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Biotics Research - E-200 Hg Gamma - 120 Capsules

Item #: 107410
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    Biotics Research - E-200 Hg Gamma - 120 Capsules

    • Code#:107410
    • Manufacturer:Biotics Research
    • Size/Form:120  Capsules
    • Packaged Ship Weight:0.35
    • Servings:120
    • Dosage Size:1  Capsule(s)

    Biotics Research E-200 Hg Gamma - 120 Capsules

    Biotics Research E-200 Hg Gamma supplies 200 mg of d-Gamma tocopherol (y-tocopherol) with other mixed tocopherol isomers. Y-tocopherol, and its primary metabolite y-CEHC, have been shown to lower prostglandin E2 (PGE2) via the inhibition of COX-2. A study illustrated y-tocopherol's effects, showing a significant lowering of PGE2, along with a reduction of lipid peroxidation and LDH activity at the site of inflammation.

    Gamma Tocopherol (g-Tocopherol) - The unique biological and chemical properties of the tocopherols have been correlated to their important roles in the intracellular defense against radical-mediated damage. It has been suggested that in response to a cellular inflammatory state an increase in intracellular  g-tocopherol may be indicative of the role it serves, as a unique component in minimizing cellular damage resulting from the production of endogenous nitrous oxide (NO). Studies have speculated that the “paradoxical increase in cellular tocopherol associated with the induction of NO synthesis may indicate either enhanced cellular transport/decreased export for tocopherols or recruitment of free tocopherol from tocopherol storage molecules.”

    Additionally, increased consumption of  g-tocopherol has been associated with a reduced relevance of prostate complications.  Unlike a-tocopherol, g-tocopherol has been shown to exhibit anti-inflammatory activity. Both g-tocopherol, and its primary metabolite 2,7,8-trimethyl-2-(b-carboxyethyl) -6-hydroxychroman (g-CEHC), were shown to inhibit the synthesis of prostaglandin E2 (PGE2) via inhibition of its catalyst cycloxygenase-2 (COX2), providing evidence of  g-tocopherol’s anti-inflammatory properties.

    A subsequent study illustrated  g-tocopherol’s effects on PGE2. A significant lowering of PGE2, along with reduced lipid peroxidation and LDH activity was observed at the site of inflammation, as compared to a-tocopherol. The method of activation of tocopherols on COX-2 has been demonstrated to be posttranscriptionally, which is different from the activity of quercetin, shown to affect both transcription and activity of COX-2.  It is thus feasible to assume a complementary mechanism of these actions.



    Quality Control - What Sets Biotics Apart

    The Biotics Research way!


    At Biotics Research Corporation, we manufacture our own branded products on site, in our own state of the art facilities, allowing for complete control of the entire manufacturing process. In our on-site laboratories, the highly skilled members of our Quality Control Unit, utilize modern, sophisticated technologies and validated analytical methods to test incoming raw materials, monitor manufacturing processes, perform in-process testing, and test all finished products prior to their release for shipment. In fact, many aspects of our cGMPs (current Good Manufacturing Practices) exceed the new, recently enacted FDA guidelines for dietary supplements in order to ensure the safety and effectiveness of our products.
    The Quality Control Unit (QCU) has the authority to approve and/or reject all specifications and procedures associated with the production and release of all raw materials, packaging materials and finished products, including test methods and results, instrument calibrations, and processing records. The QCU conducts all internal audits, and validates and audits all raw material and packaging suppliers and service vendors as well.

    All incoming raw materials are subject to appropriate testing prior to their release for production. Tests conducted include identity, potency, biological activity, microbiological, including bacteria, yeast and mold (including aflatoxins) and heavy metals (arsenic, cadmium, lead & mercury). Retained samples are maintained of all raw materials and finished products for future testing requirements (raw material stability and finished product expiration date verification).

    All bulk finished products (tablets & capsules) are inspected and subjected to metal detection prior to being sampled by QC. They are then subject to appropriate disintegration and/or dissolution testing, and potency testing prior to being released to packaging. All liquid and powder products are tested for potency prior to packaging as well. Finally, microbiological testing is performed on all finished products and document reconciliation is completed prior to being released for shipment.

    All testing is performed by our trained QC personnel using state of the art laboratory instrumentation including High Pressure Liquid Chromatography (HPLC), ICP, Atomic Absorption Spectrophotometry (AA), gel electrophoresis, FT-IR, Ultra Violet spectrophotometry, Thin Layer chromatography and Gas Chromatography-Mass Spectrometry (GC-MS).

    Unlike many companies that are struggling to meet the new GMP requirements established by the FDA, companies that are being regulated into implementing quality programs, extensive Quality Control has always been part of the corporate fabric of Biotics Research Corporation.

    From day one, the mantra of Biotics Research Corporationhas been "Innovation and Quality." Our goals remain unchanged - utilize innovative ideas and carefully researched concepts with advanced techniques to develop products of superior quality and effectiveness - bringing you "The Best of Science and Nature".

    Suggested Use

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    One (1) softgel capsule each day as a dietary supplement or as otherwise recommended by your healthcare professional.


    Biotics Research - E-200 Hg Gamma - 120 Capsules
    Supplement Facts
    Serving Size: 1 Softgel Capsule
    Servings Per Container: 120
    Amount Per Serving %DV*
    Vitamin E (as d-Alpha tocopherol) 200 IU 667%
    d-Gamma tocopherol 200mg *
    Other tocopherols (d-Delta, d-Beta tocopherol) 78mg *
    Tocotrienols 2mg
    *Daily Value Not Established.
    †Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
     
    Other Ingredients: Soft capsule shell (gelatin, water and glycerin) and soybean oil.
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    Manufacturer Info

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    6801 BioticsResearch Dr.
    Rosenberg, TX,
    Phone: 800-231-5777 Fax: 281-344-0725 Visit website

    About Biotics Research

    Biotics Research Corporation has been a leading manufacturer of specially designed nutritional products for over thirty years. Our mission remains constant: to be the benchmark of excellence in nutritional science, technology and service, providing the clinician with reliable, innovative products of superior quality as well as the highest level of customer service.

    *The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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