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Doctor's Best
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About Doctor's Best

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.

Contact Doctor's Best

197 Avenida La Pata
San Clemente, CA, 92673
http://www.drbvitamins.com
949-498-3628

Doctor's Best - Best Acetyl-L-Carnitine Featuring Sigma Tau Carnitine 588 mg. - 60 CapsulesEnhances Alertness & Mental Focus!

Zoom View - Best Acetyl-L-Carnitine Featuring Sigma Tau Carnitine
Egg FreeWheat FreeSoy FreeGluten FreeDairy FreeSugar Free
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    Item Code: 71710
    UPC Code: 753950001053
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    Retail Price: $21.99
    LuckyVitamin: $13.99
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    Product: Best Acetyl-L-Carnitine Featuring Sigma Tau Carnitine
    Code#: Lucky ID: 71710 | UPC: 753950001053
    Manufacturer:Doctor's Best
    Size/Form: 60  Capsules
    Packaged Ship Weight: 1  lbs
    Servings: 60
    Dosage Size: 1  Capsule(s)
    Potency Size: 588  mg.
    Auto Re-Order Frequency: More Info



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    3 of 3 (100%) of customers said they would recommend
    this product to a friend.

    Description Suggested Use Ingredients Reviews Manufacturer Info Show All
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    Doctors Best - Best Acetyl-L-Carnitine 588 mg. - 60 Capsules

    Doctors Best Best Acetyl-L-Carnitine (ALC) is a naturally occurring form of L-Carnitine, a vitamin-like nutrient synthesized in the body from the amino acids lysine and methionine. ALC plays a key role in the production of acetylcholine, an important neurotransmitter for brain and nerve cell function.

    The Acetyl-L-Carnitine in this product is derived from a base of pharmaceutical grade L-Carnitine manufactured by patented, FDA-approved process that fully complies with the USP 25, FCC 4 and EU monographs. It is GMO-free, pesticide-free and BSE safe.

    Features & Benefits:

    • Science-Based Nutrition
    • Dietary supplement
    • Beneficial antioxidant protection
    • Enhances alertness and mental focus
    • Supports energy metabolism in the brain
    • Keeps nerves healthy and in repair
    • Decreases free radical production in the brain
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    Supports Cognitive Function
    ALC has been studied for its effect on cognitive performance and emotional health in the elderly. In a single-blind, placebo-controlled trial, 481 elderly subjects taking 1500 mg of ALC per day were found to have improved scores on a memory test assessing cognitive abilities after 90 days of ALC supplementation. In addition to being known for its effects on recognition and memory, placebo-controlled ALC research has also shown better scores in scales measuring the mood of elderly people.

    Supports Biosynthesis of Acetylcholine, a Key Neurotransmitter for Brain and Nerve Function
    Brain function requires coordinated communication between brain cells. Neurons (brain & nerve cells) communicate across tiny cell-to-cell gaps called synapses. The passage of an electrical impulse from one neuron to the next requires a neurotransmitter to act as a messenger to pass signals to adjacent neurons. When an electrical signal arrives at the synaptic junction, the neuron releases a neurotransmitter into the synapse. The neuron on the other side of the synapse contains receptors for the neurotransmitter (that will bind it), triggering a series of chemical events to send a new electrical signal down the membrane of the receiving neuron. Neurotransmitters work together like an orchestra to transmit information throughout the brain and nervous system.

    Acetylcholine is the most abundant neurotransmitter in the body, regulating activities of vital organs and blood vessels, and communication between nerves and muscles. In the brain, acetylcholine helps to facilitate memory and learning, as well as influencing emotions. ALC is structurally similar to acetylcholine— enough so that brain neurons stimulated by acetylcholine are receptive to stimulation by ALC. In an experimental animal model, it was shown that ALC can furnish acetyl groups to be utilized during the natural biosynthesis of acetylcholine. ALC’s structural similarity to acetylcholine has led researchers to investigate its effects on mental function and emotional health.

