Best Curcumin C3 Complex w/BioPerine® (1000mg) 120T

Best Curcumin C3 Complex® with Bioperine® tablets and Best Curcumin w/Bioperine® capsules contain a potent standardized extract of Curcuma longa root, commonly known as turmeric. Turmeric is the yellow spice that gives flavor to curried dishes. The herb has been employed in the Ayurvedic healing tradition for centuries as a folk remedy. The active ingredients in Curcuma longa are a group of plant substances called curcuminoids, a class of compounds that have demonstrated potent antioxidant properties in scientific studies. Curcuminoids may benefit the joints, brain, heart and the circulatory system by helping to neutralize free-radicals. Curcuminoids are responsible for turmeric’s distinctive yellow color. Although the term “curcumin” is used as a name for curcuminoids, “pure” curcumin is just one of the naturally occurring curcuminoids.

Curcumin C3 Complex supplies 95% total curcuminoids, including “pure” curcumin, bisdemethoxy curcumin and demethoxy curcumin. Bioperine is an extract of Black Pepper fruit that contains 95-98% piperine. Bioperine is added as a natural bioenhancer to promote absorption of the product.

Turmeric - History and Traditional Usage

Native to Southeast Asia, Curcuma longa is a tall tropical shrub with large oblong leaves and pale yellow flowers. The genus “Curcuma” belongs to the Zingiberaceae family, which includes ginger.1 The plant possesses a large root structure with fleshy, bulbous underground parts called “rhizomes.” These rhizomes, known as turmeric root, are harvested at maturity, dried and cured for commercial use. Chemical analysis shows that dried turmeric contains essential and volatile oils, with a curcuminoid content of 2.5 to 5.0 %.2

In addition to its popularity as a spice, turmeric is used as a dye for cloth and as a coloring agent in foods and cosmetics, thanks to its rich yellow color. Turmeric also serves as a preservative, probably owing to the antioxidant and antimicrobial properties of curcumin. Extracts of Curcuma longa have demonstrated in vitro antibacterial and anti-fungal effects.

Turmeric is named in ancient Ayurvedic and Chinese herbal texts as a traditional folk remedy. Historically, turmeric was used externally for wounds, and sprains, and internally for digestive health, joint support, enhancement of liver health, and immune wellness.

Benefits
· Protects cells and tissues by fighting free radicals*
· Supports joint function*

The numerous beneficial effects attributed to turmeric stem in large measure from the antioxidant properties of curcumin. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is a potent “scavenger” of the superoxide radical, a free radical that initiates potentially harmful oxidative processes such as lipid peroxidation.5 Through this activity, curcumin has been shown to protect skin cells from the injurious effect of nitroblue tetrazolium, a toxin that generates superoxide radicals. Curcumin also increases survival of cells exposed in vitro to the enzyme hypoxanthine/xanthine oxidase, which stimulates superoxide and hydrogen peroxide production. Curcumin is not toxic to cells, even at high concentrations. “Pure” curcumin (see first paragraph under “Ingredients” above) was shown to be less protective that a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.6 Because free radicals are involved in aging and exert harmful effects on skin, these results suggest curcumin may help slow skin aging.

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response. Pure curcumin and turmeric extracts protect red blood cells from lipid peroxidation induced by hydrogen peroxide. Curcumin has been shown to protect DNA from oxidative damage, inhibit binding of toxic metabolites to DNA, and reduce DNA mutations in the Ames’ test. Although additional studies suggest an anticarcinogenic effect of curcumin, through protection of DNA, one in vitro study found that curcumin induced DNA damage in human gastric mucosal cells. It is speculated that curcumin may act as a pro-oxidant in the presence of transition metal ions such as copper and iron. (This is true for other antioxidants, including vitamin C.) Curcumin also demonstrates in vitro inhibition of COX-I and COX-II enzymes, which are involved in the inflammatory reaction. Together these results strongly suggest that curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.