtain the same dose of AdipoStat along with the highly popular Integra-Lean (Irvingia gabonensis). Irvingia operates via additional mechanisms to combat surplus fat storage, including inhibition of glycerol-3-phosphate dehydrogenase, an enzyme involved in the conversion of glucose and triglycerides into adipocyte fat storage.
Frequently Asked Questions
What are Life Extension's quality control standards?
Life Extension uses only premium quality vitamins and other ingredients. Their dedication to excellence insists that their nutritional supplements meet the highest standards and criteria.
That is why Life Extension insists on purchasing only the highest quality raw materials from all over the world, primarily from leading US, Japanese and European sources. Life Extension goes one step further by using advanced analytical methods, such as high-performance liquid chromatography and gas chromatography/mass spectrometry, to ensure their products meet label claims for potency and purity. Life Extension tests its raw materials using US Pharmacopeia and other exacting pharmaceutical assay standards.
Why are Life Extension's nutritional supplements more advanced than other dietary supplements?
The unique ingredients included in Life Extension's products are often years ahead of the products sold by commercial vitamin companies. Life Extension scientists analyze thousands of scientific studies every week to make sure their health-promoting formulas include the most advanced life extending ingredients in the world. The Foundation interacts with the world's foremost gerontology researchers in order to obtain inside information about antiaging breakthroughs before these findings are published. The Life Extension Foundation funds the most advanced anti-ischemia laboratory in the world, where antioxidant vitamins, hormones, and pharmaceutical agents are used to prevent free radical induced cellular damage.
The most popular multivitamin supplement offered to Foundation members is Life Extension Mix.
The Life Extension Mix contains 92 unique vegetable, fruit, and herbal extracts along with high quantities of amino acids, vitamins, minerals, and special antioxidants. The Life Extension Mix formula is fortified with botanical extracts that help to maintain healthy cells via physiological processes separate from traditional antioxidants. Consumption of these types of plants is being recommended based on research emanating from the most prestigious medical centers in the world.
This 92 ingredient, super potent antioxidant formula is light years ahead of any multivitamin supplement on the market. Since 1983, Life Extension Mix has been reformulated 18 times to take advantage of scientific breakthroughs uncovered by Life Extension scientists. In 1985, the carotenoids lycopene and xanthophyll were added to Life Extension Mix. In1995, Life Extension Mix was reformulated to include even more potent extracts of lycopene and xanthophyll, along with a 22 to 1 broccoli concentrate and numerous other enhancements. In 2004, Life Extension Mix had the most extensive revision to date. The updated formula contains sesame lignans which have a broad range of applications in human health. This includes increasing human tissue levels of vitamin E by facilitating carrier proteins in the liver to deliver nutrients to cells throughout the body.
Chromium, magnesium and biotin are nutrients required to maintain optimal blood sugar levels. The updated Life Extension Mix provides 500 mcg of chromium (compared to 200 mcg in the previous version), a more absorbable form of magnesium, and the same high potency of biotin. A review of studies showing benefits for chromium supplementation revealed that doses exceeding 200 mcg a day are required for optimal effects. Life Extension Mix costs members less than other multinutrient formulas, which do not contain such nutrients as lycopene, xanthophyl (lutein extract), and broccoli.
Are your vitamins natural or synthetic?
Life Extension carries a combination of natural and synthetic vitamins and supplements. Some advertising statements would have us believe that "natural" is better, but natural supplements in some instances contain impurities such as pollen and naturally occurring hormones that can cause problems for some people. Synthetic nutrients are manufactured to be chemically identical (with the exception of vitamin E) to those extracted from natural sources, and are the most pure nutrient vitamins.
What does Life Extension do to ensure the quality of its products?
They focus on three specific areas.
- Raw Materials: Unlike other supplement companies, the natural ingredients that go into their supplements are not chosen based on cost. Instead they are chosen based on purity (to exclude contaminants such as microbes and heavy metals), potency, and usage in successful scientific research.
- Validation of the Efficacy of Ingredients by Scientific Research: They use ingredients and dosages that accurately replicate the most successful results obtained in scientific studies for maximum efficacy.
- Manufacturing: Naturally, they are in strict compliance with current Good Manufacturing Practice (GMP) for manufacturing, packaging, and storage.
Does the label accurately list exactly what’s in the bottle?
Yes. All active ingredients from patented, scientifically validated raw materials as well as final, finished products are verified using advanced analytical methods such as HPLC (high-performance liquid chromatography), MS (mass spectrometry), etc., to ensure each and every product accurately meets label claims in strict compliance with their demanding product specifications.
What are the “Other Ingredients” on the label, and why are they important?
They are inactive ingredients (excipients) that play a number of critical, essential roles in the manufacturing process including:
- Achieving uniform density for accurate dosing
- Dispersing the active ingredients evenly throughout a solid tablet, capsule, and softgel
- Protecting active ingredients from rapid inactivation due to heat and moisture
- Promoting tablet disintegration, as well as capsule and softgel dissolution
- Sustaining the release of active ingredients into the body over time
Why do some companies refer to these excipients as a threat to your health?
Claiming any product is “pure and free of excipients” can be deceptive advertising, too frequently used to draw attention away from inferior active ingredients! The right inactive ingredients used in the right way do important things … like ensuring that a tablet disintegrates in your GI tract rather than just passing through your system without benefit, or keeping a product from breaking down and being susceptible to microbes. Take Life Extension blueberry extract, for example. It contains Aurora Blue wild-harvested, Alaskan blueberries. To retain their nutritional complexity, these berries are freeze-dried and carefully milled for capsule formulation. But being a whole fruit raw material, it tends to want to reconstitute itself with moisture, which would make it a breeding ground for bacteria. So Life Extension uses a drying excipient to keep the milled blueberry material dry, so it can safely deliver its superior nutritional value compared with other, less costly blueberry extracts in most commercial formulations.
