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Thorne Research - 5-MTHF 1 mg. - 60 Vegetarian Capsules

The Most Biologically Active Form of Folic Acid

Item #: 109371
$19.95 Per Serving: $0.33
Serving Size: 1 Capsule(s)
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Thorne Research - 5-MTHF 1 mg. - 60 Vegetarian Capsules

  • Code#:109371
  • Manufacturer:Thorne Research
  • Size/Form:60  Vegetarian Capsules
  • Packaged Ship Weight:0.25
  • Servings:60
  • Dosage Size:1  Capsule(s)
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Thorne Research 5-MTHF 1 mg. - 60 Vegetarian Capsules

Folic acid must be converted to its active forms to be used by the body. This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.

Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy. The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant. Supplementation with the more active form may be preferable.

In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine. Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.

It is important for women of childbearing age to get enough folic acid - not just those who are planning to become pregnant. Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day - especially before conception and during early pregnancy.

  • a breakthrough in folate supplementation
  • the most bioavailable, active form of folate
  • an excellent source of folate for pregnant women
  • supports optimal cardiovascular and neurological function
  • made without flowing agents that can inhibit bioavailability

Dr. Michael Lebowitz D.C. Recommends:
Many people have difficulty or an inability to convert inactive folic acid to its bioactive form. 5-MTHF is the most bioactive form. It acts as a methyl donor and is involved in neurotransmitter synthesis and nitric oxide production. From an AK standpoint, Dr. Michael Lebowitz D.C. tests this as well as Folacal and Folic Acid Liquid and lets his test results decide which supplement to prescribe.

Thorne Research's Mission
At Thorne Research, their mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

The Thorne Difference.
For more than 25 years, Thorne has relentlessly pursued the highest possible quality and bioavailability in dietary supplements. At Thorne, they actually manufacture products that they sell – a key difference that allows Thorne to control every aspect of the manufacturing process and ensure that every Thorne product is in pure, completely hypoallergenic form, and without the common additives, flowing agents, and binders used throughout the industry.

A few other companies have tried to do what Thorne does, and many others claim to have the same philosophy and quality, but nobody has been able to duplicate what Thorne's clients call "Thorne Quality." Thorne has changed the industry in many ways over the past two decades, and they continue to raise the bar and set new standards in product formulation, raw material purity, manufacturing, and quality control.

Thorne's Commitment to Purity
Practitioners have become accustomed to seeing the vague "We use only the purest ingredients" in the promotional materials of almost every dietary supplement company. Perhaps these companies truly believe that. Perhaps they don't know any better. Nevertheless, Thorne Research, for more than 25 years, has been the standard by which companies in the industry are judged for product purity. Practitioners rely on Thorne as the company they trust for their extremely allergic, chemically sensitive, and immune-compromised patients.

Purity Takes Extra Effort
For example, instead of purchasing prediluted vitamin D, as other companies do, Thorne performs its own dilution to avoid detrimental ingredients, such as the preservatives or lactose that are found in many commercially available dilutions. Why must vitamin D be diluted? Because in its pure form, it is too concentrated to safely blend into a vitamin product. Pure vitamin D is 40 MILLION International Units (IU) per gram. The RDA for adults is 600-800 IU per day. To ensure proper mixing, it must be made into a dilute powder that flows and does not lose potency. So, unlike companies that use prediluted vitamin D that contains unacceptable excipients and preservatives, at Thorne, pure pharmaceutical vitamin D is first blended with pure mixed tocopherol vitamin E, and the resultant stable vitamin D is then blended with hypoallergenic cellulose powder. The final powder is blended in a large tumble blender and subsequently analyzed. Not only is the final product stable; it is also hypoallergenic and can be mixed homogeneously and at a safe level with other powders. Just as with vitamin D, Thorne utilizes similar processes for other raw materials, such as vitamin K, leaving it to other companies to purchase commercially available raw materials filled with unacceptable ingredients and preservatives.

