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About Doctor's Best

Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.

Contact Doctor's Best

197 Avenida La Pata
San Clemente, CA, 92673
http://www.drbvitamins.com
949-498-3628

Doctor's Best - Best Glucosamine Chondroitin MSM - 240 CapsulesMaintains Healthy Joints & Connective Tissue!

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    Doctor's Best - Best Glucosamine Chondroitin MSM - 240 Capsules
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    Item Code: 71553
    UPC Code: 753950000810
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    Retail Price: $46.99
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    Product: Best Glucosamine Chondroitin MSM
    Code#: Lucky ID: 71553 | UPC: 753950000810
    Manufacturer:Doctor's Best
    Size/Form: 240  Capsules
    Packaged Ship Weight: 1  lbs
    Servings: 120
    Dosage Size: 2  Capsule(s)
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    16 of 16 (100%) of customers said they would recommend
    this product to a friend.

    Description Suggested Use Ingredients Reviews View information about Doctor's Best Show All
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    Doctors Best - Glucosamine Chondroitin MSM 240 Capsules

    Doctors Best Glucosamine Chondroitin MSM contains pure glucosamine sulfate, as confirmed by HPLC testing. Glucosamine sulfate consists of glucosamine, an amino sugar extracted from "chitin," a component of shellfish skeletons. ("Chitin," the resilient polysaccharide that forms the structural framework of animal shells, is a long-chain polymer consisting of many glucosamine molecules linked together.) The purified glucosamine is then sulfated and stabilized with potassium chloride.

    Glucosamine sulfate is derived from the shells of ocean-growing shellfish. It is processed to remove all residues of protein and impurities, yielding pure glucosamine sulfate as the final material.

    Glucosamine/Chondrotin/MSM contains chondroitin sulfate with a purity of 90 percent or greater. Quality assurance testing is performed using two sophisticated laboratory analysis methods: 1) HPLC and 2) C.P.C. Titration, a newly developed method now accepted as the most definitive test for chondroitin sulfate.

    The MSM Story-One of Nature's Primary Sources of Organic Dietary Sulfur!
    The human body requires a continuous supply of usable sulfur, and MSM is one of the primary organic sulfur-containing molecules for use by living organisms. From life's earliest beginnings, primitive marine organisms (blue-green algae and phytoplankton) have absorbed inorganic sulfur from ocean waters and produced organic sulfur molecules, primarily dimethyl sulfonium salts. These salts are released back into the sea, where they are converted to dimethyl sulfide, which readily evaporates, ending up in the upper atmosphere. Dimethyl sulfide is then oxidized by UV light, forming DMSO and MSM. The two compounds are delivered to land masses in rain water, and absorbed by plants. MSM is a stable end product of this process, serving as a primary source of sulfur in the food chain.

    Supports Joint Structure, Function, and Comfort

    The Roles of Glucosamine and Chondroitin Sulfate in Joints
    Articular cartilage is a connective tissue composed of specialized cells (chondrocytes) embedded in a matrix of protein fibers (mostly collagen) and clusters of complex proteoglycan molecules that consist of a protein core with numerous side chains. These side chains, chiefly chondroitin sulfate and keratin sulfate, are long polysaccharide molecules called glycosaminoglycans. Chondroitin sulfate (CS) and the other glycosaminoglycans strongly attract water due to the negative charges of their sulfate groups. These negative charges also repel each other, creating spaces between glycosaminoglycan side chains where water can enter. This combination of solid and liquid gives cartilage a compressible quality that allows it to function as a shock absorber for joints.

    Glucosamine is a fundamental building block for proteoglycans and glycosaminoglycans. Glucosamine sulfate (GS) helps to maintain joint health through its ability to both act as a component of and stimulate formation of cartilage glycosaminoglycans and the hyaluronic acid backbone essential for the formation of cartilage proteoglycans.

    The Abundant Evidence Behind Glucosamine and Chondroitin Sulfate
    Extensive joint health research over the past few decades has investigated the effects of glucosamine sulfate, chondroitin sulfate, or a combination of the two. A 2009 meta-analysis summarized results from 6 well-designed studies involving a total of 1,502 research participants. The authors of this meta-analysis were able to make some conclusions about the apparent effectiveness of long-term oral supplementation with CS or GS. Glucosamine sulfate at 1,500 mg daily over a period of at least 3 years and chondroitin sulfate at 800 mg daily over a period of at least 2 years both helped subjects maintain healthy knee cartilage structure.  In a 2008 review of GS & CS used for joint support, the London physician who wrote it concludes that, “Glucosamine, chondroitin, and the combination of these two agents have stood the test of time.”