All of the excipients Life Extension uses have earned GRAS (“Generally Regarded As Safe”) status … and are used sparingly. In many cases not using them compromises final product quality! Excipients are used in nutritional supplements to ensure uniform density of complex active materials, to achieve even dispersion of active ingredients, and to promote appropriate disintegration and/or dissolution of active ingredients inside your body … to name but a few of the critical roles played by excipients.
Should I be concerned about the use of stearic acid?
Stearic acid functions as a flow agent in the manufacture of quality products, and stearic acid also occurs naturally in the foods you eat. For example, four ounces of dark chocolate contain 3,625 mg of stearic acid; a cup of kidney beans contains 1,655 mg of stearic acid; an ounce of raw ground beef (grass-fed) contains 2,063 mg of stearic acid; and a half pound of lean raw turkey contains 1,642 mg of stearic acid. Even a tablespoon of allspice contains 1,513 mg of stearic acid! their supplements, on the other hand, typically contain no more than 10 mg per capsule. They always use the lowest level of magnesium stearate possible.
Should I be concerned that products with soybean oil or lecithin are a source of phytoestrogens?
While it is true that soy isoflavones are phytoestrogens, the amount in soybean oil or lecithin is so minute, the USDA lists it in foods as having zero value for isoflavones. To give you a frame of reference, Life Extension’s Ultra Natural Prostate contains 4 mg of lecithin which supplies only about 0.006 mg of soy isoflavones!
Should I be concerned with the usage of genetically modified plants (GMOs)?
Soybeans are an example of a crop that has used extensive genetic engineering to increase crop yield. The reality is that soybean oil and soy lecithin are highly processed derivatives of soy … far removed from their soy origin. Genetic modification doesn’t alter the entire plant… only a specific gene. Thus, specific molecules like soy lecithin are the same whether they come from a GMO or non-GMO soy source. However, due to their sensitivity to customer concerns, products with corn and soy-based active ingredients are in process of having the labels updated to list when soy and corn-derived active ingredients have been certified to be from non-GM food crops. As the labels are updated the information will be transferred to the product descriptions on their website and directory. Currently Life Extension already offers several premium quality non-GMO soy isoflavone extract products.
Does the gelatin used in softgels and capsules contain MSG?
Gelatin does not contain MSG … but does contain about 0.05 grams of glutamic acid in one softgel. You ingest about 120 times more glutamic acid in a serving of asparagus, cabbage or tomatoes!
What’s the difference between tablets, capsules and softgels?
Sophisticated products require sophisticated delivery systems. The best companies choose the most effective finished form based on the characteristics of the raw materials, and the desired disintegration or dissolution characteristics of the finished product and the active ingredients.
Why aren’t Life Extension products organic?
The word “organic” conveys the perception of quality to consumers. But it actually relates to foods that are grown rather than products that are formulated. Many of their scientifically validated raw materials are not produced organically. Rather, their mandate includes rigorous testing and scrupulous processing. The objective is purity … both in terms of their raw materials and their finished products.
Life Extension's Vison
Their goal at Life Extension is to increase the quality and longevity of human life with science-based, “cutting edge” formulations. The unique ingredients included in Life Extension products are sometimes five to ten years ahead of the products sold by commercial vitamin companies.
Every week, Life Extension's in-house research staff analyzes thousands of scientific studies, reviews dozens of the world's leading peer-reviewed scientific, health, and medical journals, and interacts with leading anti-aging researchers to uncover the very latest breakthroughs as they relate to nutritional supplementation. This information is then passed on to their product development team which develops scientifically innovative, health-promoting formulations.
For over 25 years, Life Extension has developed nutritional supplements with the highest degree of quality, potency, and purity. Unlike discount supplement providers, Life Extension differentiates itself through quality, not price. Many discount products, for example, use low grade vitamin C imported from China that contains traces of arsenic, lead, and iron. Since the FDA does not believe anyone should take more than 100mg a day of vitamin C, the FDA permits the importation of this contaminated vitamin C. Many Life Extensionists take over 3,000 mg of vitamin C a day, so it is crucial that they use top-quality vitamin C that has gone through 18 purification steps to remove contaminants.
Life Extension’s complete line of nutritional supplements includes vitamins, minerals, amino acids, phyto-nutrients and standardized herbal concentrates.
Life Extension's Commitment to Scientific Research
Commercial companies have made huge profits on products such as coenzyme Q10, melatonin and DHEA, each of which was introduced to the U.S. market by Life Extension at considerable risk. Life Extension performed the research on these products, determined their validity and viability, and subsequently brought them to market based upon the strength of evidence behind them.
In the past seven years, Life Extension has funded over $21 million in research through their affiliations with such esteemed institutions as U.C. Berkeley and Mt. Sinai Medical Center. In 2004, Life Extension's scientists were awarded a $900,000 grant to continue their pioneering work, and they collaborated with BioMarker Pharmaceuticals and scientists at the National Cancer Institute to develop new anti-aging and anti-cancer therapies. This resulted in a recently accepted publication in the prestigious Proceedings of the National Academy of Sciences.
In addition, Life Extension has funded life span studies at the Universities of Wisconsin, California at Riverside, and Arkansas, gene transfer studies at the Gerontology Research Center in Baltimore, neurotransmitter studies to find the key to brain aging at the University of California at Berekely, and resveratrol studies BioMarker Pharmaceuticals in collaboration with Harvard Medical School and Critical Care Research.