Ingredients You Don't Want
Magnesium Stearate: Good for speed-hungry encapsulating machines. Not necessarily good for you. Manufacturing encapsulated dietary supplements isn't easy. Pure powdered ingredients are difficult to mix because they are either extremely dry, sticky with botanical oils, or attract unwanted moisture. So most manufacturers add magnesium stearate and other agents such as lactose and dextrose to make the powder flow quickly and easily through their high-volume machines. Problem is, these additives may compromise the bioavailability of the nutrients in the supplement, and might cause allergenic problems. At Thorne, they take a different approach.

Thorne will never utilize large fatty acid excipients in its manufacturing processes – ingredients such as magnesium stearate or stearic acid. These excipients are utilized as flowing agents to ensure that maximum productivity is obtained from capsuling and tableting machines. There are documented detrimental effects directly attributed to long chain fatty acids utilized as manufacturing flowing agents. Every qualified pharmaceutical compounder recognizes that large fatty acids, such as magnesium stearate, can interfere with product dissolution and influence absorption. Virtually all companies, because of the economic impact, ignore this data. As with most industries, the bottom line dictates the level of quality. The dietary supplement industry has one exception: Thorne Research, the company that does not compromise. Nevertheless, if a company cannot manufacture products without using detrimental excipients, they should not allude to being either "hypoallergenic" or "pure."

The Bottom Line?
Thorne is the only hypoallergenic dietary supplement manufacturer with the highest degree of purity that you – and your most severely allergic, chemically sensitive, and immune-compromised patients – can truly trust.

Quality Ingredients: A Higher Standard
At Thorne, they are committed to setting a higher standard of quality when it comes to ingredients. To produce their truly hypoallergenic encapsulated supplements, Thorne uses only the purest and finest ingredients available.

Every manufacturer has two basic options when purchasing raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. This fundamental dilemma translates to these very typical questions: "Do I purchase pure vitamin C or vitamin C with additives?" "Do I purchase pure B vitamins or coated B vitamins for taste masking?" "Do I purchase pure enzymes such as pancreatin, pepsin, and bromelain or enzymes diluted with lactose?"

There are few commercial sources for vitamins B12, D, K, or biotin that are not diluted with substances such as lactose, cornstarch, and preservatives such as BHT. That's why Thorne developed methods that allow them to use pure, undiluted sources of these nutrients – and many others. It's just one more example that when it comes to quality, what everyone else accepts as an industry standard isn't good enough. While some companies say they are raising their standards....at Thorne they set them.

Suggested Use

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Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

EXCIPIENT FREE
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS/CONTRAINDICATIONS
5-methyl-tetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.


Thorne Research 5-MTHF 1 mg. - 60 Vegetarian Capsules
Supplement Facts
Serving Size: One Capsule
Servings Per Container: 60
Amount Per Serving %DV*
Folate (as L-5-Methyltetrahydrofolate+) 1 mg 250%
+Daily Value Not Established.
**Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
 

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide

Hypoallergenic.

+This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolate (Extrafolate-S)

Average Rating

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Recommendation

100%5 out of 5 reviewers would recommend this product to a friend.
Bought this product? write a review

By Sarah (Park Rapids , MN )

One of the only 5-MTHF in the L strand that works for my Methylation defect. My body doesn't absorb other forms.

I RECOMMEND THIS PRODUCT!
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By Gale (Fleming Island , FL )

Very good product. I like Thorne Research

I RECOMMEND THIS PRODUCT!
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By Lois (Iowa City , IA )

I am getting great results with the 5-MTHF. I feel much less anxiety. I am glad i was referred to Lucky vitamin. The price is competitive and reasonable and it shipped right away. Thank you.

I RECOMMEND THIS PRODUCT!
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By GAIL (Marietta , GA )

Best folic acid product, per my internist. Will continue to take.

I RECOMMEND THIS PRODUCT!
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By Kyra D (Bethlehem , PA )

Hard to say if this supplement is "working" or not yet, but I did extensive research on folate/folic acid, and chose this instead as the best option (Folic acid must be converted to its active forms to be used by the body. 5-MTHF is the active form). I'm taking this to prepare my body for possible pregnancy. Pill size is small, no side effects.

I RECOMMEND THIS PRODUCT!
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Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

Manufacturer Info

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P.O. Box 25
Dover, ID,
Phone: 800-228-1966 Fax: 800-747-1950 Visit website

About Thorne Research

At Thorne Research, our mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.

*The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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