Doctor's Best Calcium Bone Maker Complex 180 Capsules

Doctor's Best Calcium Bone Maker Complex is a science-based nutrition dietary supplement for bone health maintenance. Calcium Bone Maker Complex provides a broad nutrient spectrum for healthy bone replacement, optimized to ensure safe and effective calcium utilization with no magnesium oxide or other poorly absorbed ingredients. Bone Maker Complex promotes skeletal, muscular, overall health and well-being. Bone is living tissue, and this formula supplies key bone nutrients in their most bioactive forms. Ossein microcrystalline hydroxyapatite complex supplies organic calcium with natural bone growth factors. Vitamin C assists bone matrix formation. Vitamin and K are crucial to matrix calcification, along magnesium, potassium, zinc, copper, manganese, and boron. Calcium Bone Maker Complex represents the most advanced clinical understanding of bone health.

Calcium Bone Maker Complex is the new generation bone support supplement, designed from the new understanding of bone as dynamic, complex tissue. Its calcium source is MCH-Cal ossein microcrystalline hydroxyapatite, supplying collagen and other bone matrix proteins and growth factors along with highly bioavailable calcium. This formula is strongly fortified with vitamin D as D3 (cholecalciferol) to help ensure its calcium actually becomes incorporated into bone. It also supplies vitamin K2 as menaquinone-7 (MK-7, the most bioactive vitamin K) to target calcium to bone and away from the soft tissues. The formula also provides generous allowances of vitamin C and the nutritionally essential minerals magnesium, potassium, zinc, copper, manganese, and boron, all necessary for ongoing bone health maintenance.

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This bone health supplement is balanced and synergistic, a product of extensive research into the current medical and scientific understanding of bone. Among this product’s unique benefits:

• Diverse nutrient spectrum for comprehensive bone maintenance.
• Supports bone matrix formation, a requisite for calcium utilization.
• Provides a generous 1800 IU of vitamin D3 for healthy bone calcification.
• Its vitamin K2 (as MK-7) surpasses other K vitamin forms in supporting bone formation.
• Provides optimized allowances of calcium, magnesium, and other essential bone minerals.
• Avoids technical shortcuts that use magnesium oxide or other poorly absorbed ingredients.
• Offers potential benefits that extend beyond bone to promote overall health and wellbeing.

Calcium Is Not Sufficient to Build Bone
Clinical studies have established that high-calcium dietary supplements by themselves do not reliably increase bone density or reduce fracture risk. Many other nutrients are required. The formation of new bone is really a complex process that involves first, building a scaffolding—the bone matrix—then adding in calcium and other minerals to produce hardness and strength. This bone matrix is roughly comparable to the “rebar” that is set in place prior to pouring concrete. The bone’s “concrete” is formed at the end as hard mineral crystals that naturally include not just calcium but magnesium, strontium and other minerals.

The bone matrix is a molecular network primarily of large collagen molecules, interspersed with smaller amounts of other proteins and with large protein-carbohydrate molecules (“glycosaminoglycans”). The ascorbic acid (vitamin C) this formula provides is a necessary factor for the enzymes that make collagen. The formula’s complement of other nutrients is designed to enable the bone cells to build healthy bone matrix and achieve full bone mineralization. But this formula avoids supplying more calcium than the bone matrix can accommodate, especially since recent clinical findings suggest that calcium supplements not balanced by other key bone nutrients may create unnecessary health risks.

Vitamin D Enables Calcium to Build Bone
This formula’s highly active vitamin D3 is converted by the body into a master hormone that regulates calcium activity, not just in bone but all around the body. Bone requires adequate vitamin D to properly form and harden—poor vitamin D status is linked to increased risk for fracture. Poor muscle tone also contributes to risk of falls and consequent fracture, and vitamin D also helps preserve muscle function. The considerable clinical data makes clear that the higher one’s blood vitamin D level, the lower the risk for falls and fractures.

Men as much as women need relatively high blood vitamin D levels to maintain the high bone density that protects against falls and fractures. Yet among adults 65 and older, at least 40 percent are insufficient or deficient in vitamin D. Calcium Bone Maker Complex supplies a generous 1800 International Units of cholecalciferol, the most active form of vitamin D.

