Douglas Laboratories Alpha-Lipoic Acid - 60 Tablets
Douglas Laboratories Alpha-Lipoic Acid contain 100 mg of pure alpha-lipoic acid. Alpha-lipoic acid is a non-vitamin coenzyme that carries out important metabolic and antioxidant functions in the body. Alpha-lipoic acid is a nutritional coenzyme that is involved in energy metabolism of proteins, carbohydrates and fats, has physiological functions in blood glucose disposal, and is able to scavenge a number of free radicals.
Alpha-lipoic acid is a fat- and water-soluble, sulfurcontaining coenzyme. It functions in the body much like a B-vitamin, since it is involved in energy production. As part of several multi-enzyme complexes located in the mitochondria, alpha-lipoic acid is essential for metabolizing carbohydrates, proteins, and fats, and for the conversion of their energy into ATP. Two of these enzyme complexes, PDH (pyruvate dehydrogenase) and alpha-KGDH (alpha-ketoglutarate dehydrogenase) are part of the citric acid cycle (Krebs cycle), and as such assume a central role for general energy production. Another lipoic acid containing enzyme complex, BCKADH (branched-chain keto-acid dehydrogenase), is involved in deriving energy from the branched chain amino acids, leucine, isoleucine, and valine. A related metabolic function of alpha-lipoic acid is its role in blood glucose disposal. This important coenzyme appears to be necessary for the normal transport of blood glucose into the cell. This may be explained by its functions in the glucosemetabolizing enzymes, PDH and alpha-KGDH, but some researchers suspect a more direct role in cellular glucose uptake at the cell membrane. As early as 1959, alpha-lipoic acid was suggested to be an antioxidant, since it could extend the actions of vitamin C in guinea pigs, and those of vitamin E in rats. It is only recently, however, that the specific actions of alpha-lipoic acid in free radical quenching, metal chelation, and antioxidant regeneration have been investigated.
Body cells and tissues are threatened continuously by damage caused by toxic free radicals and reactive oxygen species (e.g., peroxides) which are produced during normal oxygen metabolism, and by toxic agents in the environment. Free radicals, once formed, are capable of disrupting metabolic activity and cell structure. When this occurs, additional free radicals are produced which, in turn, can result in more extensive damage to cells and tissues. The uncontrolled production of free radicals is thought to be a major contributing factor to many degenerative diseases.
Alpha-lipoic acid is unique among biological antioxidants, because it is soluble in both water and lipids. This allows it to neutralize free radicals just about everywhere in the body, inside and outside the cells. Due to its unique sulfur-containing structure, alpha-lipoic acid can scavenge several types of free radicals, such as the highly reactive hydroxyl, and singlet oxygen free radicals. It is also capable of suppressing the generation of free radicals in the first place, since alpha-lipoic acid chelates transition metals, such as iron and copper. Because alphalipoic acid is involved in so many different antioxidant functions in virtually all body tissues, it has been called the universal antioxidant. Besides being a universal free radical scavenger, alpha-lipoic acid can also recharge other antioxidant systems throughout the body. As mentioned earlier, it can extend the activity of vitamins C and E. In addition, alpha-lipoic acid can also regenerate glutathione.
Alpha-lipoic acid may be a beneficial dietary supplement for those concerned about a more complete antioxidant defense system and maintaining proper glucose metabolism. Dietary and supplementary alpha-lipoic acid is efficiently absorbed, transported to the tissues, and readily taken up by the cells.
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About Douglas Laboratories
Back in 1955, Sam Lioon, founded Douglas Laboratories on a simple promise: provide the highest quality nutritional supplements available with the highest level of personal service—anywhere. And with that promise began a legacy of leadership—and a never-ending quest to exceed their customers’ expectations to Raise the Standard for Nutrition and Wellness.
Today that legacy lives on as Douglas Laboratories proudly joins the Atrium Innovations group of companies. Atrium Innovations is an international company and global leader in the development, manufacturing, and marketing of dietary supplements, specialty fine chemicals, and active cosmetic ingredients.
Douglas Laboratories is supported by more than 300 Douglas Laboratories employees all dedicated to keeping the promise Sam made 50 years ago. Raising the Standard is more than a slogan—it’s a promise. As they enter their second half-century, Douglas Laboratories will continue to keep their promise to Raise the Standard with a custom approach to ytheir patients’ nutrition and wellness. With custom formulations ytheir patients can’t find anywhere else. Custom labels. Custom daily packs. And the industry’s largest and most innovative product line. And they’ll back up their promise with the kind of stringent criteria many other companies overlook, such as:
(cGMPs) current good manufacturing practices.
ISO 9001 Certification and ISO 17025 Accreditation of their laboratories.
The industry’s first fully electronic, bar code driven, paperless manufacturing system to pass the FDA’s rigorous audit. Their exclusive Veri-Match labeling system, ensures verification prior to production and release of ytheir products.
(SOPs) standard operating procedures.
VCP (Vendor Certification Program) ensures raw material safety and quality.
Experienced, on-staff Ph.D’s, utilizing three full-service laboratories, outfitted with the latest analytical equipment.
State-of-the-art manufacturing, including ultra high-speed encapsulating machines, capable of producing over 35 million capsules and tablets daily!
Full compliance with the Public Health Security and Bioterrorism Preparedness and Response Act of 2002, assuring safety and uninterrupted flow of all raw materials.
Douglas Laboratories continues to lead the way with clinical trials designed to validate the efficacy of their products. Their world-renowned Ultra-Preventive X (Ten) was rated the #1 multivitamin in the professional healthcare market, and their Vita-Big-Kids was rated the #1 children’s multivitamin overall by the independent Comparative Guide to Nutritional Supplements. Their commitment to help support patient outcomes is ongoing; look for their new in-office patient education posters, easy online ordering from their website and more innovative ideas designed to help ytheir practice grow in the days ahead.
But most of all, they’re proud of the many long-standing relationships they’ve enjoyed with so many customers over the years, and the many great friendships they’ve made along the way. It’s not an exaggeration to say that they truly enjoy what they do, enjoy coming to work each and every day.