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Thorne Research - Meriva-500 Curcumin Phytosome 1000 mg. - 120 Vegetarian Capsules

Curcumin Complexed with Phosphatidylcholine for Superior Bioavailability

Item #: 109574
MSRP: $51.50$51.50 Per Serving: $0.86
Serving Size: 2.00Capsule(s)
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Thorne Research - Meriva-500 Curcumin Phytosome 1000 mg. - 120 Vegetarian Capsules

  • Code#:109574
  • Manufacturer:Thorne Research
  • Size/Form:120  Vegetarian Capsules
  • Packaged Ship Weight:0.40
  • Servings:60
  • Dosage Size:2  Capsule(s)
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Thorne Research Meriva-500 Curcumin Phytosome - 120 Vegetarian Capsules

Meriva-500 is a unique, patented curcumin product. People throughout Asia have benefited from the healthful effects of curcumin for centuries. Curcumin is the orange pigment in turmeric (the primary ingredient in curry), and is a potent antioxidant that offers numerous health benefits, including supporting joint health and hepatic, GI, and cardiovascular function, by helping to maintain the body's normal inflammatory response.

  • for maintenance of the body's normal inflammatory response
  • provides potent antioxidant and hepatoprotective activity
  • significantly increased bioavailability from phytosome preparation

Whether taken as a supplement or from food, curcumin is generally poorly absorbed into the bloodstream. In conjunction with Indena S.p.A., the worldwide experts in botanical extract technology, we have uncovered the key to curcumin absorption – phytosome technology. Meriva curcumin phytosome is a unique curcumin extract that is significantly better absorbed than other curcumin extracts.

Phytosomes are plant extracts bound to phosphatidylcholine (PC), an essential component of human cells. Our bodies can make PC, but we can also get it from food or supplements. When taken orally, PC is very well absorbed. The scientists at Indena found a way to attach a curcumin extract to PC for superior absorption, resulting in Meriva. When you take Meriva your body absorbs the PC and the attached curcumin, resulting in more curcumin reaching the cells that can benefit from it.

Meriva provides your patients with significantly more bioavailability than any curcumin extract or compound currently available. Phytosomes are created by a patented process that binds and herbal extract to phosphatidylcholine, a principal element of cell membranes. This unique phytosome complex easily crosses the gut barrier, unlike common herbal extracts, and results in significantly higher blood levels than standardized 95% curcumin extract.

Phytosome Technology:

  • Marked enhancement of bioavailability
  • Significantly greater clinical benefits
  • Assured delivery to the tissues
  • No compromise of nutrient safety

It is commonly known that when taken orally curcumin is poorly absorbed. Meriva is a highly absorbable curcumin extract that uses Indena's phytosome technology to significantly increase its absorption. Phytosomes are a precise linkage of a plant flavonoid molecule with a phospholipid molecule - in this case, phosphatidylcholine. A bond is formed between the two molecules to create a hybrid molecule, providing superior absorption and utilization of the attached botanical extract.

A 2007 single-dose pharmacokinetic animal study demonstrated Meriva's superior bioavailability, compared to ordinary curcumin. The results demonstrated a >20-fold increase in absorption of curcumin from Meriva versus a standard curcumin preparation. In addition, a 2010 three-month clinical trial demonstrated 1,000 mg of Meriva-SR per day helped maintain healthy C-reactive protein levels and promoted healthy joint comfort and mobility. Furthermore, a 2010 randomized, single-blind, crossover human study revealed total curcuminoid bioavailability, as evaluated by the plasma area under the curve (AUC), to be 29-fold higher for Meriva than for the conventional standardized curcumin extract.

Several studies have illustrated curcumin's hepatoprotective effects, leading researchers to suggest its use in protecting the liver from exogenous insults from environmental toxins. Curcumin also has the capacity to increase both the flow and solubility of bile. Curcumin's hepatoprotective effects are due in part to direct free-radical scavenging; but curcumin also enhances the body's natural antioxidant system, which increases glutathione levels, thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.

Thorne Research's Mission
At Thorne Research, their mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

The Thorne Difference.
For more than 25 years, Thorne has relentlessly pursued the highest possible quality and bioavailability in dietary supplements. At Thorne, they actually manufacture products that they sell – a key difference that allows Thorne to control every aspect of the manufacturing process and ensure that every Thorne product is in pure, completely hypoallergenic form, and without the common additives, flowing agents, and binders used throughout the industry.

A few other companies have tried to do what Thorne does, and many others claim to have the same philosophy and quality, but nobody has been able to duplicate what Thorne's clients call "Thorne Quality." Thorne has changed the industry in many ways over the past two decades, and they continue to raise the bar and set new standards in product formulation, raw material purity, manufacturing, and quality control.

Thorne's Commitment to Purity
Practitioners have become accustomed to seeing the vague "We use only the purest ingredients" in the promotional materials of almost every dietary supplement company. Perhaps these companies truly believe that. Perhaps they don't know any better. Nevertheless, Thorne Research, for more than 25 years, has been the standard by which companies in the industry are judged for product purity. Practitioners rely on Thorne as the company they trust for their extremely allergic, chemically sensitive, and immune-compromised patients.

