Take 2-4 capsules daily as directed by your health care professional. Dr. Perlmutter recommends if you take this product you also take a multi-vitamin.

N-Acetyl-L-Cysteine (NAC) dramatically increases the body’s production of glutathione, one of the brain’s most important antioxidants. NAC itself is a potent antioxidant shown to reduce formation of nitric oxide, a free radical implicated for a causative role in Parkinson’s disease, Alzheimer’s disease, and other neurodegenerative disorders.(1)

* Phosphatidylserine produces marked memory and learning improvements in demented patients, according to research conducted at Stanford University.(2) Like acetyl-L-carnitine and coenzyme Q-10, phosphatidylserine plays an important role in neuronal energy production and chemical communication.

* Acetyl-L-Carnitine, like coenzyme Q-10, enhances neuronal energy pro-duction by transporting fuel sources into the mitochondria – the energy producing machinery of the neuron. This particularly benefits damaged brain neurons, which are characterized by decreased energy producing ability. In addition, acetyl-L-carnitine acts as an effective antioxidant and been demon-strated to protect laboratory animals from developing parkinsonism when they are exposed to chemicals known to induce the condition.(3) A report in a recent issue of Neurology found that acetyl-L-carnitine profoundly reduces the rate of progression of Alzheimer’s disease in younger patients.(4)

* Alpha Lipoic Acid provides powerful antioxidant action and regenerates other important brain antioxidants including vitamins E, C, and glutathione. Unlike other antioxidants, alpha lipoic acid is both fat- and water-soluble, greatly enhancing its ability to be absorbed from the gut and penetrate into the brain.(5)

* Coenzyme Q-10 measurably increases the efficiency of cellular energy production, as demonstrated in studies performed at the Massachusetts General Hospital.(6) In addition, it serves as a potent brain antioxidant. These effects explain why major institutions worldwide are vigorously evaluating coenzyme Q10 as a therapeutic aid in brain disorders.(7)

* Gingko biloba, one of the most extensively studied nutritional supplements for neurodegenerative conditions, directly improves brain metabolism, increases brain blood flow, and provides antioxidant action. In a placebo-controlled, double-blind randomized trial published in the Journal of the American Medical Association, Gingko biloba not only stabilized Alzheimer’s disease; many subjects demonstrated an actual improvement noted in various standardized psychological tests.(8)

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