Mushroom science is very interesting! Grifron® Maitake D-Fraction® Standard (Tincture) contains purified and standardized "active proteoglucan" from Maitake mushroom (Grifola frondosa) with standard strength. Maiktake D-Fraction is most suitable for regular health maintenance for healthy people. For other purposes "Grifron®-Pro" line with professional strength, which is 4 times more concentrated, is recommended.

The active proteoglucan, often referred to as D-fraction by scientists, is a unique beta-glucan conjugated with protein, which has been identified and isolated as a responsible substance for potent immune-activating property of Maitake mushroom.

Maitake is an edible tasty mushroom prized in Asian countries for centuries. Since the 1980s Maitake mushroom became a subject of scientific studies, and researchers found that it supports healthy immune functions, healthy blood glucose levels and healthy blood pressure in laboratory animals. Our marketing history shows that Grifron® Maitake D-Fraction® Standard is very safe and well tolerated.

Grifron® Maitake D-Fraction® Standard 4 oz. bottle contains 3,000 mg of PD-Fraction, which is standardized to contain more than 900 mg (30%) of the active proteoglucan. Grifron® Maitake D-Fraction® Standard contains no alcohol, sugar, yeast, mold, gluten, dairy products, artificial colors, preservatives, pesticides, herbicides or fertilizers.

What is D-fraction?

Modern science has identified a unique polysaccharide compound, 1,3 branched 1,6 beta-glucan and 1,6 branched 1,3 beta-glucan in Maitake mushroom, which is the active constituent that support immune cell function.* Unlike other 1,3 beta-glucans seen in other medicinal mushrooms such as reishi or shiitake, and also in some yeast cells, Maitake's 1,6 and 1,3 beta-glucans have more complex chemical structures with greater degree of branching, which may increase the chances to reach to each immune cell for activation. Maitake D-fraction is the combination of this 1,6 and 1,3 beta-glucans and some protein. It is most effective when taken orally. It is very important that D-fraction is effective in oral administration, because any pure beta-glucan alone is only effective through injection.