    Glucosamine sulfate is one of the most important—and thoroughly researched—dietary supplements for joint health ever developed.  In addition to its potential to influence joint structure (and thus function), research also backs the ability of GS to influence joint comfort. In one such multicenter, randomized, double-blind, parallel-group study of 252 subjects, joint comfort in the knee was found to be higher in the glucosamine sulfate group than the placebo group. Similar studies of equal magnitude found that GS enhanced joint comfort. Key among findings from these types of studies is the reoccurring theme of a good safety profile for glucosamine sulfate; reported “side effects” of GS were essentially no different than placebo.

    Similar to glucosamine, chondroitin sulfate is known to influence the maintenance of healthy cartilage—in this case by acting on matrix metalloproteases (MMPs). Chondroitin sulfate has been shown to inhibit MMP-3 synthesis, which plays an important role in homeostasis of cartilage proteoglycans. Additionally, CS can downplay MMP-13 in chondrocytes, helping to maintain the integrity of articular cartilage matrix.

    Clinical Trials Explore MSM’s Joint Action
    Results from a randomized, double-blind, placebo-controlled pilot trial examining the effect of MSM supplementation on joint comfort in 50 men and women are promising. Subjects taking OptiMSM™ methylsulfonylmethane for 12 weeks experienced greater joint comfort than those taking placebo, suggesting potential for MSM as a joint support nutrient that warrants further investigation in larger clinical trials.  MSM also produced statistically significant changes in urinary malondialdehyde, a marker of oxidative stress.

    MSM has also been used in combination with glucosamine to study their impact on the health of joints. In one such study, a total of 118 subjects were randomized into one of four groups for 12 weeks: glucosamine (500 mg three times daily), MSM (500 mg three times daily), the combination of glucosamine and MSM, or a placebo treatment. Glucosamine alone and MSM alone were shown to enhance joint function, while the combination was found to be even more effective, by both subjective and objective measurements.

    Suggested Use
    Take 2 capsules twice daily, with or without food.

    Warnings

    Glucosamine is obtained from the shells of shellfish.
    Ingredients

    Doctor's Best - Glucosamine Chondroition MSM - 240 Capsules
    Supplement Facts
    Serving Size: 2 Capsules
    Servings Per Container: 120 Servings
    Amount Per Serving %DV**
    Chloride (from glucosamine sulfate 2KCI) 84 mg 2%
    Sodium (from chondroitin sulfate sodium) 28 mg 1%
    Potassium (from glucosamine sulfate 2KCI) 91 mg 3%
    Glucosamine sulfate 2KCI 750 mg  
    Chondroitin sulfate
         (from condroitin sulfate sodium)
    600 mg  
    Methylsulfonylmethane
        OptiMSM
    500 mg  

    **Percent Daily Values are based on a 2,000 calorie diet. Your diet values may be higher or lower depending on your calorie needs.
    Daily Value Not Established.

    Other Ingredients: cellulose, magnesium stearate (vegetable source), gelatin capsule
    About Doctor's Best

    Founded in 1990 by a pioneering physician committed to science-based alternative health care, Doctor’s Best offers only the most important nutritional supplements. Containing the finest quality raw materials from around the world, Doctor’s Best supplements embody the best that traditional knowledge and current scientific research have to offer in the field of therapeutic nutrition. Each of their products is accompanied by an annotated "fact sheet" with detailed background information, structure-function statements, and scientific references that substantiate these statements. All structure-function statements have been filed with FDA in accordance with DSHEA regulations.


    197 Avenida La Pata
    San Clemente, CA, 92673
    Phone: 949-498-3628
    Fax: 949-498-3952
    http://www.drbvitamins.com
    Reviews
    Submit a review for this item
    Disclaimer: The views and opinions expressed by contributors of the product reviews are their own and not necessarily those of LuckyVitamin.com. LuckyVitamin.com does not endorse or imply any medical claims from these reviews. These reviews should not be taken as recommendations but rather customer opinions of the products that they may or may not have used. Reviews are not intended as a substitute for appropriate medical care or advice and are not intended to diagnose, treat, cure, or prevent any disease. Read the full product reviews disclaimer here.

