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About Doctor's Best

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.

Contact Doctor's Best

197 Avenida La Pata
San Clemente, CA, 92673
http://www.drbvitamins.com
949-498-3628

Doctor's Best - Celadrin 500 mg. - 90 CapsulesSupports Joint Function & Mobility!

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    Doctor's Best - Celadrin 500 mg. - 90 Capsules
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    Item Code: 71681
    UPC Code: 753950001374
    Pricing Info Re-Order
    Retail Price: $24.99
    LuckyVitamin: $11.49
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    Product: Celadrin
    Code#: Lucky ID: 71681 | UPC: 753950001374
    Manufacturer:Doctor's Best
    Size/Form: 90  Capsules
    Packaged Ship Weight: 1  lbs
    Servings: 90
    Dosage Size: 1  Capsule(s)
    Potency Size: 500  mg.
    Auto Re-Order Frequency: More Info



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    Availability: Usually Ships Within 24-48 Hours

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    - (5 ratings) -
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    5 of 5 (100%) of customers said they would recommend
    this product to a friend.


    Description Suggested Use Ingredients Reviews View information about Doctor's Best Show All
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    Doctor's Best - Celadrin 500 mg. - 90 Softgels

    Doctors Best Celadrin is a proprietary blend of esterified fatty acids that have been shown to benefit joint function and flexibility. Being a complex molecule consisting of various fatty acids, it is able to penetrate cell membranes, enhancing membrane permeability and cell-to-cell signaling.

    • Supports Range of Motion in Joints
    • Maintains Joint Comfort

    Celadrin is made from a patented, unique blend of cetylated fatty acids developed through a proprietary process of esterifying oils. Fatty acids such as those in Celadrin are thought to work by influencing cell membrane fluidity and signal transduction pathways and aspects of the immune system (enzymes, cytokines, and cells) involved in joint health. Before human trials, the utility of cetyl myristoleate (derived from an esterified monounsaturated fatty acid) in promoting joint comfort was discovered in 1994 in experiments using rats. Celadrin Complex with Glucosamine also contains a prominent joint-supportive ingredient, glucosamine sulfate.

    Celadrin
    Research has shown that Celadrin can support knee range of motion and joint function. In a groundbreaking double-blind trial that took place at two clinics, 66 participants were randomized to receive either placebo or six capsules of a Celadrin complex (each containing 350 mg Celadrin) daily. Those participants taking the Celadrin complex for 2 months had significantly greater knee flexion (ability to bend the knee) over those taking placebo, in measurements taken at 30 and 68 days into the study.
     
    Glucosamine Sulfate
    Glucosamine sulfate (GS) has been the topic of intense and fruitful research into joint health over the past few decades. Levels of GS seen in the most acclaimed research are offered in Celadrin Complex with Glucosamine. In a recent meta-analysis of six studies involving 1,502 volunteers, it was determined that long-term daily supplementation with glucosamine sulfate (at 1,500 mg for at least 3 years) supported maintenance of knee joint structure over the years, compared to placebo. In a recent report, a British physician and joint health specialist concluded that, “Glucosamine has stood the test of time.”
     
    Glucosamine sulfate (GS) supports joint function by supplying the body with dietary ingredients (glucosamine and sulfur) for building joint cartilage. Glucosamine, a monosaccharide that is essential to the glycosaminoglycans found in cartilage and synovial fluid, stimulates chondrocytes (cartilage cells) to manufacture cartilage building blocks known as proteoglycans. These building blocks contribute to the maintenance of sound joint structure, ultimately enhancing healthy joint function. Additionally, glucosamine inhibits unhelpful catabolic enzymes and can aid in the balance of interleukin-1ß levels in synovial fluid. A recent in vitro investigation examining the molecular biology of chondrocytes found 18 different proteins that were modulated by glucosamine sulfate. In conjunction with other studies, this new evidence suggests that GS fights cytokine-mediated oxidative stress in chondrocytes.
     
    In Europe, implementation of glucosamine for joint health has been studied for four decades, including some of the most comprehensive clinical trials on this ingredient. A 3-year, randomized, placebo-controlled and double-blind study of 202 subjects concluded that glucosamine sulfate is safe and effective in both promoting joint function and maintaining joint structure.

    In addition to its value in influencing joint structure, research also backs the ability of GS to influence joint comfort. A short-term (4-week) randomized, double-blind, parallel-group study of 200 subjects showed that GS taken orally can indeed promote comfortable joint function. Similar results were obtained from a multicenter, randomized, placebo-controlled, double-blind, parallel-group study of 252 subjects, where joint comfort in the knee was found to be higher in the GS group. More recently, a study of 318 subjects found 1,500 mg of GS daily to be more effective than placebo in enhancing joint comfort. Key among findings from these types of studies is the reoccurring theme of a good safety profile for glucosamine sulfate; reported “side effects” of GS were essentially no different than placebo.

    Suggested Use
    One capsule three times daily, with or without food.
    Ingredients

    Doctor's Best - Celadrin 500 mg. - 90 Softgels
    Supplement Facts
    Serving Size: 1 Capsule
    Servings Per Container: 90 Servings
    Amount Per Serving %DV
    Celadrin [a proprietary blend of esterfied fatty acid carbons (EFAC) of myristate, myristolcate, laurate, oleate, palmitate and palmitoleate with tapioca] 500 mg *
    *Daily Value Not Established.
    †Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
     
    Other Ingredients: Gelatin (capsule), cellulose
    About Doctor's Best

    Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.


    197 Avenida La Pata
    San Clemente, CA, 92673
    Phone: 949-498-3628
    Fax: 949-498-3952
    http://www.drbvitamins.com
    Reviews
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    Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

    Average Customer Rating: (4 out of 5)

    Based on 5 rating(s)
    5 of 5 (100%) of customers said they would recommend this product to a friend.
    • By Lucy ( Santa Fe, NM)
      6/13/2011 1:53:32 AM

      I recommend this product!
      most reasonably priced celadrin I've found and it really seems to help my joint pain!
    • By Janet M. ( Tucson, AZ)
      8/31/2011 7:43:06 PM

      I recommend this product!
      Prefer smaller soft gels of NOW brand. Only get this one when NOW is out of stock. It does work equally as good though.
    • By Faye ( Milton, FL)
      8/16/2012 11:45:01 AM

      I recommend this product!
      This helps keep me from hurting. I always take it.
    • By Su ( Miami, FL)
      2/18/2013 7:39:45 AM

      I recommend this product!
      i have been using this celadrin for a few years now, for severe osteoarthritis in my ankle following a compound fracture and bad surgery. the pain that had taken over my life is gone! there's still weakness in my ankle, but i'm back to walking and hiking and dancing. clearly i'm a satisfied customer!
    • By Marky ( Corp Christi, TX)
      6/3/2014 11:14:40 AM

      I recommend this product!
      I read about Celadrin in a health news letter and decided to try it for joint mobility. In 3 days I began to see major improvement and at 70 this is huge! I have told 5 relatives and friends about this supplement and each one has had the same kind of response. We agree that it is the one most important supplement we take. I can see why the lady on the Senior USA Basketball Team wrote about the response she and her team members had to this product. It definitely made a difference in the quality of my life.
    *The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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