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About Doctor's Best

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.

Contact Doctor's Best

197 Avenida La Pata
San Clemente, CA, 92673
http://www.drbvitamins.com
949-498-3628

Doctor's Best - Quercetin Bromelain Vegan Circulatory Support - 180 Vegetarian Capsules

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    Doctor's Best - Quercetin Bromelain Vegan Circulatory Support - 180 Vegetarian Capsules
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    Item Code: 71653
    UPC Code: 753950000292
    Pricing Info Re-Order
    Retail Price: $35.99
    Usual LuckyVitamin Price: $21.67
    Special Promotion: $20.15
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    Product: Quercetin Bromelain Vegan Circulatory Support
    Code#: Lucky ID: 71653 | UPC: 753950000292
    Manufacturer:Doctor's Best
    Size/Form: 180  Vegetarian Capsules
    Packaged Ship Weight: 1  lbs
    Servings: 90
    Dosage Size: 2  Capsule(s)
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    Doctor's Best - Quercetin Bromelain - 180 Capsules

    Doctors Best Quercetin-Bromelain supplies the flavonoid quercetin extracted from seed pods of the Dimorphandra mollis plant. Flavonoids are "semi-essential" nutrients found in many plants and foods. Bromelain is an enzyme complex derived from the pineapple stem. Bromelain supports tissue comfort and may enhance quercetin absorption.

    Quercetin
    Quercetin belongs to the flavonol subgroup of bioflavonoids, a class of compounds that are widely (and colorfully) distributed in plants commonly consumed in the human diet. A brilliant bright yellow compound in its isolated form, quercetin is found in especially high levels (per serving) in onions, kale, tomatoes, and apples. Flavonols, including quercetin, are believed to present specific actions in contributing to the widely known health benefits of fruit and vegetable consumption.
     
    Bromelain
    Bromelain is an enzyme complex derived from the pineapple stem. (Note: G.D.U. stands for “Gelatin-Digesting Units,” a commonly accepted measure of enzyme activity).

    Flavonoids are some of the most abundant and diversely acting ingredients in nature. Despite a staggering accumulation of quercetin literature to date, there is still a long way to go in clinically studying this compound to confirm the preclinical evidence that suggests numerous avenues of health promotion. While the initial focus was on the radical-scavenging abilities of quercetin, it is still unclear to what extent the potential of this characteristic is realized within the human body. Nonetheless, the totality of notable scientific studies together indicates benefits of increased dietary quercetin.
     
    May Support a Healthy Cardiovascular System
    Scientific interest towards quercetin’s potential to support the cardiovascular system was in part generated by results of the epidemiological Zutphen Elderly Study, which suggested that an increased intake of flavonoids, principally represented by intake of quercetin from tea, onions, and apples, was a factor associated with superior cardiovascular health in the participating elderly men. The finding was still significant when adjustments were made for other factors such as age, smoking, blood lipid profile, blood pressure, body-mass index, physical activity, and intake of dietary fiber and other antioxidants like vitamin C and vitamin E.
     
    More recent research in humans, building upon a vast collection of animal and in vitro quercetin studies, has suggested mechanisms behind how quercetin may support a healthy cardiovascular system. Some of the key research suggests that quercetin supports the function of the endothelium, the interface of the vascular system where oxygen and carbon dioxide are exchanged. In one such study (a randomized, placebo-controlled, acute crossover trial), 200 mg of quercetin administered to healthy men apparently was able to modulate circulating concentrations of nitric oxide, an important messenger the body naturally produces to support the healthy flow of blood. Quercetin has also been highlighted as a compound that holds potential in helping to maintain the normal structure and function of endothelial tissue. Since it is generally not feasible to pursue this line of research within the human body, scientists currently rely greatly on in vitro and ex vivo studies to support their theories of why quercetin appears to confer these types of benefits in the cardiovascular arena. The fact that ingesting quercetin from food or supplements can increase blood levels of quercetin is an important factor to consider when evaluating such preclinical research. A recent randomized, double-blinded, placebo-controlled study of 1,023 participants found that daily doses of 500 or 1,000 mg of quercetin produced a significant dose-related increase in blood levels of quercetin in the first month, a gain that was then maintained for the duration of the 12-week study.8 (In this study, vitamin C and niacin were taken concurrently with the quercetin).
     
    Additionally, several recent double-blinded, placebo-controlled studies suggest that over the course of six or more weeks, quercetin supplementation may support healthy blood pressure levels already in the normal range, as well as holding the ability to modulate blood factors. These studies administered quercetin at relatively low doses, such as 150 mg daily. The latest research in humans is so focused on these issues that it is even specific enough to suggest that people with certain genotypes (variations in genetic constitution) are more likely to benefit from quercetin supplementation than others.
     
