Nature's Plus Herbal Actives Extended Release Red Yeast Rice 600 Mg & CoQ10 100 Mg - 30 Vegetarian Tablets
Nature’s Plus Herbal Actives Extended Release Red Yeast Rice CoQ10 provides 100 mg pharmaceutical grade Coenzyme Q10 with the highest quality Red Yeast Rice extract, which is uniformly standardized to a minimum of 1.7% (10.2 mg) total monacolins and maximizes the synergistic benefits of the whole extract. Each Nature's Plus Red Yeast Rice CoQ10 tablet employs a revolutionary extended release system that provides rapid and sustained results.
Red Yeast Rice
Parts Used and Where Grown
This substance, native to China, is a fermentation by-product of cooked non-glutinous rice on which red yeast has been grown. The dried, powdered red yeast rice is used medicinally.
Historical or Traditional Use
Since 800 A.D., red yeast rice has been employed by the Chinese as both a food and a medicinal agent. Its therapeutic benefits as both a promoter of blood circulation and a digestive stimulant were first noted in the traditional Chinese pharmacopoeia, Ben Cao Gang Mu-Dan Shi Bu Yi, during the Ming Dynasty (1368–1644). Practitioners of Traditional Chinese Medicine use red yeast rice to treat abdominal pain due to stagnant blood and dysentery, as well as external and internal trauma. In addition to its therapeutic applications, red yeast rice has been used for centuries as a flavor enhancer, a food preservative, and a base for a Taiwanese alcoholic rice-wine beverage.
In addition to rice starch, protein, fiber, sterols, and fatty acids, red yeast rice contains numerous active constituents, including monacolin K, dihydromonacolin, and monacolin I to VI.
Researchers have determined that one of the ingredients in red yeast rice, called monacolin K, inhibits the production of cholesterol by stopping the action of a key enzyme in the liver (e.g., HMG-CoA reductase) that is responsible for manufacturing cholesterol. The drug lovastatin (Mevacor) acts in a similar fashion to this red yeast rice ingredient. However, the amount per volume of monacolin K in red yeast rice is small (0.2% per 5 mg) when compared to the 20–40 mg of lovastatin available as a prescription drug. This has prompted researchers to suggest that red yeast rice may have other ingredients, such as sterols, that might also contribute to lowering cholesterol.
Along with its evaluation in animal trials, red yeast rice has been clinically investigated as a therapy for reducing cholesterol in two human trials. In one trial, both men and women taking 1.2 grams (approximately 13.5 mg total monacolins) of a concentrated red yeast rice extract per day for two months had significant decreases in serum cholesterol levels. In addition, people taking red yeast rice had a significant increase in HDL (“good”) cholesterol and a decrease in LDL (“bad”) cholesterol. Elevated triglycerides were also found to be lowered.
A double-blind trial at the UCLA School of Medicine determined that red yeast rice in the amount of 2.4 grams per day (approximately 10 mg total monacolins) in capsules significantly decreased total- and LDL-cholesterol levels in a sample of people with elevated cholesterol after 12 weeks of therapy. Triglycerides were also reduced in those taking red yeast rice. However, unlike the original study, HDL values did not increase substantially.
How Much is Usually Taken?
The red yeast rice used in various studies was a proprietary product called Cholestin, which contains ten different monacolins. The amount of Cholestin used in these studies was 1.2–2.4 grams (5–10 mg of monacolins) per day in divided amounts for 8-12 weeks.
Note: Cholestin has been banned in the United States, as a result of a lawsuit alleging patent infringement.
Other red yeast rice products currently on the market differ from Cholestin in their chemical makeup. None contain the full complement of ten monacolin compounds that are present in Cholestin, and some contain a potentially toxic fermentation product called citrinin. Despite these concerns, other red yeast rice products are being widely used and anecdotal reports suggest that they have a similar safety and efficacy profile as that of Cholestin.
Are there any side effects or interactions?
The Cholestin brand of red yeast rice has been generally well tolerated with possible temporary mild side effects such as heartburn, gas, and dizziness. This product should not be used by people with liver disorders and its safety during pregnancy has not been established. As in the case of medications that inhibit HMG-CoA, it is advisable that people using red yeast rice products also supplement 30–60 mg of coenzyme Q10 daily.
There is one case report of muscle weakness and joint pain occurring in a man who was taking red yeast rice. Because the man was also taking several prescription drugs, it was not clear whether the symptoms were caused by red yeast rice. In another case report, a woman developed severe muscle pain with laboratory evidence of muscle damage while taking red yeast rice. In that case, red yeast rice appeared to be the cause of the muscle damage. These reports should be taken seriously, because muscle problems are common side effects of prescription HMG CoA-reductase inhibitors.
There is one case report of hepatitis developing in a woman taking red yeast rice. She was also taking two medications that have been reported to cause hepatitis, so a cause-effect relationship with red yeast rice was not proven. However, since statin drugs have been reported to cause hepatitis, it is possible that this complication can also result from taking red yeast rice.
Are there any drug interactions?
Certain medicines may interact with red yeast rice.
Coenzyme Q10 (CoQ10) is also called ubiquinone, a name that signifies its ubiquitous (widespread) distribution in the human body. CoQ10 is used by the body to transform food into adenosine triphosphate (ATP), the energy on which the body runs.
Where is it found?