Purity Takes Extra Effort
For example, instead of purchasing prediluted vitamin D, as other companies do, Thorne performs its own dilution to avoid detrimental ingredients, such as the preservatives or lactose that are found in many commercially available dilutions. Why must vitamin D be diluted? Because in its pure form, it is too concentrated to safely blend into a vitamin product. Pure vitamin D is 40 MILLION International Units (IU) per gram. The RDA for adults is 600-800 IU per day. To ensure proper mixing, it must be made into a dilute powder that flows and does not lose potency. So, unlike companies that use prediluted vitamin D that contains unacceptable excipients and preservatives, at Thorne, pure pharmaceutical vitamin D is first blended with pure mixed tocopherol vitamin E, and the resultant stable vitamin D is then blended with hypoallergenic cellulose powder. The final powder is blended in a large tumble blender and subsequently analyzed. Not only is the final product stable; it is also hypoallergenic and can be mixed homogeneously and at a safe level with other powders. Just as with vitamin D, Thorne utilizes similar processes for other raw materials, such as vitamin K, leaving it to other companies to purchase commercially available raw materials filled with unacceptable ingredients and preservatives.

Ingredients You Don't Want
Magnesium Stearate: Good for speed-hungry encapsulating machines. Not necessarily good for you. Manufacturing encapsulated dietary supplements isn't easy. Pure powdered ingredients are difficult to mix because they are either extremely dry, sticky with botanical oils, or attract unwanted moisture. So most manufacturers add magnesium stearate and other agents such as lactose and dextrose to make the powder flow quickly and easily through their high-volume machines. Problem is, these additives may compromise the bioavailability of the nutrients in the supplement, and might cause allergenic problems. At Thorne, they take a different approach.

Thorne will never utilize large fatty acid excipients in its manufacturing processes – ingredients such as magnesium stearate or stearic acid. These excipients are utilized as flowing agents to ensure that maximum productivity is obtained from capsuling and tableting machines. There are documented detrimental effects directly attributed to long chain fatty acids utilized as manufacturing flowing agents. Every qualified pharmaceutical compounder recognizes that large fatty acids, such as magnesium stearate, can interfere with product dissolution and influence absorption. Virtually all companies, because of the economic impact, ignore this data. As with most industries, the bottom line dictates the level of quality. The dietary supplement industry has one exception: Thorne Research, the company that does not compromise. Nevertheless, if a company cannot manufacture products without using detrimental excipients, they should not allude to being either "hypoallergenic" or "pure."

The Bottom Line?
Thorne is the only hypoallergenic dietary supplement manufacturer with the highest degree of purity that you – and your most severely allergic, chemically sensitive, and immune-compromised patients – can truly trust.

Quality Ingredients: A Higher Standard
At Thorne, they are committed to setting a higher standard of quality when it comes to ingredients. To produce their truly hypoallergenic encapsulated supplements, Thorne uses only the purest and finest ingredients available.

Every manufacturer has two basic options when purchasing raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. This fundamental dilemma translates to these very typical questions: "Do I purchase pure vitamin C or vitamin C with additives?" "Do I purchase pure B vitamins or coated B vitamins for taste masking?" "Do I purchase pure enzymes such as pancreatin, pepsin, and bromelain or enzymes diluted with lactose?"

There are few commercial sources for vitamins B12, D, K, or biotin that are not diluted with substances such as lactose, cornstarch, and preservatives such as BHT. That's why Thorne developed methods that allow them to use pure, undiluted sources of these nutrients – and many others. It's just one more example that when it comes to quality, what everyone else accepts as an industry standard isn't good enough. While some companies say they are raising their standards....at Thorne they set them.

Suggested Use

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Take 1-2 capsules two times daily or as recommended by your health-care practitioner.

Store tightly sealed in a cool, dry place.

ALLERGY WARNINGS
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

Meriva-500 contains curcumin phytosome – a plant extract complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Meriva-500.

PURITY
This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS
Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.


Thorne Research Meriva-500 Curcumin Phytosome - 120 Vegetarian Capsules
Supplement Facts
Serving Size: Two Capsules
Servings Per Container: 60
Amount Per Serving %DV*
Curcumin Phytosome (Curcuma longa extract (root) / Phosphatidylcholine complex) 1000 mg *
*Daily Value Not Established.
**Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
 

Other Ingredients: Hypromellose (derived from cellulose) capsule, Leucine, CalciumCitrateLaurate, Silicon Dioxide, Microcrystalline Cellulose

Hypoallergenic.

Average Rating

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Recommendation

100%1 out of 1 reviewers would recommend this product to a friend.
Bought this product? write a review

By Barbara (South Lyon , MI )

I have found almost immediately that my general acheness upon getting up in the morning has gone away and my joints feel more "oiled". Would recommed it to everyone.

I RECOMMEND THIS PRODUCT!
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Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

Manufacturer Info

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P.O. Box 25
Dover, ID,
Phone: 800-228-1966 Fax: 800-747-1950 Visit website

About Thorne Research

At Thorne Research, our mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

*The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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