    May Support a Healthy Respiratory System 
    Human epidemiologic research suggests a relationship between quercetin intake and healthy lung function. In vitro and animal research models are largely in agreement with this finding, also suggesting mechanisms by which quercetin may support healthy respiratory function. Currently, there is some evidence from human studies suggesting that the respiratory system might be supported by quercetin intake, particularly when quercetin is given with vitamin C (a common combination in many food sources of quercetin). For instance, in a randomized, double-blinded, placebo-controlled study of 1,002 participants, the combination of 1,000 mg per day of quercetin with 1,000 mg of vitamin C (plus niacin) for 12 weeks produced some benefit in this area of health among a subgroup of participants over the age of 40 who rated themselves as physically fit. There is also some hope that quercetin may help promote healthy airway function in other ways; at least in preliminary work in guinea pigs, quercetin showed a propensity for helping respiratory function of the guinea pigs when challenged with a substance to which the guinea pigs had been sensitized. Additionally, a recent mouse model has generated some anticipation that quercetin may support healthy airway function by maintaining a healthy balance of immune system cells within the respiratory system. A fairly similar mouse study using Bromelain found that this ingredient also achieved desirable physiological effects.
     
    Areas for further research
    Mixed results have been seen with quercetin supplementation in Sports Nutrition studies. In one study, untrained young adult men took either 1,000 mg of quercetin or placebo for 2 weeks. The enhancement reported was a net change in distance achieved during a 12-minute exercise trial in the men administered quercetin. In another study, this time with elite athletes, 11 male cyclists were administered an antioxidant vitamin regimen, with or without quercetin. Six weeks of the regimen with quercetin (without changes to the cyclists diet, training, or competition schedules) significantly improved high-intensity cycling time trial performance during the competitive road racing session.
     
    Finally, quercetin may be helpful for support of the prostate. Not uncommonly, aging men are concerned with prostate-related pelvic comfort. While the underlying means of support are not entirely clear, there is some early science suggesting that quercetin may promote pelvic comfort for a majority of men in this category.
     
    Bromelain to Enhance Quercetin
    Bromelain has been used in conjunction with quercetin experimentally, as researchers have reason to believe that bromelain may enhance the transport of the bioflavonoids (like quercetin) across the intestinal membrane. At the end of a randomized, double-blinded, placebo-controlled study where participants were administered 500 mg quercetin twice daily, the researchers continued with an open-label style study that supplemented the 500 mg quercetin twice daily with bromelain and papain also. The bromelain and papain apparently contributed greatly to the desired outcome, improving upon the results from quercetin given alone.

    Suggested Use

    Take 2 capsules three times daily, preferably 30 to 60 minutes before meals.

    Ingredients

    Doctor's Best - Quercetin Bromelain - 180 Capsules
    Supplement Facts
    Serving Size: 2 Capsules
    Servings Per Container: 90 Servings
    Amount Per Serving %DV*
    Quercetin 500 mg *
    Bromelain 250 mg *

    (Enzyme activity: 2400 GDU [Gelatin Digesting Units] per gram)

    *Daily Value Not Established.
    †Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
    Other Ingredients: Rice powder, magnesium stearate (vegetable source), silicon dioxide, gelatin (capsule)
    About Doctor's Best

    Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.


    197 Avenida La Pata
    San Clemente, CA, 92673
    Phone: 949-498-3628
    Fax: 949-498-3952
    http://www.drbvitamins.com
    Reviews
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    Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

    Average Customer Rating: (4 out of 5)

    Based on 6 rating(s)
    6 of 6 (100%) of customers said they would recommend this product to a friend.
    • By Cynthia ( Lewes, DE)
      2/11/2010 1:47:25 PM

      I recommend this product!
      I can't say enough about this product and how much it has helped my whole family (including our DOGS) with allergy relief. You can tell when you forgot to take it! I highly recommend this as a natural way to ward off allergies. Experiment with how many capsules you need for it to be effective.
    • By gina ( Arcadia, CA)
      10/4/2011 10:48:08 PM

      I recommend this product!
      I think Dr's Best is a superior vitamin company at great prices. If you suffer from allergies this Quercetin/Bromelain ---which we take daily as we live in a climate where if it is not pollen it is mold--is a godsend . This supplement alone .has decreased the amount of mucus our allergies had us producing by 3/4th ...I highly suggest it...
    • By JANET ( Surprise, AZ)
      10/6/2011 2:20:45 AM

      I recommend this product!
      Helps with allergies and sinus.
    • By JANET ( Surprise, AZ)
      10/6/2011 2:20:45 AM

      I recommend this product!
      Helps with allergies and sinus.
    • By JANET ( Surprise, AZ)
      10/6/2011 2:20:45 AM

      I recommend this product!
      Helps with allergies and sinus.
    • By Shari ( Yuba City, CA)
      12/2/2011 3:35:26 PM

      I recommend this product!
      Packaging is quality, very nice clean information about the product. Only just started on Quercetin Bromelain now for 30 days I do feel there is improvement in my health and I did not expect the added extra energy I have noticed I have now.
    *The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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