Vitamin K Synergizes with Vitamin D to Manage Calcium
Long known as essential for clotting (K stands for Koagulation), vitamin K is also essential for “guiding” calcium to where it belongs (the bones, teeth and other hard tissues), rather than to the soft tissues where calcium’s accumulation can cause serious harm. Just as vitamin K activates the clotting proteins, it is essential to activate several proteins that bind calcium into the forming bone. These include osteocalcin, matrix Gla protein, periostin, and others. Low dietary vitamin K2 intakes are linked to abnormal calcification of the coronaries and other large arteries, the heart valves, the heart muscle, or the kidney tubules. By providing the most active K2 form (MK-7) at 80 micrograms per day, this formula ensures the necessity of vitamin K for healthy bone maintenance.

The crucial bone building contributions of vitamin D, vitamin K, and calcium come together at osteocalcin, the second most abundant protein in bone after collagen. Osteocalcin strongly attracts and binds with calcium to calcify the collagen matrix. Osteocalcin’s production by the bone cells requires vitamin D, and its subsequent activation requires vitamin K.

Magnesium And Other Minerals Also Essential to Bone
Magnesium is essential to healthy bone formation, and especially to support and balance calcium. Magnesium insufficiency is linked with abnormal lowering of calcium in the blood. Some 50-60 percent of the body’s magnesium actually is located in bone.

Several other minerals are crucial for making healthy bone. Zinc is required to make new bone matrix proteins. Copper is essential for enzymes that crosslink collagen into the bone matrix, and also helps balance zinc. Manganese is required by enzymes that make glycoproteins for the bone matrix. Boron supports calcium and magnesium metabolism and probably also bone growth factors. Potassium supports calcium and magnesium utilization and helps conserve healthy bone mineral density.

Calcium Bone Maker Complex is a product of the modern science of bone, superior to supplements that supply merely calcium without the diverse other nutrient essential for bone health. This supplement also reflects the recent findings that high dietary calcium is not necessarily effective for building bone and may even be unsafe: A comprehensive 2010 analysis concluded that taking calcium supplements at intakes higher than 700 mg per day likely increases risk for heart problems. Other meta-analyses suggest that taking calcium supplements without vitamin D may increase the risk for hip fractures. This formula’s provision of vitamin D3 ensures its highly bioavailable calcium will effectively ensure strong bone formation.

Metabolic balance studies are the most precise means for measuring nutrient requirements. Volunteers are confined in a metabolic ward, fed all their meals from a dietetic kitchen, and continuously monitored to determine their total metabolic “economy” of the nutrient being studied. From numerous calcium balance studies, the total dietary calcium needed is reliably estimated at 700-750 mg per day. Calcium intakes from food average at least several hundred milligrams per day, and total intakes over 2,000 mg per day could be risky. The daily 600 mg of calcium from this formula is therefore safe and adequate for the U.S. population.

This formula also avoids taking shortcuts with its nutrient ingredients. For example, magnesium deficiency is widespread in the U.S. and is linked to bone loss and other health problems, yet many supplement products use magnesium oxide which is very poorly absorbed. The recommended dietary allowance of magnesium is 320-420 mg per day. This formula supplies 300 mg per day of magnesium as dimagnesium malate, from which the magnesium is very well absorbed and the malate portion contributes to making energy.

Doctor's Best Calcium Bone Maker Complex does not contain milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives.

About Doctors Best
Doctor's Best firmly believes in the integration of science research and traditional wisdom as the way that nutritional and herbal supplements will reach their exciting potential.

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Careful research and precise formula development keeps us at the leading edge of quality, effectiveness, and innovation.

Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Countless hours have been spent analyzing scientific literature to provide sound alternatives to the proliferation of questionable supplements in the marketplace.

Each of Doctor's Best products is accompanied by an annotated "Fact Sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.

Traditional wisdom ... up-to-date research ... product quality you can trust ... all the information you need to develop smart strategies for achieving optimal health and well-being. Doctor's Best thinks you’ll agree that this combination of products and services is second to none.