Also indexed as:Acetyl Cysteine, NAC
One study reported that 19% of people taking NAC orally experienced nausea, vomiting, headache, dry mouth, dizziness, or abdominal pain.378 These symptoms have not been consistently reported by other researchers, however.
Although a great deal of research has shown that NAC has antioxidant activity, one small study found that daily amounts of 1.2 grams or more could lead to increased oxidative stress.379 Extremely large amounts of cysteine, the amino acid from which NAC is derived, may be toxic to nerve cells in rats.
NAC may increase urinary zinc excretion.380 Therefore, supplemental zinc and copper should be added when supplementing with NAC for extended periods.
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