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Thorne Research - Meriva-SR Curcumin Phytosome 500 mg. - 120 Vegetarian Capsules

Curcumin Complexed with Phosphatidylcholine for Superior Bioavailability

Item #: 109624
MSRP: $39.60$39.60 Per Serving: $0.66
Serving Size: 2.00Capsule(s)
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Thorne Research - Meriva-SR Curcumin Phytosome 500 mg. - 120 Vegetarian Capsules

  • Code#:109624
  • Manufacturer:Thorne Research
  • Size/Form:120  Vegetarian Capsules
  • Packaged Ship Weight:0.35
  • Servings:60
  • Dosage Size:2  Capsule(s)
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Thorne Research Meriva-SR Curcumin Phytosome 500 mg. - 120 Vegetarian Capsules

Meriva-SR is a unique, patented, time-release curcumin product. People throughout Asia have benefited from the healthful effects of curcumin for centuries. Curcumin is the orange pigment in turmeric (the primary ingredient in curry), and is a potent antioxidant that offers numerous health benefits, including supporting joint health and cardiovascular function, and helping to maintain the body's normal inflammatory response.

  • to help maintain the body's normal inflammatory response
  • provides potent antioxidant and hepatoprotective activity
  • sustained-release formula allows for an optimal curcumin blood level over time
  • significantly increased bioavailability from phytosome preparation

Whether taken as a supplement or from food, curcumin is generally poorly absorbed into the bloodstream. In conjunction with Indena S.p.A., the worldwide experts in botanical extract technology, Thorne has uncovered the key to curcumin absorption – phytosome technology. Meriva curcumin phytosome is a unique curcumin extract that is significantly better absorbed than other curcumin extracts.

Phytosomes are plant extracts bound to phosphatidylcholine (PC), an essential component of human cells. Our bodies can make PC, but we can also get it from food or supplements. When taken orally, PC is very well absorbed. The scientists at Indena found a way to attach a curcumin extract to PC for superior absorption, resulting in Meriva. When you take Meriva your body absorbs the PC and the attached curcumin, resulting in more curcumin reaching the cells that can benefit from it. Meriva provides your patients with significantly more bioavailability than any curcumin extract or compound currently available. Phytosomes are created by a patented process that binds and herbal extract to phosphatidylcholine, a principal element of cell membranes. This unique phytosome complex easily crosses the gut barrier, unlike common herbal extracts, and results in significantly higher blood levels than standardized 95% curcumin extract.

Phytosome Technology:

  • Marked enhancement of bioavailability
  • Significantly greater clinical benefits
  • Assured delivery to the tissues
  • No compromise of nutrient safety
  • Unique time-release matrix

It is commonly known that when taken orally curcumin is poorly absorbed. Meriva is a highly absorbable curcumin extract that uses Indena's phytosome technology to significantly increase its absorption. Phytosomes are a precise linkage of a plant flavonoid molecule with a phospholipid molecule - in this case, phosphatidylcholine. A bond is formed between the two molecules to create a hybrid molecule, providing superior absorption and utilization of the attached botanical extract.

A 2007 study published in the journal, Cancer Chemotherapy and Pharmacology, demonstrated Meriva's superior bioavailability compared to ordinary curcumin. This animal study indicated a significantly greater plasma concentration time curve, with an area under the curve (AUC) five times higher for Meriva. Liver levels of curcumin were also higher with Meriva supplementation. A recent human study (not yet published) demonstrated 29-times greater bioavailability. In both studies, Meriva supplementation resulted in higher plasma concentrations of curcumin from a much smaller dose than with ordinary curcumin.

In a recent eight-month human trial, Meriva was shown to support a healthy inflammatory response. Individuals experienced improvements in clinical and biochemical end-points associated with joint health. One small unpublished, single-dose trial demonstrated 450 mg of Meriva (curcuminoids complexed with phosphatidylcholine) was absorbed as efficiently as 4 grams unbound Curcuma longa (95% curcumin), reflecting a significant increase in bioavailability for Meriva complex.