    Average Customer Rating: (5 out of 5)

    Based on 16 rating(s)
    16 of 16 (100%) of customers said they would recommend this product to a friend.
    • By PATTIE ( Cave Junction, OR)
      7/15/2010 3:06:51 PM

      I recommend this product!
      This product works better for pain relief in my arthritic hands than anything else I have used. Actually, all my joints feel better when I use this glucosamine combo regularly.
    • By Debra ( Frankfort, IL)
      7/11/2011 1:41:53 PM

      I recommend this product!
      My husband takes this and swears by its benefits for his aching joints. Reasonable price compared to others with the same ingrediants.
    • By Susan ( Vienna, OH)
      7/27/2011 8:32:10 AM

      I recommend this product!
      I take this formula twice daily to help my joints. At age 66, I appreciate how this formula helps. We even give it to our 10 yr. old Boxer dog.
    • By Susanne ( W Jordan, UT)
      9/2/2011 11:55:22 PM

      I recommend this product!
      My joints needed this and I have more mobility.
    • By teresa ( Burlingame, CA)
      2/9/2012 11:25:14 AM

      I recommend this product!
      good for joint function
    • By barbara ( Waltham, MA)
      4/6/2012 1:49:17 PM

      I recommend this product!
      it works.
    • By John ( Wolcott, CT)
      5/31/2012 9:04:36 AM

      I recommend this product!
      I've used other joint products I can't honestly say these are better or worse. The dosage of the others was 3 pills 3x a day. Dr's Best is 2 capsules twice a day. My joint pain fluctuates from exsistent to nonexsistant. I would say it certainly helps. For the quality and q
    • By VALERIE ( Angelus Oaks, CA)
      9/6/2012 12:05:43 PM

      I recommend this product!
      We use this for our dog. We just sprinkle the powder over her food. It really helps with her joints.
    • By Leasa ( Grovespring, MO)
      12/18/2012 1:56:27 PM

      I recommend this product!
      I take it for joints. Been taking this product on and off for the last 7 years. It does work and i notice that after 3 months of CONSISTANT use -my joints are not swelled and stiff in the mornings (night can be a little different depending on what all i did during the day). The only thing is --this does take TIME. This is not a "fix" for intense joint pain right NOW. I can start feeling a slight difference in about 60-67 days of consistant use. Usually after 3 months -i don't even notice my joints and forget to take it every day and when i run out -i don't order more (save a few bucks). Usually about a year later-i start to remember that i need to get back on this due to my joints start acting up again. If I would just do a maintenance schedule (instead of 4 pills a day -just take 1 or 2 a day) on these all the time--i would probably never have problems with my joints. It is a GOOD product.
    • By Ann ( JAX Bch, FL)
      1/3/2013 11:20:36 AM

      I recommend this product!
      We've been using this for years and can get it from Lucky for 1/2 the price. A win-win for us 1
    • By Guy ( Addis, LA)
      4/17/2013 5:39:09 PM

      I recommend this product!
      I feel much better with this
    • By Linda ( , )
      8/15/2013 10:41:38 AM

      I recommend this product!
      I have severe knee problem, my cartilage was practically none existent, talk about mice in my knees!. I had a lot of pain and my knees would lock up frequently with excruciating pain. I started taking Doctors best Glucosamine Chondroitin with MSM, having tried many other products without results. I am not saying that Doctors Best works for everyone. It does for me. I have been pain free for over twenty years. Thank you for keeping the price affordable
    • By Edward ( Florence, AL)
      8/8/2014 3:53:27 AM

      I recommend this product!
      works good.
    • By jim ( Cypress, TX)
      8/28/2013 11:20:50 AM

      I recommend this product!
      Quality product. Good price.
    • By Sheri ( Walnut Creek, CA)
      5/29/2014 1:36:29 AM

      I recommend this product!
      After almost a month, I've noticed stronger fingernails..
    • By Gerry ( Whittier, CA)
      7/10/2014 4:12:20 PM

      I recommend this product!
      I especially like this product as it is capsules rather than tablets
    *The products and the claims made about specific products on or through this site have not been evaluated by LuckyVitamin.com or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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