CoQ10 is found primarily in fish and meat, but the amounts in food are far less than what can be obtained from supplements.
Who is likely to be deficient?
Deficiency is poorly understood, but it may be caused by synthesis problems in the body rather than an insufficiency in the diet. Low blood levels have been reported in people with heart failure, cardiomyopathy, gingivitis (inflammation of the gums), morbid obesity, hypertension, muscular dystrophy, diabetes, AIDS, and in some people on kidney dialysis. People with phenylketonuria (PKU) may be deficient in CoQ10 because of dietary restrictions. CoQ10 levels are also generally lower in older people. The test used to assess CoQ10 status is not routinely available from medical laboratories.
Which form of coenzyme Q10 is best?
Some, but not all, research suggests that a fat-soluble form of CoQ10 is absorbed better than CoQ10 in granular (powder) form.
How much is usually taken?
Adult levels of supplementation are usually 30–90 mg per day, although people with specific health conditions may supplement with higher levels (with the involvement of a physician). Most of the research on heart conditions has used 90–150 mg of CoQ10 per day. People with cancer who consider taking much higher amounts should discuss this issue with a doctor before supplementing. There are several anecdotal reports of large amounts of CoQ10 resulting in improvements in certain types of cancer. However, controlled trials are needed to confirm these preliminary observations. Most doctors recommend that CoQ10 be taken with meals to improve absorption.
Are there any side effects or interactions?
Congestive heart failure patients who are taking CoQ10 should not discontinue taking CoQ10 supplements unless under the supervision of a doctor.
An isolated test tube study reported that the anticancer effect of a certain cholesterol-lowering drug was blocked by addition of CoQ10. So far, experts in the field have put little stock in this report because its results have not yet been confirmed in animal, human, or even other test tube studies. The drug used in the test tube is not used to treat cancer, and preliminary information regarding the use of high amounts of CoQ10 in humans suggests the possibility of anticancer activity.
Are there any drug interactions?
Certain medicines may interact with coenzyme Q10.
Herbal Actives from Nature's Plus
The Nature's Plus Herbal Actives line of herbal supplements and vitamins are the most complete line of powerful standardized herbal formulas ever developed! Many ancient civilizations used health-promoting native plants, botanicals and trees, but more than any other, Chinese and Ayurvedic health traditions have continued from generation to generation.
Herbal Actives draws on this rich tradition of natural health-promoting botanicals to create standardized top-quality herbal supplements and vitamins, enhanced and empowered with the latest herbal research and technology. Millions of consumers around the world rely on Herbal Actives to support their goals for health and well-being.
The extensive line of Herbal Actives herbal supplements and vitamins consists of the most sought-after herbal products on the market, including: Echinacea, goldenseal, St. John's Wort, ginkgo biloba, Korean ginseng, pomegranate, valerian, red yeast rice, super fruits, green tea, milk thistle
...plus over 100 of the finest herbal supplements and vitamins!
The Nature's Plus standards of excellence in quality manufacturing practices guarantees products that exceed industry standards for potency, purity, quality and bioavailability. How Nature's Plus Creates the Highest Quality Herbal Supplements and Vitamins
Strict GMP Compliance
Standardized, Superior-Quality Herbal Ingredients - The effectiveness of Herbal Actives supplements and vitamins starts with using the highest quality, purest herbal extracts and active ingredients. With standardization, every Herbal Actives herbal formula not only provides the highest concentration of active botanical principles, but also maintains the herb's complete profile of balanced constituents, to maximize the synergistic benefits in every serving. You'll find this consistency in every herbal supplement and vitamin produced by Nature's Plus .
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The Herbal Actives line is manufactured under strict GMP compliance. GMP refers to "Good Manufacturing Practice" regulations established by the US Food and Drug Administration for pharmaceutical drug companies. The Nature's Plus manufacturing facilities are so exceptional that the FDA gives other manufacturers a guided tour of our facilities to show a "model manufacturing facility." Take a closer look at Herbal Actives' rich variety of botanical and herbal vitamins and supplements from Nature's Plus , the industry's gold standard bearer for quality, innovation and reliability. Place your order online with confidence. Your satisfaction is guaranteed!
About Nature's Plus
Nature's Plus has been considered the gold standard in Natural Vitamins and Nutritional Supplements for over 40 years.
In the early 1970s, when Gerald Kessler founded Nature's Plus, he had a clear vision of the kind of products he wanted to produce. Carefully studying the natural vitamin market, he observed that consumers were seeking energy and an enhanced quality of life from their vitamins. He knew that only a supplement made with superior ingredients and the highest standards of manufacturing could result in exceptional products with the energy-releasing results consumers demanded.
Over 1,200 Natural Vitamins and Nutritional Supplements Later
They continue to fine-tune their products and raise the bar for quality and performance in their industry. Today Nature's Plus products are unsurpassed in their ability to release natural energy and provide the ultimate feeling of well-being. That's why they call them the "Energy Supplements."
The Nature's Plus Quality Commitment
Nature's Plus has worked hard to earn the loyalty of millions of satisfied consumers and health food retailers worldwide with our emphasis on high quality at every stage - from manufacturing to on-time delivery to retailers:
Selection of the highest quality safe and natural ingredients
Over 1,200 natural vitamins and nutritional supplements to meet a wide variety of needs
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Innovative vitamins and supplements enhanced with special combinations of ingredients for maximum health and energy benefits
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