Several studies have illustrated curcumin's hepatoprotective effects, leading researchers to suggest its use in protecting the liver from exogenous insults from environmental toxins. Curcumin also has the capacity to increase both the flow and solubility of bile. Curcumin's hepatoprotective effects are due in part to direct free-radical scavenging; but curcumin also enhances the body's natural antioxidant system, which increases glutathione levels, thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.

Dr. Michael Lebowitz D.C. Recommends:
One of Dr. Michael Lebowitz's favorite more recent additions to the Thorne line, Meriva-SR is a patented time-released form of Curcumin. It has strong anti-inflammatory effects and is hepatoprotective. Dr. Michael Lebowitz has found many people with chronic spinal pain see the pain disappear while on Meriva when nothing else works.

Thorne Research's Mission
At Thorne Research, their mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

The Thorne Difference.
For more than 25 years, Thorne has relentlessly pursued the highest possible quality and bioavailability in dietary supplements. At Thorne, they actually manufacture products that they sell – a key difference that allows Thorne to control every aspect of the manufacturing process and ensure that every Thorne product is in pure, completely hypoallergenic form, and without the common additives, flowing agents, and binders used throughout the industry.

A few other companies have tried to do what Thorne does, and many others claim to have the same philosophy and quality, but nobody has been able to duplicate what Thorne's clients call "Thorne Quality." Thorne has changed the industry in many ways over the past two decades, and they continue to raise the bar and set new standards in product formulation, raw material purity, manufacturing, and quality control.

Thorne's Commitment to Purity
Practitioners have become accustomed to seeing the vague "We use only the purest ingredients" in the promotional materials of almost every dietary supplement company. Perhaps these companies truly believe that. Perhaps they don't know any better. Nevertheless, Thorne Research, for more than 25 years, has been the standard by which companies in the industry are judged for product purity. Practitioners rely on Thorne as the company they trust for their extremely allergic, chemically sensitive, and immune-compromised patients.

Purity Takes Extra Effort
For example, instead of purchasing prediluted vitamin D, as other companies do, Thorne performs its own dilution to avoid detrimental ingredients, such as the preservatives or lactose that are found in many commercially available dilutions. Why must vitamin D be diluted? Because in its pure form, it is too concentrated to safely blend into a vitamin product. Pure vitamin D is 40 MILLION International Units (IU) per gram. The RDA for adults is 600-800 IU per day. To ensure proper mixing, it must be made into a dilute powder that flows and does not lose potency. So, unlike companies that use prediluted vitamin D that contains unacceptable excipients and preservatives, at Thorne, pure pharmaceutical vitamin D is first blended with pure mixed tocopherol vitamin E, and the resultant stable vitamin D is then blended with hypoallergenic cellulose powder. The final powder is blended in a large tumble blender and subsequently analyzed. Not only is the final product stable; it is also hypoallergenic and can be mixed homogeneously and at a safe level with other powders. Just as with vitamin D, Thorne utilizes similar processes for other raw materials, such as vitamin K, leaving it to other companies to purchase commercially available raw materials filled with unacceptable ingredients and preservatives.

Ingredients You Don't Want
Magnesium Stearate: Good for speed-hungry encapsulating machines. Not necessarily good for you. Manufacturing encapsulated dietary supplements isn't easy. Pure powdered ingredients are difficult to mix because they are either extremely dry, sticky with botanical oils, or attract unwanted moisture. So most manufacturers add magnesium stearate and other agents such as lactose and dextrose to make the powder flow quickly and easily through their high-volume machines. Problem is, these additives may compromise the bioavailability of the nutrients in the supplement, and might cause allergenic problems. At Thorne, they take a different approach.