    Helps Supply the Brain With Energy Through Mitochondrial Efficiency
    The acetyl groups donated by ALC can be used to naturally synthesize acetyl-CoA, the key substrate for energy metabolism in the mitochondrion. Acetyl-CoA enters the Krebs cycle, the mitochondrial pathway that generates cellular energy in the form of ATP. Age-related decreases in mitochondrial oxidative capacity are a well-known cause of aging, as the organelles and organs in the body begin to operate less efficiently without ideal ATP production. The effects of decreased mitochondrial oxidative capacity are especially prevalent in organs that require high-energy inputs, such as the brain and heart. Recent clinical studies have shown that ALC helps to promote and maintain healthy mitochondrial function.

    Helps Uphold the Integrity of Intracellular Membranes
    Phospholipids are structural components of brain cell membranes that regulate neuronal function. ALC has been shown to promote healthy membrane phospholipid metabolism in research subjects. Additionally, the acetyl groups in ALC are naturally utilized by the body to modify the activity of proteins in neuronal membranes. Through these means, ALC promotes normal membrane function, stability, and structural integrity.

    Supports Nerve Growth Factor Production
    The body produces specialized proteins called growth factors that are essential to the growth and repair of tissue. Nerve Growth Factor (NGF) prolongs the survival of neurons in both the central and peripheral nervous systems. As we age, our central nervous system experiences a decrease in the binding of NGF to neuron membranes. ALC has shown the ability to promote the maintenance of normal interactions between NGF and neuron membranes. Given to aged rats, ALC demonstrated effectiveness in promoting normal levels of NGF, and it helped maintain utilization of the growth factor in the rats throughout the duration of the study. Maintaining ideal levels of NGF is essential for the health of cholinergic neurons (nerve cells stimulated by acetylcholine), as cholinergic neurons lose some functional capacity due to a lack of NGF. In aged rats, ALC is known to promote the health of cholinergic neurons. In sum, such results suggest that ALC positively influences the maintenance of healthy and normal NGF activity.

    Supports Healthy Brain Neuron Function
    Several animal studies have revealed that ALC contains many biochemical characteristics that help neurons face the aging process optimally. ALC has been shown to raise levels of glutathione, a key antioxidant, in isolated mouse brain tissue. ALC also reduces blood levels of MDA (malondialdehyde), a free radical byproduct. Furthermore, ALC is a chelator of iron: it acts as a molecule that can naturally sequester iron in the body to prevent iron-mediated oxidative damage to cells. As a whole, data from in vitro and animal studies suggest that ALC is effective towards the maintenance of healthy brain neurons and normal neuronal energetic processes. This hypothesis is supported by human studies that demonstrate the potential of ALC to promote healthy brain function in elderly persons.

    Suggested Use

    As a dietary supplement, take 1 to 4 capsules daily with or without food.

    Warnings

    ALC is considered safe and well tolerated when consumed orally. Taken as directed by the label, the maximum daily dosage of this product is 4 capsules per day, well within the limits reported by human safety studies of ALC using the Observed Safety Level (OSL) method.
    Ingredients

    Doctor's Best - Best Acetyl-L-Carnitine 588 mg. - 60 Capsules
    Supplement Facts
    Serving Size: 1 Capsule
    Servings Per Container: 60 Servings
    Amount Per Serving %DV*
    Acetyl-L-Carnitine
    (from 588mg acetyl-l-carnitine HCl supplied by Sigma tau)
    500 mg *
    *Daily Value Not Established.
    †Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
    Other Ingredients: stearic acid, cellulose, magnesium silicate, silicon dioxide, gelatin capsule.
    About Doctor's Best

    Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.


    197 Avenida La Pata
    San Clemente, CA, 92673
    Phone: 949-498-3628
    Fax: 949-498-3952
    http://www.drbvitamins.com
    Reviews
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    Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

    Average Customer Rating: (4 out of 5)

    Based on 3 rating(s)
    3 of 3 (100%) of customers said they would recommend this product to a friend.
    • By steven J ( Brunswick, ME)
      10/26/2011 7:45:23 AM

      I recommend this product!
      Havent used this long enough yet but diffinately seem to notice an extra fat burn. I will continue to use L -Carnitine.
    • By Oscar ( Elmhurst, NY)
      12/18/2012 10:53:08 PM

      I recommend this product!
      Very important for the body as it ages,,Acetyl-L-carnitine helps the body produce energy. It is important for heart and brain function, muscle movement, and many other body processes.,,its my daily take,,,great price.
    • By Donald C. ( Media, PA)
      10/21/2013 7:28:35 PM

      I recommend this product!
      This product appears to help.
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    *The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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