Thorne will never utilize large fatty acid excipients in its manufacturing processes – ingredients such as magnesium stearate or stearic acid. These excipients are utilized as flowing agents to ensure that maximum productivity is obtained from capsuling and tableting machines. There are documented detrimental effects directly attributed to long chain fatty acids utilized as manufacturing flowing agents. Every qualified pharmaceutical compounder recognizes that large fatty acids, such as magnesium stearate, can interfere with product dissolution and influence absorption. Virtually all companies, because of the economic impact, ignore this data. As with most industries, the bottom line dictates the level of quality. The dietary supplement industry has one exception: Thorne Research, the company that does not compromise. Nevertheless, if a company cannot manufacture products without using detrimental excipients, they should not allude to being either "hypoallergenic" or "pure."

The Bottom Line?
Thorne is the only hypoallergenic dietary supplement manufacturer with the highest degree of purity that you – and your most severely allergic, chemically sensitive, and immune-compromised patients – can truly trust.

Quality Ingredients: A Higher Standard
At Thorne, they are committed to setting a higher standard of quality when it comes to ingredients. To produce their truly hypoallergenic encapsulated supplements, Thorne uses only the purest and finest ingredients available.

Every manufacturer has two basic options when purchasing raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. This fundamental dilemma translates to these very typical questions: "Do I purchase pure vitamin C or vitamin C with additives?" "Do I purchase pure B vitamins or coated B vitamins for taste masking?" "Do I purchase pure enzymes such as pancreatin, pepsin, and bromelain or enzymes diluted with lactose?"

There are few commercial sources for vitamins B12, D, K, or biotin that are not diluted with substances such as lactose, cornstarch, and preservatives such as BHT. That's why Thorne developed methods that allow them to use pure, undiluted sources of these nutrients – and many others. It's just one more example that when it comes to quality, what everyone else accepts as an industry standard isn't good enough. While some companies say they are raising their standards....at Thorne they set them.

Suggested Use

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Take 1-2 capsules two times daily or as recommended by your health-care practitioner.

Store tightly sealed in a cool, dry place.

ALLERGY WARNINGS
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Meriva-SR contains curcumin phytosome - a plant extract complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Meriva-SR.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.


Thorne Research Meriva-SR Curcumin Phytosome - 120 Vegetarian Capsules
Supplement Facts
Serving Size: Two Capsules
Servings Per Container: 60
Amount Per Serving %DV*
Curcumin Phytosome+ (Curcuma longa extract (root) / Phosphatidylcholine complex) 500 mg *
*Daily Value Not Established.
**Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
 

Other Ingredients: High and low viscosity hydroxypropyl methyl-cellulose and CalciumCitrateLaurate, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide, Microcrystalline Cellulose

Contains ingredient derived from soy (phytosome).

Hypoallergenic.

+Curcumin Phytosome (Meriva) complexed with Time-Sorb, a time-release matrix. This product uses Indena S.p.A's curcumin phytosome (Meriva). Meriva is a registered trademark of Indena S.p.A.

Average Rating

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Recommendation

83%5 out of 6 reviewers would recommend this product to a friend.
Bought this product? write a review

By John (Destrehan , LA )

-- Remains to be seen. Have just begun using product.

I RECOMMEND THIS PRODUCT!
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By Margaret (Palmetto , FL )

Totally replaced my meloxicam with this curcumin. It definately helps my joint pain, almost as well as the prescription drug. I take it religiously twice a day.

I RECOMMEND THIS PRODUCT!
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By Yvette (Kissimmee , FL )

I've been taking 2 Meriva 500 capsules daily for about 9 months. I'm a 53 yr old female. I had gone to a clinic with terrible shoulder a/c joint pain

I RECOMMEND THIS PRODUCT!
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By Patricia J (San Diego , CA )

the reason that I gave the Thorne curcumin 3 sars is because it's too early to tell. My doctor recommended it over any other curcumin because there has been research on it giving it a favorable rating over all other curcumins. You can verify this be Googling Thorne Meriva curcumin.

I RECOMMEND THIS PRODUCT!
Was this review helpful?YesNoThank you for your response.

Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

Manufacturer Info

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P.O. Box 25
Dover, ID,
Phone: 800-228-1966 Fax: 800-747-1950 Visit website

About Thorne Research

At Thorne Research, our mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

*The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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